Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In rats, hydrogen inhalation significantly reduced the number of inflammatory cells in the bronchoalveolar lavage fluid, and the mRNA and protein expression levels of tumor necrosis factor alpha, IL-6, IL-17, IL-23, matrix metalloproteinase-12, caspase-3, and caspase-8, but increased the tissue inhibitor of…
Read ArticleIn mice, hydrogen gas inhalation markedly upregulated the activity of decreased superoxide dismutase and significantly attenuated the increased level of malondialdehyde and myeloperoxidase. These preclinical findings add evidence…
Read ArticleIn an animal model, administration of H₂-rich water attenuated the CS-induced lung damage in the SMP30-KO mice and reduced the mean linear intercept and destructive index of the…
Read ArticleIn mice, combination treatment with inhaled NO and H₂ could also significantly attenuate lung injury in polymicrobial sepsis. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential…
Read ArticleIn mice, showed that 66.7 % hydrogen alleviated lung pathological changes and pulmonary edema caused by LPS, and reduced the degree of ALI by inhibiting pro-inflammatory cytokine release…
Read ArticleIn an animal model, however, BLM-induced oxidative stress was attenuated by H₂ inhalation therapy, which reduced the contents of reactive oxygen species, malondialdehyde and hydroxyproline, enhanced the activity…
Read ArticleIn rats, compared to the sham group (A), germ cellular apoptosis and lipid peroxidation in the ischemia group (B) were significantly increased with abnormal morphology and impaired spermatogenesis.…
Read ArticleIn rats, hydrogen rich saline solution treatment significantly decreased the apoptosis index. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways…
Read ArticleIn mice, serum testosterone and FSH levels also increased, while serum ROS level decreased (all P <0.05). These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within…
Read ArticleIn mice, this study demonstrates that treating mice with H₂ before ionizing radiation (IR) can increase the spermatid head count and protect seminiferous epithelium from IR. These results…
Read ArticleThe results first demonstrated that long-term treatment with hydrogen-rich saline attenuated testicular oxidative level and improved male reproductive function in nicotine-treated mice. These preclinical findings add evidence supporting…
Read ArticleIn rats, although placental weight and the number of fetuses had no significant difference among groups, the placental efficiency significantly increased after the oral administration of HRW to…
Read ArticleIn rats, follicular injury, edema, vascular congestion, loss of cohesion and apoptotic index were higher in the torsion groups but decreased in the groups that received HRSS. These…
Read ArticleIn female BALB/c mice, the GC AI was significantly higher in the model group (21.30 ± 1.74%) than those in the control (7.06 ± 0.27%), hydrogen (5.17 ±…
Read ArticleIn HRW treatment of POF rats, the serum AMH and E2 levels significantly increased, and FSH level significantly reduced, indicating the protective role of HRW. These preclinical findings…
Read Article