Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In 20 patients with rheumatoid arthritis (RA), during the first 4 weeks, 8-OHdG decreased in 17 of these patients after drinking the high H₂ water. These findings add human evidence supporting molecular hydrogen's therapeutic potential for rheumatoid arthritis.
Read ArticleIn 3 patients, iL-17, whose concentration was high in Case 1, was reduced following H₂ treatment, and TNFα also decreased in Case 1. These findings add human evidence…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. By drinking 500 ml of the high H₂ water daily for four weeks, oxidative stress was effectively reduced and the…
Read ArticleIn a laboratory model, H₂ decreased the levels of the nitrated proteins, and suppressed chondrocyte death. The authors concluded that moreover, novel pharmacological strategies aimed at selective removal…
Read ArticleIn a laboratory model, treatment with hydrogen reduced LPS/IFNγ-induced NO release, which was associated with a diminished induction of inducible isoform of nitric oxide synthase (iNOS). The authors…
Read ArticleIn rats, drinking hydrogen-rich water suppressed body weight gain, lowered gingival level of 8-hydroxydeoxyguanosine, and reduced alveolar bone resorption in rats on a high-fat diet. These preclinical findings…
Read ArticleIn mice, based on the authors' result, H₂ enriched medium can increase super oxide dismutase (SOD) level following H₂O₂ treatment and decrease 8-hydroxy-2'-deoxyguanosine (8-OHdG) level. These preclinical findings…
Read ArticleIn an animal model, the number of senescence-associated β-galactosidase (SA-β-Gal) positive cells was reduced in BMSCs from rats treated with HRS. These preclinical findings add evidence supporting molecular…
Read ArticleIn rabbits, hydrogen-rich saline significantly decreased the levels of VEGF, TM and LPO and increased the GSH level in steroid-associated necrosis of the femoral head in the rabbit…
Read ArticleIn Methotrexate (MTX) remains a cornerstone of RA treatment, offering significant therapeutic benefits, this is the first case report to highlight severe MTX-induced myelosuppression in an RA patient…
Read ArticleIn rats, treatment with HW abated oxidative stress and suppressed IL-6 and TNF-α mRNA expressions in femur of ovariectomized rats; treatment with HW increased femur endothelial NOS activity…
Read ArticleIn rats, hW showed a protective effect against the progression of OA in an animal model, which may have been mediated by its anti-oxidant and anti-apoptotic activities. These…
Read ArticleIn Sprague-Dawley rats, treatment with HW alleviated HLS-induced reduction of bone mineral density, ultimate load, stiffness, and energy in femur and lumbar vertebra. These preclinical findings add evidence…
Read ArticleThis animal study examined RETRACTED: Hydrogen-rich saline reduces oxidative stress and inflammation by inhibit of JNK and NF-κB activation in a rat model of amyloid-beta-induced Alzheimer’s disease. The…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.
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