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Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In rats, effect of hydrogen on S100- β and NSE levels The levels of S100-β and NSE have similar trends, these increased in the I/R group compared with those of the sham group ( P <0.05), but hydrogen treatment decreased their levels…
Read ArticleIn rats, hydrogen-rich water administration significantly increased 7-d survival rates, reduced neurologic deficits, and lowered intracellular oxidative stress levels. These preclinical findings add evidence supporting molecular hydrogen's therapeutic…
Read ArticleIn Sprague-Dawley rats, bcl-2 was significantly increased while Bax and cleaved caspase-3 was decreased by HS treatment. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within…
Read ArticleIn contrast, the upregulated level of MDA, caspase-12/3 and brain edema was attenuated and the brain injury was substantially alleviated in the hydrogen treated rabbits, but the improvement…
Read ArticleIn mice, hydrogen inhalation significantly reduced infarct volume, attenuated brain edema and improved neurobehavioral deficit in MCAO mice. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential…
Read ArticleIn rats, these results demonstrated that H₂ significantly reduced the number of apoptotic cells, and the protein expression of p38 MAPK and caspase‑3, compared with the IR group.…
Read ArticleIn Sprague-Dawley rats, hydrogen administration reduced the expression of 8-OHdG in the brain, but did not attenuate brain water content or improve functional outcome, regardless of administration route.…
Read ArticleThese results show that molecular hydrogen given in drinking water reverses many of the sequelae of CCI and suggests that it could be an easily administered, highly effective…
Read ArticleIn a laboratory model, hydrogen treatment diminished phosphorylation of Lyn kinase and release of tryptase, decreased accumulation and degranulation of mast cells, attenuated blood-brain barrier disruption, and improved…
Read ArticleIn male Sprague-Dawley rats, hydrogen treatment significantly reduced the level of oxidative stress, neuroinflammation, neuronal damage, and apoptosis-related genes. These preclinical findings add evidence supporting molecular hydrogen's therapeutic…
Read ArticleThe results demonstrated that TBI-challenged rats exhibited significant brain injuries that were characterized by decreased survival rate and increased BBB permeability, brain edema, and neurological dysfunction, while HRW…
Read ArticleIn mice, the hydrogen inhalation reduced these effects acutely (24 h); however it exhibited only a tendency to improvement in the delayed study (72 h). These preclinical findings…
Read ArticleIn rats, HRW treatment improved neurological function and tended to improve overall survival but without significant difference. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within…
Read ArticleIn rats, rats undergone global cerebral I/R and treated with HRS have milder injury than I/R animals without HRS treatment. miR-210 expression in the hippocampus of the I/R…
Read ArticleIn an animal model, treatment with hydrogen-rich saline, which elevated the levels of molecules associated with brain-derived neurotropic factor (BDNF)-mediated synaptic plasticity, improved cognitive performance in the Morris…
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