Hydrogen improves neurological function through attenuation of blood-brain barrier disruption in spontaneously hypertensive stroke-prone rats.
This animal study examined Hydrogen improves neurological function through attenuation of blood-brain barrier disruption in spontaneously hypertensive stroke-prone rats. The abstract describes Rat model; sample size 28; hydrogen delivered as hydrogen water. The abstract reports: The present study suggests that ingestion of HRW can improve neurological function outcome in the SHRSP model. This beneficial effect may be due to…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreNeuroprotective Effect of Hydrogen-Rich Saline in Global Cerebral Ischemia/Reperfusion Rats: Up-Regulated Tregs and Down-Regulated miR-21, miR-210 and NF-κB Expression.
This animal study examined Neuroprotective Effect of Hydrogen-Rich Saline in Global Cerebral Ischemia/Reperfusion Rats: Up-Regulated Tregs and Down-Regulated miR-21, miR-210 and NF-κB Expression. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Recently, it has been suggested that molecular hydrogen (H) can selectively reduce the levels of hydroxyl radicals (.OH), and ameliorate oxidative and inflammatory injuries…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline protects against oxidative damage and cognitive deficits after mild traumatic brain injury.
This uncontrolled human study examined Hydrogen-rich saline protects against oxidative damage and cognitive deficits after mild traumatic brain injury. The abstract describes Human participants; hydrogen delivered as hydrogen-rich saline. The abstract reports: Oxidative stress is the principal factor in traumatic brain injury (TBI) that initiates events that result in protracted neuronal dysfunction and remodeling. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas inhalation improves delayed brain injury by alleviating early brain injury after experimental subarachnoid hemorrhage.
This in vitro or cellular study examined Hydrogen gas inhalation improves delayed brain injury by alleviating early brain injury after experimental subarachnoid hemorrhage. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen inhalation. The abstract reports: CV showed no significant improvement between the control and H groups. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhalation of hydrogen gas attenuates cognitive impairment in transient cerebral ischemia via inhibition of oxidative stress.
This animal study examined Inhalation of hydrogen gas attenuates cognitive impairment in transient cerebral ischemia via inhibition of oxidative stress. The abstract describes Rat model; sample size 30; reported duration 3 hours. The abstract reports: Inhalation of hydrogen gas could attenuate cognitive impairment in the ischemic rats. This protection is associated with decreased neuronal death in CA1 region and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effects of hydrogen-rich saline in a rat model of traumatic brain injury via reducing oxidative stress.
This uncontrolled human study examined Protective effects of hydrogen-rich saline in a rat model of traumatic brain injury via reducing oxidative stress. The abstract describes Human participants; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Hydrogen-rich saline can exert a protective effect against TBI via reducing oxidative stress. Molecular hydrogen may be a more effective therapeutic strategy for TBI…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffect of hydrogen gas on the survival rate of mice following global cerebral ischemia.
This animal study examined Effect of hydrogen gas on the survival rate of mice following global cerebral ischemia. The abstract describes Mouse model; sample size 12. The abstract reports: Global cerebral ischemia and reperfusion (I/R) often result in high mortality. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas ameliorates oxidative stress in early brain injury after subarachnoid hemorrhage in rats.
This animal study examined Hydrogen gas ameliorates oxidative stress in early brain injury after subarachnoid hemorrhage in rats. The abstract describes Rat model; reported duration 2 hrs. The abstract reports: Hydrogen gas could exert its neuroprotective effect against early brain injury after subarachnoid hemorrhage by its antioxidative activity. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-Rich Saline—A Novel Neuroprotective Agent in a Mouse Model of Experimental Cerebral Ischemia via the ROS-NLRP3 Inflammasome Signaling Pathway In Vivo and In Vitro
This animal study examined Hydrogen-Rich Saline—A Novel Neuroprotective Agent in a Mouse Model of Experimental Cerebral Ischemia via the ROS-NLRP3 Inflammasome Signaling Pathway In Vivo and In Vitro. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: HS, as a novel therapeutic option, could exert protect the brain by inhibiting the activation of the ROS-NLRP3 signaling pathway after cerebral ischemia. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen inhalation promotes recovery of a patient in persistent vegetative state from intracerebral hemorrhage: A case report and literature review.
This case report or case series examined Hydrogen inhalation promotes recovery of a patient in persistent vegetative state from intracerebral hemorrhage: A case report and literature review. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: Phase 1 clinical trials are needed to explore the safety and efficacy of H gas inhalation in patients with PVS. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline alleviates early brain injury through inhibition of necroptosis and neuroinflammation via the ROS/HO-1 signaling pathway after traumatic brain injury.
This animal study examined Hydrogen-rich saline alleviates early brain injury through inhibition of necroptosis and neuroinflammation via the ROS/HO-1 signaling pathway after traumatic brain injury. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Hydrogen, which is a slight and specific cytotoxic oxygen radical scavenger, has been demonstrated to ameliorate early brain injury (EBI) through reactive oxygen species…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreRole of hydrogen in traumatic brain injury: a narrative review.
This narrative review examined Role of hydrogen in traumatic brain injury: a narrative review. The abstract describes Published literature review. The abstract reports: In this review, we will focus on the results of hydrogen in experimental TBI, elaborate the potential mechanisms, and put forward for future researches…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline alleviates early brain injury through regulating of ER stress and autophagy after experimental subarachnoid hemorrhage
This animal study examined Hydrogen-rich saline alleviates early brain injury through regulating of ER stress and autophagy after experimental subarachnoid hemorrhage. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The results of this study demonstrate that hydrogen-rich saline improves neurological outcomes in mice and reduces neuronal death by protecting against neural autophagy and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Inhalation Attenuates Oxidative Stress Related Endothelial Cells Injury After Subarachnoid Hemorrhage in Rats.
This animal study examined Hydrogen Inhalation Attenuates Oxidative Stress Related Endothelial Cells Injury After Subarachnoid Hemorrhage in Rats. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation; reported duration 3 days. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreLongitudinal multiparametric MRI study of hydrogen-enriched water with minocycline combination therapy in experimental ischemic stroke in rats.
This animal study examined Longitudinal multiparametric MRI study of hydrogen-enriched water with minocycline combination therapy in experimental ischemic stroke in rats. The abstract describes Rat model. This is an automated editorial draft based on the abstract and requires source review before publication.
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