Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In rats, hydrogen concentrations in the same tissue showed a dose-dependent response. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in this model.
Read ArticleIn an animal model, taken together, the results suggested that HRW treatment delayed softening and extended shelf life in postharvest okras through modifying cell wall biosynthesis and disassembly…
Read ArticleThe results show that hydrogen-rich saline treatment markedly increased the survival rate and neurological score, increased neuron survival, downregulated the autophagy protein expression of Beclin-1 and LC3, and…
Read ArticleRe: Preventive Effect of Hydrogen Water on the Development of Detrusor Overactivity in a Rat Model of Bladder Outlet Obstruction: N. Miyazaki, O. Yamaguchi, M.
Read ArticleThis preclinical study evaluated molecular hydrogen in rats. These results are preclinical and suggest molecular hydrogen's therapeutic potential in the condition studied. Further human research is needed to…
Read ArticleIn male Sprague-Dawley rats, inhalation of hydrogen (2.5%) markedly reduced the level of serum BUN, CREA and MDA (P < 0.05). These preclinical findings add evidence supporting molecular…
Read ArticleIn Sprague-Dawley rats, both alcohol dehydrogenase type 1 and acetaldehyde dehydrogenase related with oxidation of alcohol were significantly increased in liver tissue while the level of aspartate aminotransferase…
Read ArticleIn mice, the H₂ saturation concentrations varied among tissues significantly regardless of the concentration of H₂ inhaled, and they were detected the highest in the kidney but the…
Read ArticleIn rats, hRS reduced oxidative stress and improved myocardial collagen content, which may be related to inhibition of the TGF-β signaling pathway. These preclinical findings add evidence supporting…
Read ArticleIn the present study, the body weight and 13 serum biochemical parameters were monitored during the six-month hydrogen intervention, all these parameters were significantly altered by oral intake…
Read ArticleIn a complete Freund's Adjuvant-induced RA mouse model, this controlled hydrogen release behavior significantly downregulated pro-inflammatory mediators, protecting chondrocytes from apoptosis and preventing cartilage degradation. These preclinical findings…
Read ArticleIn mice, to clarify the mechanism of hydrogen's effect in the brain, the researchers administered hydrogen-rich pure water (H(2)) to senescence marker protein-30 (SMP30)/gluconolactonase (GNL) knockout (KO) mice,…
Read ArticleIn male Sprague-Dawley rats, hydrogen which may contribute to reduce rCklf1 expression prevents infiltration of inflammation and expression of MMP2 thus decreasing destruction and degradation of elastic fibers,…
Read ArticleIn rats, compared with PHN group,the rats in the PHN-H₂ group and PHN-H₂-Rap group showed increased PWT,decreased levels of TNF-α,IL-1β and IL-6,further up-regulated expressions of LC3 and beclin…
Read ArticleThe results demonstrate that H(2) treatment is beneficial to ouabain-induced AN via reducing apoptosis. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and…
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