Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In an animal model, the mechanism by which hydrogen gas alleviates TBI may be related to inhibiting NLRP3 inflammasomes in the cerebral cortex of rats. These preclinical findings add evidence about the molecular-hydrogen effects, outcomes, and biological pathways measured in this model.
Read ArticleIn rats, compared with CIH group, the pathology of liver microstructure were significantly improved and the serum levels of ALT, AST were significantly lower in H₂+CIH group (P<0.05);…
Read ArticleIn mice, exogenous H₂ reprograms colonocyte metabolism by regulating the H₂-gut microbiota-SCFAs axis and strengthens the intestinal barrier by modulating specific mucosa-associated mucolytic bacteria, wherein improved microbial hydrogen…
Read ArticleIn mice, it was also found that compared with the HRS group, overexpression of calpain1 increased caspase-3 activities, promoted cleaved-caspase3 and Bax protein expressions, and correspondingly decreased Bcl-2,…
Read ArticleIn mice, similarly, decreased tumor growth and cell proliferation, and enhanced cellular apoptosis were observed in H₂‑treated HeLa tumors. These preclinical findings add evidence supporting molecular hydrogen's therapeutic…
Read ArticleIn C57BL/6 mice, exposure to saturated H₂ (1.6 mg/L) 38 rapidly increased cytoplasmic Ca 2+ concentration (Figure 1 A), reaching a peak within 30 s (F/F 0 =…
Read ArticleIn mice, figure 1 Hydrogen reduced infarct volume, alleviated brain edema and improved neurobehavioral deficits at 24 hours after middle cerebral artery occlusion in mice. These preclinical findings…
Read ArticleIn an animal model, hydrogen gas inhalation significantly decreased both oxidative stress and embryonic gene expression, thus preserving cardiac function in CM hamsters. These preclinical findings add evidence…
Read ArticleIn mice, cS exposure significantly decreased plasma HDL cholesterol level (HDL-C) by 22% and increased LDL cholesterol level (LDL-C) by 21% compared with the control group (p <…
Read ArticleIn rats, H₂, Pt NPs and their combination significantly suppressed the levels of fasting blood glucose and improved the impaired sugar tolerance abilities of obese insulin-resistant type 2…
Read ArticleIn male Sprague-Dawley rats, cO poisoning resulted in increased levels of malondialdehyde, 3-nitrotyrosine and 8-hydroxy-2-deoxyguanosine and markedly reduced superoxide dismutase activity at 1 and 9 days, which were…
Read ArticleIn mice, after the treatment of saturated hydrogen, the changes in lung microbial population, lung tissue infiltration of inflammatory cells and the transformation of epithelial stroma caused by…
Read ArticleIn rats, hydrogen gas inhalation markedly suppressed mental retardation and cerebral palsy outcomes in rats at the juvenile developmental stage. These preclinical findings add evidence supporting molecular hydrogen's…
Read ArticleIn an animal model, although the effect of hydrogen gas on pathological findings was not obvious, the release of degraded DNA from the kidney, an acute marker of…
Read ArticleIn an animal model, 6 Another study demonstrated that hydrogen-rich water improved Parkinson’s disease. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and…
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