Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
This in vitro or cellular study examined PGC-1α attenuates hydrogen peroxide-induced apoptotic cell death by upregulating Nrf-2 via GSK3β inactivation mediated by activated p38 in HK-2 Cells. The abstract describes Cell culture / in vitro model. The abstract reports: Using inhibitor of…
Read ArticleIn a laboratory model, electrolyzed Reduced Water (ERW) produced near the cathode during water electrolysis exhibits high pH, high concentration of dissolved hydrogen and an extremely negative redox…
Read ArticleIn a laboratory model, examined the neuroprotective effects of molecular hydrogen and Pt NPs and showed that both molecular hydrogen and Pt NPs contributed to the neuroprotective effects…
Read ArticleIn a laboratory model, H₂ solely reduced mitochondrial membrane potential of the cultured cells by 11.3% as assessed by TMRE. These findings from a laboratory model add evidence…
Read ArticleIn contrast, bile production and lactate dehydrogenase leakage therein were both significantly improved in HyFACS-HA and -PV + HA (P < 0.01), representing the superiority of the arterial…
Read ArticleIn What's more, HHW ameliorated lipid accumulation by regulating miR-136/MEG3/Nrf2 axis in vitro and in vivo, miR-136 was downregulated, MEG3 as well as Nrf2 was upregulated and serum…
Read Articlein vitro production of both TNF-alpha and IFN-gamma by ConA-stimulated spleen lymphocytes was significantly inhibited by the introduction of H(2), systemic antibiotics significantly decreased the level of H(2)…
Read ArticleIn a laboratory model, hydrogen water with high dissolved hydrogen molecule showed the same hepatocellular protective effect against ethanol as the EHW. The authors concluded that these results…
Read ArticleIn This study utilized an in vitro model of hepatocyte lipid accumulation induced by free fatty acids (FFAs) to replicate MASLD in HepG2 cells, as shown in Figure…
Read ArticleIn Recent studies have indicated H₂ can be used as a novel antioxidant to protect cells, decreased FtL and FtH protein expression level to 73% and 62% respectively…
Read ArticleIn a laboratory model, hydrogen has antioxidant and anti-inflammatory properties that can reduce the effects of ischemic injury. These findings from a laboratory model add evidence about molecular…
Read ArticleIn a laboratory model, an experimental circuit is assembled to validate the sensitivity and accuracy of the hydrogen monitoring system (Pureron Japan Co., Ltd) through in vitro investigations…
Read ArticleIn In the present study, various concentrations (0, 50 and 100 mg/l) of oxidized low-density lipoprotein (ox-LDL) were used to treat RAW264.7 cells, hydrogen has been demonstrated to…
Read ArticleIn Reactive oxygen species (ROS) are highly reactive and directly attack surrounding biomolecules to deteriorate cellular and tissue functions, meanwhile, ROS also serve as signaling mediators to upregulate…
Read ArticleIn Inflammation in male C57/BL6J mice or RAW264.7 cells was induced with LPS, for which hydrogen was immediately administered until samples were taken, hydrogen alleviated LPS-induced inflammatory infiltration…
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