Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In rats, r(2)* values in the cortex were significantly decreased on Days 2, 4, and 7 compared with those on Day 0 in the GM group but not significantly changed in the control and GM+HW groups. These preclinical findings add evidence supporting…
Read ArticleHemodialysis reduced the plasma ROS scavenging activity, as shown by the augmented reference H₂O₂ and HOCl counts (Rh2o2 and Rhocl, respectively) and decreased antioxidative activity (expressed as total…
Read ArticleIn male Sprague-Dawley rats, 6d ), although there were statistically significant differences in M30 CytoDeath-positive cells (0.7 ± 0.1 and 0.9 ± 0.2 positive cells/field in the Fe-HD…
Read ArticleFollowing the introduction of hydrogen therapy, her renal function improved, evidenced by a reduction in serum creatinine levels.
Read ArticleThis narrative review examined the available molecular-hydrogen literature. H₂ was produced continuously, which allowed the concentration of H₂ in the water to reach 1.61 mg/L at 20°C. The…
Read ArticleIn blood gases, pH, PaO 2, and BE decreased and lactate increased, but recovered to baseline after 3 h, with no difference between the HI and HI-H₂ groups…
Read ArticleIn rats, hRS reversed these changes, with the exception of HO-1 expression, which was increased further, and improved renal morphology. These preclinical findings add evidence supporting molecular hydrogen's…
Read ArticleIn an animal model, marginal kidney processed by hydrogen gas-containing preservation solution has been engrafted for long-term (longer than 100 days). These preclinical findings add evidence supporting molecular…
Read ArticleIn an animal model, after storage of the kidney in hydrogen-free preservation solution for 1 hour before transplantation, no urine production was observed and blood flow was not…
Read ArticleIn an animal model, nineteen serum metabolites and 7 urine metabolites showed significant restoration to normal levels after hydrogen gas (H₂) treatment. These preclinical findings add evidence supporting…
Read ArticleIn mice, however, the proportion of M1-type macrophages was significantly lower and the proportion of M2-type macrophages was significantly higher in the hydrogen-rich-medium-treated LPS/IFN-γ group than in the…
Read ArticleIn male Sprague-Dawley rats, kEY FINDINGS: the researchers demonstrated that rats who inhale hydrogen gas showed improved renal function, alleviated pathological damage, oxidative stress and apoptosis in CIH…
Read ArticleIn rats, after I/R injury, BUN, Cr, Bcl-2, caspase-3, caspase-9, caspase-8, IL-6, and TNF-α were all significantly increased, while Bax expression was decreased. These preclinical findings add evidence…
Read ArticleIn contrast, treatment with HW improved allograft function, slowed the progression of CAN, reduced oxidant injury and inflammatory mediator production, and improved overall survival. These preclinical findings add…
Read ArticleIn rats, as shown in Figures 7(d) and 8(c), the expression of I κ B and IL-10 in renal tissues at 12 hours was significantly decreased after SAP…
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