Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In mice, when compared to C group, both the Model group and the HRW group showed a significant reduction in the protein expression levels of iron death-related markers GPX4 and SLC7A11 (P < 0.05). These preclinical findings add evidence supporting molecular hydrogen's…
Read ArticleIn Sprague-Dawley rats, long-term HRW consumption significantly reduced LPS-induced inflammatory cell infiltration in liver tissue, suppressed the abnormal elevation of pro-inflammatory factors, and maintained relatively stable expression levels…
Read ArticleIn mice, among these, Acaca, Fasn, and CD36 were decreased ( Figures 2G-I ), while Mttp and Apob were increased by high dose H₂ therapy ( Figures 2N,O…
Read ArticleIn the present study, the researchers found that HRCC treatment improved methionine-and-choline-deficient diet (MCD)-induced hepatic steatosis, increased aspartate aminotransferase and alanine aminotransferase levels, and elevated hepatic inflammatory factor…
Read ArticleIn This study utilized an in vitro model of hepatocyte lipid accumulation induced by free fatty acids (FFAs) to replicate MASLD in HepG2 cells, as shown in Figure…
Read ArticleIn mice, H₂ inhalation improved gut microbiota, including increasing the abundance of Lachnospiraceae and Clostridia, and decreasing the abundance of Prevotellaceae and Muribaculaceae, and also improved intestinal barrier…
Read ArticleIn mice, intraperitoneal injection of H₂ improved acute ethanol-induced liver injury in mice in a dose dependent manner, as indicated by decreasing serum ALT and AST levels, hepatic…
Read ArticleThis publication examined hydrogen gas using the study design reported by the authoritative source. No study results are reported because this publication is a protocol.
Read ArticleIn rats, rats exposed 2 h daily to H₂ either by drinking HRW (H₂ dissolved in H₂O) or by breathing 4% H₂ gas showed reduced lipogenesis and enhanced…
Read ArticleIn mice, the study verified a catalytic strategy of combining PdH nanoparticles and hydrogen inhalation, which exhibited enhanced anti-inflammatory effect for CLD treatment. These preclinical findings add evidence…
Read ArticleIn 30 participants with NAFLD, HRW was well-tolerated, with no significant changes in liver enzymes and a trend of improved lipid profile and reduced lactate dehydrogenase levels. These…
Read ArticleIn rats, when the hydrogen gas was inhaled, hepatocyte steatosis was reduced, and the UCP2 expression level in liver tissue was increased. These preclinical findings add evidence supporting…
Read ArticleIn an animal model, HRW improved hepatic steatosis in the CSAA + HRW group. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and…
Read ArticleIn 6 patients, there were substantial changes in surrogate markers, such as increased CA125 and mesothelin, in the effluent in selected cases, suggesting enhanced mesothelial regeneration by H₂.…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. H₂ gas inhalation has been associated with improved recovery from ischemia-reperfusion injury, which is commonly encountered with kidney transplants and…
Read Article