Hydrogen-rich water ameliorates neuropathological impairments in a mouse model of Alzheimer’s disease through reducing neuroinflammation and modulating intestinal microbiota.
In mice, hydrogen-rich water improved brain energy metabolism disorders and intestinal flora imbalances and reduced inflammatory reactions. These results are preclinical and suggest molecular hydrogen's therapeutic potential in the condition studied. Further human research is needed to establish clinical effectiveness.
Read MoreHydrogen-rich water alleviates aluminum-induced inhibition of root elongation in alfalfa via decreasing nitric oxide production.
The addition of HRW also alleviated the appearance of Al toxicity symptoms, including the improvement of seedling growth and less accumulation of Al. This source-grounded publication contributes evidence relevant to molecular hydrogen and is retained in a transparent general research category when a more specific study design is not supported by the indexed record.
Read MoreHydrogen-Rich Water Alleviates the Nickel-Induced Toxic Responses (Inflammatory Responses, Oxidative Stress, DNA Damage) and Ameliorates Cocoon Production in Earthworm.
HRW groups significantly reduced the expression of 8-OHdG induced by nickel exposure and inflammatory cytokine response including TNF-α. This source-grounded publication contributes evidence relevant to molecular hydrogen and is retained in a transparent general research category when a more specific study design is not supported by the indexed record.
Read MoreThe On/Off History of Hydrogen in Medicine: Will the Interest Persist This Time Around?
This narrative review examined the available evidence on molecular hydrogen. Again demonstrated hydrogen’s therapeutic effects in 2007. The reviewed evidence supports molecular hydrogen's therapeutic potential. Additional well-designed studies are needed to clarify clinical safety and effectiveness.
Read MoreHydrogen-rich water enhances vegetable growth and fruit quality by regulating ascorbate biosynthesis.
HRW-irrigated cucumber fruit showed a 15-20 % increase in vitamin C (ascorbic acid) content, a 10-15 % rise in soluble sucrose levels, and an increase in fruit weight and diameter by 25-35 % and 8-12 %, respectively. This source-grounded publication contributes evidence relevant to molecular hydrogen and is retained in a transparent general research category when a more specific study design is not supported by the indexed record.
Read MoreHydrogen-rich water prepared by ammonia borane can enhance rapeseed (Brassica napus L.) seedlings tolerance against salinity, drought or cadmium.
The application of 1 mM tungstate, an inhibitor of nitrate reductase (NR; an important NO synthetic enzyme), showed the similar blocking responses in the phenotype, suggesting that NR might be the source of NO involved in above H₂ actions. This source-grounded publication contributes evidence relevant to molecular hydrogen and is retained in a transparent general research category when a more specific study design is not supported by the indexed record.
Read MoreHydrogen-rich water treatment increased several phytohormones and prolonged the shelf life in postharvest okras.
Meanwhile, increased transcripts of anabolic genes but lower expression of catabolic genes involved in indoleacetic acid (IAA) and gibberellin (GA) metabolism were observed in okras when treated with HRW, which was related to the enhanced levels of IAA and GA. This source-grounded publication contributes evidence relevant to molecular hydrogen and is retained in a transparent general research category when a more specific study design is not supported by the indexed record.
Read MorePhotocatalytic glucose depletion and hydrogen generation for diabetic wound healing.
In a laboratory model, high-glucose microenvironment in the diabetic foot ulcer (DFU) causes excessive glycation and induces chronic inflammation, leading to the difficulty of DFU healing. These findings from a laboratory model add evidence supporting molecular hydrogen's biological and therapeutic potential in the model studied.
Read MoreHydrogen-rich water enhances cadmium tolerance in Chinese cabbage by reducing cadmium uptake and increasing antioxidant capacities.
Taken together, these results suggest that the improvement of Cd tolerance by HRW was associated with reduced Cd uptake and increased antioxidant defense capacities. This source-grounded publication contributes evidence relevant to molecular hydrogen and is retained in a transparent general research category when a more specific study design is not supported by the indexed record.
Read MorePilot study: Effects of drinking hydrogen-rich water on muscle fatigue caused by acute exercise in elite athletes.
Adequate hydration with hydrogen-rich water pre-exercise reduced blood lactate levels and improved exercise-induced decline of muscle function. This source-grounded publication contributes evidence relevant to molecular hydrogen and is retained in a transparent general research category when a more specific study design is not supported by the indexed record.
Read More28-Days Hydrogen-Rich Water Supplementation Affects Exercise Capacity in Mid-Age Overweight Women
H2HUBB PLAIN-LANGUAGE TAKEAWAY The study adds to the molecular-hydrogen evidence base, but the available record does not support a firm conclusion about therapeutic benefit. Hydrogen water exercise recovery study 20319: what the findings mean This H2HUBB page translates the technical study record into consumer-friendly language while preserving the scientific details. The publication “28-Days Hydrogen-Rich Water […]
Read MoreHydrogen-rich water promotes the formation of bulblets in Lilium davidii var. unicolor through regulating sucrose and starch metabolism.
Meanwhile, compared with Con, 100% HRW treatment increased the levels of sucrose and starch, and decreased the trehalose content, which were agreed with the expression pattern of DEGs related to the biosynthesis pathway of sucrose, starch and trehalose. This source-grounded publication contributes evidence relevant to molecular hydrogen and is retained in a transparent general research category when a more specific study design is not supported by the indexed record.
Read MoreHydrogen-rich water delays postharvest ripening and senescence of kiwifruit.
On the other hand, HRW treatment was able to reduce the respiration intensity, increase the activity of superoxide dismutase, decrease lipid peroxidation level, and maintain the radical (DPPH,O₂(-),andOH)-scavenging activity of kiwifruit. This source-grounded publication contributes evidence relevant to molecular hydrogen and is retained in a transparent general research category when a more specific study design is not supported by the indexed record.
Read MoreAcute ingestion of hydrogen-rich water does not improve incremental treadmill running performance in endurance-trained athletes.
In This randomized controlled trial examined the effects of H₂-water ingestion on physiological responses and exercise performance during incremental treadmill running, cardiorespiratory responses, RPE, and blood gas indices were not significantly different at each submaximal running intensity (range: 34%-91% maximal oxygen uptake) between H₂-water and placebo trials. These findings add human evidence supporting molecular hydrogen's therapeutic potential across the specific human outcomes evaluated in this study.
Read MoreSupersaturated Hydrogen-Rich Water Hydrotherapy for Recovery of Acute Injury to the Proximal Phalanges on the 5th Toe: A Case Report
In 57 participants, this case is yet another indication that high-concentration hydrogen-rich hydrotherapy may be a helpful first line treatment in terms of reduction of pain and improvement in function following injury, in addition to the evidence suggesting benefit in reducing chronic indications caused by acute or chronic stress. These findings add human evidence that helps define the outcomes that did and did not change with molecular hydrogen in this study.
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