A Preliminary Study on the Effect of Hydrogen Gas on Alleviating Early CCl4-Induced Chronic Liver Injury in Rats

This animal study examined A Preliminary Study on the Effect of Hydrogen Gas on Alleviating Early CCl4-Induced Chronic Liver Injury in Rats. The abstract describes Rat model; sample size 32. The abstract reports: We found that CCl can induce significant steatosis in hepatocytes. This is an automated editorial draft based on the abstract and requires source review before publication.

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Renal replacement strategies: dual benefits of hydrogen gas inhalation and hydrogen-enriched dialysate.

This uncontrolled human study examined Renal replacement strategies: dual benefits of hydrogen gas inhalation and hydrogen-enriched dialysate. The abstract describes Human participants; sample size 11; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: Emerging clinical evidence suggests that combining H2 gas inhalation and RRT using H2-enriched dialysate may enhance the management of oxidative stress and inflammation in…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Reduced hemodialysis-induced oxidative stress in end-stage renal disease patients by electrolyzed reduced water.

This uncontrolled human study examined Reduced hemodialysis-induced oxidative stress in end-stage renal disease patients by electrolyzed reduced water. The abstract describes Human participants; reported duration 1 month. The abstract reports: This study demonstrates that hemodialysis with ERW administration may efficiently increase the H2O2- and HOCl-dependent antioxidant defense and reduce H2O2- and HOCl-induced oxidative stress. This is an automated editorial draft based on the abstract and requires source review before publication.

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Pretreatment with hydrogen-rich saline reduces the damage caused by glycerol-induced rhabdomyolysis and acute kidney injury in rats.

This animal study examined Pretreatment with hydrogen-rich saline reduces the damage caused by glycerol-induced rhabdomyolysis and acute kidney injury in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Pretreatment by HRS ameliorated renal dysfunction in glycerol-induced rhabdomyolysis by inhibiting oxidative stress and the inflammatory response. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effects of hydrogen-rich saline on early acute kidney injury in severely burned rats by suppressing oxidative stress induced apoptosis and inflammation.

This uncontrolled human study examined Effects of hydrogen-rich saline on early acute kidney injury in severely burned rats by suppressing oxidative stress induced apoptosis and inflammation. The abstract describes Human participants; hydrogen delivered as hydrogen-rich saline. The abstract reports: Hydrogen can attenuate severe burn-induced early AKI; the mechanisms of protection include the inhibition of oxidative stress induced apoptosis and inflammation, which may be…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Dual Gas Treatment With Hydrogen and Carbon Monoxide Attenuates Oxidative Stress and Protects From Renal Ischemia-Reperfusion Injury.

This animal study examined Dual Gas Treatment With Hydrogen and Carbon Monoxide Attenuates Oxidative Stress and Protects From Renal Ischemia-Reperfusion Injury. The abstract describes Rat model; reported duration 45 minutes. The abstract reports: Dual gas inhalation decreases oxidative stress and markedly improves I-R-induced renal injury. This is an automated editorial draft based on the abstract and requires source review before publication.

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Inhalation of hydrogen gas ameliorates glyoxylate-induced calcium oxalate deposition and renal oxidative stress in mice.

This animal study examined Inhalation of hydrogen gas ameliorates glyoxylate-induced calcium oxalate deposition and renal oxidative stress in mice. The abstract describes Mouse model; reported duration 5 days. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effect of a hydrogen (H2)-enriched solution on the albumin redox of hemodialysis patients.

This uncontrolled human study examined Effect of a hydrogen (H2)-enriched solution on the albumin redox of hemodialysis patients. The abstract describes Human participants. The abstract reports: However, the mean proportion of reversibly oxidized albumin in outlet serum was significantly lower than that in inlet serum following the H2-HD session, whereas…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Inhalation of 4% and 67% hydrogen ameliorates oxidative stress, inflammation, apoptosis, and necroptosis in a rat model of glycerol-induced acute kidney injury

This animal study examined Inhalation of 4% and 67% hydrogen ameliorates oxidative stress, inflammation, apoptosis, and necroptosis in a rat model of glycerol-induced acute kidney injury. The abstract describes Rat model; hydrogen delivered as injected or infused hydrogen. The abstract reports: After 72 hours of glycerol injection (8 mL/kg), we found that glycerol triggered oxidative stress, inflammatory reactions, and apoptotic events. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich water alleviates cyclosporine A-induced nephrotoxicity via the Keap1/Nrf2 signaling pathway.

This animal study examined Hydrogen-rich water alleviates cyclosporine A-induced nephrotoxicity via the Keap1/Nrf2 signaling pathway. The abstract describes Rat model; hydrogen delivered as hydrogen water; reported duration 4 weeks. The abstract reports: We found that CsA increased the levels of reactive oxygen species (ROS) and malonaldehyde (MDA), but it reduced glutathione (GSH) and superoxide dismutase (SOD)…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Oral Hydrogen-Rich Water Alleviates Oxalate-Induced Kidney Injury by Suppressing Oxidative Stress, Inflammation, and Fibrosis.

This animal study examined Oral Hydrogen-Rich Water Alleviates Oxalate-Induced Kidney Injury by Suppressing Oxidative Stress, Inflammation, and Fibrosis. The abstract describes Mouse model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen nanobubble water reduces cochlear inflammation and oxidative stress in noise-induced hearing loss via the gut-inner ear axis.

This animal study examined Hydrogen nanobubble water reduces cochlear inflammation and oxidative stress in noise-induced hearing loss via the gut-inner ear axis. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: Increasing evidence suggests that environmental stress may disrupt gut microbial balance and promote inflammation that leads to distant organs, including cochlea. This is an automated editorial draft based on the abstract and requires source review before publication.

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Exploring the Potential of H2 Therapy in Reducing Surgical Complications: A Review on Anti-inflammatory, Antioxidant, and Anti-fibrotic Mechanisms

This narrative review examined Exploring the Potential of H2 Therapy in Reducing Surgical Complications: A Review on Anti-inflammatory, Antioxidant, and Anti-fibrotic Mechanisms. The abstract describes Published literature review. The abstract reports: Hydrogen is demonstrated to attenuate the early inflammatory response by down-regulating proinflammatory cytokines alongside its anti-oxidative and anti-fibrotic effects. As a potential therapeutic agent…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Alleviation of the chronic stress response attributed to the antioxidant and anti-inflammatory effects of electrolyzed hydrogen water.

This animal study examined Alleviation of the chronic stress response attributed to the antioxidant and anti-inflammatory effects of electrolyzed hydrogen water. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: The results suggest that EHW could suppress stress-response-associated oxidative stress and IL-1β level elevation in vivo, and that drinking of EHW is effective for controlling…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline attenuates eosinophil activation in a guinea pig model of allergic rhinitis via reducing oxidative stress

This animal study examined Hydrogen-rich saline attenuates eosinophil activation in a guinea pig model of allergic rhinitis via reducing oxidative stress. The abstract describes Animal model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: HRS may play a protective role in attenuating allergic inflammation, and suppressing the increase and activation of eosinophils in AR possibly through antioxidation effect…. This is an automated editorial draft based on the abstract and requires source review before publication.

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