Protective effects of hydrogen enriched saline on liver ischemia reperfusion injury by reducing oxidative stress and HMGB1 release.
This animal study examined Protective effects of hydrogen enriched saline on liver ischemia reperfusion injury by reducing oxidative stress and HMGB1 release. The abstract describes Rat model; hydrogen delivered as injected or infused hydrogen. The abstract reports: These results suggest that, in our model, hydrogen enriched saline treatment is protective against liver ischemia-reperfusion injury. This effect may be mediated by both…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe protective role of hydrogen-rich saline in experimental liver injury in mice.
This animal study examined The protective role of hydrogen-rich saline in experimental liver injury in mice. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: HS could protect against liver injury and also inhibit the processes leading to liver cirrhosis and hepatocyte compensatory proliferation. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInfluence of Hydrogen-rich Saline on Hepatocyte Autophagy During Laparoscopic Liver Ischaemia-reperfusion Combined Resection Injury in Miniature Pigs.
This animal study examined Influence of Hydrogen-rich Saline on Hepatocyte Autophagy During Laparoscopic Liver Ischaemia-reperfusion Combined Resection Injury in Miniature Pigs. The abstract describes Animal model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Intervention with hydrogen-rich saline could exert a protective effect against liver ischaemia-reperfusion combined resection injury through the reduction of oxidative stress and hepatocyte autophagy. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhalation of high concentrations of hydrogen ameliorates liver ischemia/reperfusion injury through A2A receptor mediated PI3K-Akt pathway
This animal study examined Inhalation of high concentrations of hydrogen ameliorates liver ischemia/reperfusion injury through A2A receptor mediated PI3K-Akt pathway. The abstract describes Mouse model; sample size 6. The abstract reports: Our findings indicate that HCH may protect the liver against I/R injury through the A dependent PI3K-Akt pathway. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffect of hydrogen-rich saline on apoptosis induced by hepatic ischemia reperfusion upon laparoscopic hepatectomy in miniature pigs.
This animal study examined Effect of hydrogen-rich saline on apoptosis induced by hepatic ischemia reperfusion upon laparoscopic hepatectomy in miniature pigs. The abstract describes Animal model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The results showed that HRS treatment significantly decreased serum levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST) and total bilirubin (TBIL) activity and TUNEL-positive…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Gas Ameliorates Hepatic Reperfusion Injury After Prolonged Cold Preservation in Isolated Perfused Rat Liver.
This animal study examined Hydrogen Gas Ameliorates Hepatic Reperfusion Injury After Prolonged Cold Preservation in Isolated Perfused Rat Liver. The abstract describes Rat model; reported duration 90 min. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of oral intake of hydrogen water on liver fibrogenesis in mice.
This animal study examined Effects of oral intake of hydrogen water on liver fibrogenesis in mice. The abstract describes Mouse model; sample size 6; hydrogen delivered as hydrogen water. The abstract reports: We conclude that hydrogen water protects hepatocytes from injury by scavenging hydroxyl radicals and thereby suppresses liver fibrogenesis in mice. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-Rich Saline Ameliorates Hepatic Ischemia-Reperfusion Injury Through Regulation of Endoplasmic Reticulum Stress and Apoptosis.
This animal study examined Hydrogen-Rich Saline Ameliorates Hepatic Ischemia-Reperfusion Injury Through Regulation of Endoplasmic Reticulum Stress and Apoptosis. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The protective effect of HS can be attributed to ER stress and apoptosis inhibition. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreSaturated hydrogen saline attenuates endotoxin-induced acute liver dysfunction in rats.
This animal study examined Saturated hydrogen saline attenuates endotoxin-induced acute liver dysfunction in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas inhalation attenuates sepsis-induced liver injury in a FUNDC1-dependent manner.
This animal study examined Hydrogen gas inhalation attenuates sepsis-induced liver injury in a FUNDC1-dependent manner. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: We have demonstrated that hydrogen gas (H), a selective antioxidant, exerts protective effects in septic mice. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreIntake of Molecular Hydrogen in Drinking Water Increases Membrane Transporters, -Glycoprotein, and Multidrug Resistance-Associated Protein 2 without Affecting Xenobiotic-Metabolizing Enzymes in Rat Liver.
This animal study examined Intake of Molecular Hydrogen in Drinking Water Increases Membrane Transporters, -Glycoprotein, and Multidrug Resistance-Associated Protein 2 without Affecting Xenobiotic-Metabolizing Enzymes in Rat Liver. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: The results showed that intake of HRW had no significant effect on the activities of various cytochrome P450 (CYP) enzymes (CYP1A1, 1A2, 2B, 2C,…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHepatic oxidoreduction-related genes are upregulated by administration of hydrogen-saturated drinking water.
This animal study examined Hepatic oxidoreduction-related genes are upregulated by administration of hydrogen-saturated drinking water. The abstract describes Rat model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of alkaline-electrolyzed and hydrogen-rich water, in a high-fat-diet nonalcoholic fatty liver disease mouse model
This animal study examined Effects of alkaline-electrolyzed and hydrogen-rich water, in a high-fat-diet nonalcoholic fatty liver disease mouse model. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: We hypothesized that the null result was due to low H concentrations. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen accelerates the reversal of acute obstructive cholangitis‑induced liver dysfunction by restoring gap and tight junctions.
This animal study examined Molecular hydrogen accelerates the reversal of acute obstructive cholangitis‑induced liver dysfunction by restoring gap and tight junctions. The abstract describes Rat model. The abstract reports: The mechanism of this phenomenon suggests that H2 may have effectively attenuated AOC‑induced inflammatory and oxidative damage, and decreased matrix metalloproteinase activity. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich solution attenuates cold ischemia-reperfusion injury in rat liver transplantation.
This animal study examined Hydrogen-rich solution attenuates cold ischemia-reperfusion injury in rat liver transplantation. The abstract describes Rat model; hydrogen delivered as hydrogen water and injected or infused hydrogen. The abstract reports: Storage of liver grafts in hydrogen-rich UW solution resulted in superior functional and morphologic protection against IRI via the up-regulation of HO-1 expression. This is an automated editorial draft based on the abstract and requires source review before publication.
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