Hydrogen-rich solution attenuates cold ischemia-reperfusion injury in rat liver transplantation.
This animal study examined Hydrogen-rich solution attenuates cold ischemia-reperfusion injury in rat liver transplantation. The abstract describes Rat model; hydrogen delivered as hydrogen water and injected or infused hydrogen. The abstract reports: Storage of liver grafts in hydrogen-rich UW solution resulted in superior functional and morphologic protection against IRI via the up-regulation of HO-1 expression. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHepatoprotective effect of electrolyzed reduced water against carbon tetrachloride-induced liver damage in mice.
This animal study examined Hepatoprotective effect of electrolyzed reduced water against carbon tetrachloride-induced liver damage in mice. The abstract describes Mouse model. The abstract reports: Therefore, the results of this study show that ERW can be proposed to protect the liver against CCl(4)-induced oxidative damage in mice, and the…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich water prevents progression of nonalcoholic steatohepatitis and accompanying hepatocarcinogenesis in mice.
This animal study examined Hydrogen-rich water prevents progression of nonalcoholic steatohepatitis and accompanying hepatocarcinogenesis in mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water; reported duration 8 weeks. The abstract reports: Consumption of hydrogen-rich water may be an effective treatment for NASH by reducing hepatic oxidative stress, apoptosis, inflammation, and hepatocarcinogenesis. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhalation of molecular hydrogen prevents ischemia-reperfusion liver damage during major liver resection.
This animal study examined Inhalation of molecular hydrogen prevents ischemia-reperfusion liver damage during major liver resection. The abstract describes Porcine model; hydrogen delivered as hydrogen inhalation; reported duration 120 minutes. The abstract reports: In this experimental study, we showed that inhaled hydrogen during major liver resection unquestionably reduced the level of oxidative stress associated with ischemia-reperfusion damage.…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen attenuates hypoxia/reoxygenation injury of intrahepatic cholangiocytes by activating Nrf2 expression.
This animal study examined Molecular hydrogen attenuates hypoxia/reoxygenation injury of intrahepatic cholangiocytes by activating Nrf2 expression. The abstract describes Rat model. The abstract reports: We found that H2 ameliorated H/R-induced cholangiocytes apoptosis. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreAnti-inflammatory properties of molecular hydrogen: investigation on parasite-induced liver inflammation.
This animal study examined Anti-inflammatory properties of molecular hydrogen: investigation on parasite-induced liver inflammation. The abstract describes Mouse model. The abstract reports: It has been suggested therefore to use gaseous hydrogen in a new anti-inflammatory strategy. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreAnti-oxidant and anti-inflammatory effects of hydrogen-rich water alleviate ethanol-induced fatty liver in mice.
This animal study examined Anti-oxidant and anti-inflammatory effects of hydrogen-rich water alleviate ethanol-induced fatty liver in mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: HRW protects against chronic EtOH-induced liver injury, possibly by inducing acyl ghrelin to suppress the pro-inflammatory cytokines TNF-α and IL-6 and induce IL-10 and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreLong-term consumption of hydrogen-rich water provides hepatoprotection by improving mitochondrial biology and quality control in chronically stressed mice.
This animal study examined Long-term consumption of hydrogen-rich water provides hepatoprotection by improving mitochondrial biology and quality control in chronically stressed mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: This study reveals that long-term hydrogen-rich water (HRW) consumption provides significant hepatoprotection in mice under chronic stress. HRW normalizes liver enzyme levels, enhances antioxidant…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreLong-Term Consumption of Hydrogen-Rich Water Mitigates Oxidative Stress, Hepatic Inflammation, and Apoptosis in Rats with LPS-Induced Chronic Liver Injury.
This animal study examined Long-Term Consumption of Hydrogen-Rich Water Mitigates Oxidative Stress, Hepatic Inflammation, and Apoptosis in Rats with LPS-Induced Chronic Liver Injury. The abstract describes Rat model; hydrogen delivered as hydrogen water; reported duration 8 months. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas (H) delivered by intraperitoneal injection alleviated methionine- and choline-deficient diet-induced metabolic dysfunction-associated steatotic liver disease in mice via inhibiting GSDMD- and GSDME-mediated pyroptosis.
This animal study examined Hydrogen gas (H) delivered by intraperitoneal injection alleviated methionine- and choline-deficient diet-induced metabolic dysfunction-associated steatotic liver disease in mice via inhibiting GSDMD- and GSDME-mediated pyroptosis. The abstract describes Mouse model; hydrogen delivered as injected or infused hydrogen. The abstract reports: H is an anti-pyroptosis gas molecule, intraperitoneal injection of H is a novel therapeutic strategy for MASLD that deserves further investigation. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreA Novel Antioxidant, Hydrogen-Rich Coral Calcium Alters Gut Microbiome and Bile Acid Synthesis to Improve Methionine-and-Choline-Deficient Diet-Induced Non-Alcoholic Fatty Liver Disease.
This animal study examined A Novel Antioxidant, Hydrogen-Rich Coral Calcium Alters Gut Microbiome and Bile Acid Synthesis to Improve Methionine-and-Choline-Deficient Diet-Induced Non-Alcoholic Fatty Liver Disease. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: In the present study, we found that HRCC treatment improved methionine-and-choline-deficient diet (MCD)-induced hepatic steatosis, increased aspartate aminotransferase and alanine aminotransferase levels, and elevated…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas ameliorates acute alcoholic liver injury via anti-inflammatory and antioxidant effects and regulation of intestinal microbiota.
This animal study examined Hydrogen gas ameliorates acute alcoholic liver injury via anti-inflammatory and antioxidant effects and regulation of intestinal microbiota. The abstract describes Mouse model. The abstract reports: Hydrogen gas (H) has been demonstrated to be an efficient antioxidant in various diseases in animals as well as humans. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas alleviates acute ethanol-induced hepatotoxicity in mice via modulating TLR4/9 innate immune signaling and pyroptosis.
This animal study examined Hydrogen gas alleviates acute ethanol-induced hepatotoxicity in mice via modulating TLR4/9 innate immune signaling and pyroptosis. The abstract describes Mouse model. The abstract reports: Our results showed that intraperitoneal injection of H improved acute ethanol-induced liver injury in mice in a dose dependent manner, as indicated by decreasing…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreLong-term and daily use of molecular hydrogen induces reprogramming of liver metabolism in rats by modulating NADP/NADPH redox pathways.
This animal study examined Long-term and daily use of molecular hydrogen induces reprogramming of liver metabolism in rats by modulating NADP/NADPH redox pathways. The abstract describes Rat model. The abstract reports: Rats exposed 2 h daily to H either by drinking HRW (H dissolved in HO) or by breathing 4% H gas showed reduced lipogenesis and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreA strategy of local hydrogen capture and catalytic hydrogenation for enhanced therapy of chronic liver diseases.
This animal study examined A strategy of local hydrogen capture and catalytic hydrogenation for enhanced therapy of chronic liver diseases. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. This is an automated editorial draft based on the abstract and requires source review before publication.
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