Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In rats, administration of hydrogen-rich saline or edaravone dramatically reduced the pulmonary levels of pulmonary inflammation mediators and myeloperoxidase. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in this model.
Read ArticleIn mice, these results demonstrate that molecular hydrogen treatment ameliorates LPS-induced ALI through reducing lung inflammation and apoptosis, which may be associated with the decreased NF-κB activity. These…
Read ArticleThis preclinical study evaluated molecular hydrogen in rats. These results are preclinical and suggest molecular hydrogen's therapeutic potential in the condition studied. Further human research is needed to…
Read ArticleIn rats, hydrogen-rich saline improved the survival rate and attenuated pulmonary edema, injury, and apoptosis. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes…
Read ArticleIn an animal model, hydrogen could significantly reduce HALI by reducing lung edema and apoptosis, inhibiting the elevating of ERS and increased SIRT1 expression. These preclinical findings add…
Read ArticleIn male Sprague-Dawley rats, hydrogen saline significantly protected vasoactivity of the pulmonary artery, reduced pulmonary oedema, decreased lung malondialdehyde (MDA), 8-OHdG concentration, alleviated lung epithelial cellular apoptosis and…
Read ArticleIn rats, however, after treatment with HSS, all of these changes were alleviated (P < 0.05), and these changes were mitigated when treated with HSS by ip then…
Read ArticleIn rats, hyperoxia exposure increased glutathione content in lung homogenate (36%) more than hyperoxia+H₂ (21%), consistent with increases measured in Tc-HMPAO lung uptake. These preclinical findings add evidence…
Read ArticleIn rats, exposure to 1.3% hydrogen significantly attenuated the upregulation of the messenger RNAs for several proinflammatory mediators induced by HS/R. Hydrogen inhalation did not affect hemodynamic status…
Read ArticleIn male Sprague-Dawley rats, treatment with saturated hydrogen saline prolonged the median survival time of rats and reduced lung dysfunction induced by LPS. These preclinical findings add evidence…
Read ArticleIn mice, hydrogen-rich water treatment at doses of 2.5, 5, or 10 ml/kg significantly attenuated LPS-induced pulmonary fibrosis. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential…
Read ArticleThe results indicated that PaO2, PaCO2, and T-SOD increased in the three treatment groups (P < 0.05), most significantly in the HOHS group (P < 0.01) compared with…
Read ArticleIn rats, at P1, LPS treatment decreased expressions of genes for FGFR4, VEGFR2, and HO-1 in the lungs, and hydrogen increased expressions of these genes. These preclinical findings…
Read ArticleIn male Sprague-Dawley rats, hydrogen water consumption reduced wet-to-dry weight ratio, malondialdehyde and myeloperoxidase activity and decreased the concentration of TNF-α, IL-1β, and IL-6 in the lung tissues…
Read ArticleIn male Sprague-Dawley rats, as shown in Figure 6B, the Nrf2 protein level increased significantly in the CS-challenged rat lungs as compared with that in the control (p<0.01),…
Read Article