Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In rats, compared to MNU-treated rats, retinal malondialdehyde (MDA) content in MNU + hydrogen-rich saline rats significantly decreased while superoxide dismutase (SOD) activity significantly increased. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured…
Read ArticleIn rats, hRS preserved the retinal function and mitigated the reduction of photoreceptor degeneration in MNU-treated retinas. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within…
Read ArticleIn Sprague-Dawley rats, however, HRS exerted an inhibition trend on elevation of protein in AqH of EIU induced by 1 mg/kg of LPS, and significantly reduced the increasing…
Read ArticleIn conclusion, hydrogen molecule may be neuroprotective against ALS, possibly through abating oxidative and nitrosative stress and preserving mitochondrial function. These preclinical findings add evidence supporting molecular hydrogen's…
Read ArticleIn vitro studies also confirmed the anti-proliferative capability of the hydrogen solution and ROS generation in VSMCs induced by PDGF-BB. The authors concluded that hRSS may have a…
Read ArticleIn rats, the sphere-forming ability of glioma cells was also suppressed by hydrogen treatment. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and…
Read ArticleIn rats, it was found that systemic HRW treatment slightly suppressed autophagy and then activated the Keap1-Nrf2 signaling pathway by maintaining the Keap1-Nrf2-P62 interaction and improved the osteoporotic…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Studies have shown that H₂ inhalation for about 2 weeks can restore the body’s redox balance and enhance immune cells’…
Read ArticleIn rats, hydrogen-rich saline treatment significantly attenuated lung injury as indicated by significantly improved histological changes in lung, significantly reduced index of quantitative assessment (IQA), MDA content and…
Read ArticleIn rats, histologically, significant increases were found in glomerular adhesion, cardiac fibrosis, number of ED-1 (CD68)-positive cells and nitrotyrosine staining in the contralateral kidney and the heart. These…
Read ArticleIn rats, the edema area in TBI+HW group was slightly smaller than that of TBI group, and the surrounding edema was slightly reduced. These preclinical findings add evidence…
Read ArticleIn rats, the mRNA and protein expressions of AQP1 in cerebral cortex were significantly decreased after hydrogen-rich water treatment [24-hour AQP1 mRNA (2-△△Ct):5.40±0.21 vs.7.50±0.26, 24-hour AQP1 protein (gray…
Read ArticleThe researchers found that the proportion of terminal PD-1+ CD8+ T cells was reduced in 35 out of 55 patients(63.6%)and was increased in 39 out of 55 patients(70.9%)after…
Read ArticleIn rats, compared with the model group, the inflammatory response of pregnancy gingivitis in HW group was significantly suppressed along with decreased NFκB and TNF-α. These preclinical findings…
Read ArticleHydrogen-rich saline reduced renal inflammatory-cytokine expression and improved several kidney-injury measures in severely burned rats. These results are preclinical and suggest molecular hydrogen's therapeutic potential in the condition…
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