Hydrogen-rich saline protects against mitochondrial dysfunction and apoptosis in mice with obstructive jaundice.
This animal study examined Hydrogen-rich saline protects against mitochondrial dysfunction and apoptosis in mice with obstructive jaundice. The abstract describes Mouse model; sample size 6; hydrogen delivered as hydrogen-rich saline. The abstract reports: Previous studies have demonstrated that hydrogen-rich saline (HS) protects against bile duct ligation (BDL)-induced liver injury by suppressing oxidative stress and inflammation. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreConcomitant inhibition of oxidative stress and angiogenesis by chronic hydrogen‐rich saline and N‐acetylcysteine treatments improves systemic, splanchnic and hepatic hemodynamics of cirrhotic rats
This animal study examined Concomitant inhibition of oxidative stress and angiogenesis by chronic hydrogen‐rich saline and N‐acetylcysteine treatments improves systemic, splanchnic and hepatic hemodynamics of cirrhotic rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline; reported duration 1 month. The abstract reports: Both hydrogen-rich saline and N-acetylcysteine alleviate portal hypertension, the severity of portosystemic collaterals, mesenteric angiogenesis, hepatic endothelial dysfunction and intrahepatic resistance in cirrhotic rats.…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhalation of hydrogen gas suppresses hepatic injury caused by ischemia/reperfusion through reducing oxidative stress.
This animal study examined Inhalation of hydrogen gas suppresses hepatic injury caused by ischemia/reperfusion through reducing oxidative stress. The abstract describes Mouse model; reported duration 90 min. The abstract reports: We have recently showed that molecular hydrogen has great potential for selectively reducing cytotoxic reactive oxygen species, such as hydroxyl radicals, and that inhalation…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHigh-content hydrogen water-induced downregulation of miR-136 alleviates non-alcoholic fatty liver disease by regulating Nrf2 via targeting MEG3.
This animal study examined High-content hydrogen water-induced downregulation of miR-136 alleviates non-alcoholic fatty liver disease by regulating Nrf2 via targeting MEG3. The abstract describes Mouse model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effects of hydrogen enriched saline on liver ischemia reperfusion injury by reducing oxidative stress and HMGB1 release.
This animal study examined Protective effects of hydrogen enriched saline on liver ischemia reperfusion injury by reducing oxidative stress and HMGB1 release. The abstract describes Rat model; hydrogen delivered as injected or infused hydrogen. The abstract reports: These results suggest that, in our model, hydrogen enriched saline treatment is protective against liver ischemia-reperfusion injury. This effect may be mediated by both…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreIntake of Molecular Hydrogen in Drinking Water Increases Membrane Transporters, -Glycoprotein, and Multidrug Resistance-Associated Protein 2 without Affecting Xenobiotic-Metabolizing Enzymes in Rat Liver.
This animal study examined Intake of Molecular Hydrogen in Drinking Water Increases Membrane Transporters, -Glycoprotein, and Multidrug Resistance-Associated Protein 2 without Affecting Xenobiotic-Metabolizing Enzymes in Rat Liver. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: The results showed that intake of HRW had no significant effect on the activities of various cytochrome P450 (CYP) enzymes (CYP1A1, 1A2, 2B, 2C,…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich water prevents progression of nonalcoholic steatohepatitis and accompanying hepatocarcinogenesis in mice.
This animal study examined Hydrogen-rich water prevents progression of nonalcoholic steatohepatitis and accompanying hepatocarcinogenesis in mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water; reported duration 8 weeks. The abstract reports: Consumption of hydrogen-rich water may be an effective treatment for NASH by reducing hepatic oxidative stress, apoptosis, inflammation, and hepatocarcinogenesis. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen attenuates hypoxia/reoxygenation injury of intrahepatic cholangiocytes by activating Nrf2 expression.
This animal study examined Molecular hydrogen attenuates hypoxia/reoxygenation injury of intrahepatic cholangiocytes by activating Nrf2 expression. The abstract describes Rat model. The abstract reports: We found that H2 ameliorated H/R-induced cholangiocytes apoptosis. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffect of hydrogen-rich water on oxidative stress, liver function, and viral load in patients with chronic hepatitis B.
This uncontrolled human study examined Effect of hydrogen-rich water on oxidative stress, liver function, and viral load in patients with chronic hepatitis B. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: HRW significantly attenuates oxidative stress in CHB patients, but further study with long-term treatment is required to confirm the effect of HRW on liver…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreLong-term consumption of hydrogen-rich water provides hepatoprotection by improving mitochondrial biology and quality control in chronically stressed mice.
This animal study examined Long-term consumption of hydrogen-rich water provides hepatoprotection by improving mitochondrial biology and quality control in chronically stressed mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: This study reveals that long-term hydrogen-rich water (HRW) consumption provides significant hepatoprotection in mice under chronic stress. HRW normalizes liver enzyme levels, enhances antioxidant…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreLong-Term Consumption of Hydrogen-Rich Water Mitigates Oxidative Stress, Hepatic Inflammation, and Apoptosis in Rats with LPS-Induced Chronic Liver Injury.
This animal study examined Long-Term Consumption of Hydrogen-Rich Water Mitigates Oxidative Stress, Hepatic Inflammation, and Apoptosis in Rats with LPS-Induced Chronic Liver Injury. The abstract describes Rat model; hydrogen delivered as hydrogen water; reported duration 8 months. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreA Novel Antioxidant, Hydrogen-Rich Coral Calcium Alters Gut Microbiome and Bile Acid Synthesis to Improve Methionine-and-Choline-Deficient Diet-Induced Non-Alcoholic Fatty Liver Disease.
This animal study examined A Novel Antioxidant, Hydrogen-Rich Coral Calcium Alters Gut Microbiome and Bile Acid Synthesis to Improve Methionine-and-Choline-Deficient Diet-Induced Non-Alcoholic Fatty Liver Disease. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: In the present study, we found that HRCC treatment improved methionine-and-choline-deficient diet (MCD)-induced hepatic steatosis, increased aspartate aminotransferase and alanine aminotransferase levels, and elevated…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-Rich Water (HRW) Reduces Fatty Acid-Induced Lipid Accumulation and Oxidative Stress Damage through Activating AMP-Activated Protein Kinase in HepG2 Cells.
This in vitro or cellular study examined Hydrogen-Rich Water (HRW) Reduces Fatty Acid-Induced Lipid Accumulation and Oxidative Stress Damage through Activating AMP-Activated Protein Kinase in HepG2 Cells. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen water. The abstract reports: Some clinical evidence suggests that H may alleviate fatty liver disease, but the precise molecular mechanisms, particularly the regulation of lipid droplet (LD) metabolism,…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas ameliorates acute alcoholic liver injury via anti-inflammatory and antioxidant effects and regulation of intestinal microbiota.
This animal study examined Hydrogen gas ameliorates acute alcoholic liver injury via anti-inflammatory and antioxidant effects and regulation of intestinal microbiota. The abstract describes Mouse model. The abstract reports: Hydrogen gas (H) has been demonstrated to be an efficient antioxidant in various diseases in animals as well as humans. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreLong-term and daily use of molecular hydrogen induces reprogramming of liver metabolism in rats by modulating NADP/NADPH redox pathways.
This animal study examined Long-term and daily use of molecular hydrogen induces reprogramming of liver metabolism in rats by modulating NADP/NADPH redox pathways. The abstract describes Rat model. The abstract reports: Rats exposed 2 h daily to H either by drinking HRW (H dissolved in HO) or by breathing 4% H gas showed reduced lipogenesis and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreBlog Categories
Recent Posts
October 21, 2020
November 16, 2020
October 02, 2017