Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In male Sprague-Dawley rats, hRS or HBO2 single treatment could decrease inflammatory cytokine release in lung tissue, reduce the accumulation of oxidative products and alleviate apoptosis of pulmonary cells, then lead to positive therapeutic effects on ALI induced by LPS. These preclinical…
Read ArticleIn mice, hydrogen inhalation increased the survival rate to 80%, reduced LPS-induced lung damage, and decreased inflammatory cytokine release in LPS mice. These preclinical findings add evidence supporting…
Read ArticleIn mice, e-cadherin and ZO-1 levels in airway tissues of asthmatic mice were significantly lower than that of control mice, and the reduction was recovered by H₂ treatment.…
Read ArticleIn an animal model, hydrogen significantly improved the survival rate of mice, reduced pulmonary edema and hemorrhage, infiltration of neutrophils, and IL-6 secretion. These preclinical findings add evidence…
Read ArticleThe results suggest that hydrogen inhalation inhibits the deterioration of respiratory physiological function and alveolar fibrosis in this model of lung injury. These preclinical findings add evidence supporting…
Read ArticleIn rats, however, these variables were significantly improved in the cold ischemia with hydrogen-rich preservation solution group. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within…
Read ArticleIn Sprague Dawley rats, antenatal H₂ administration may decrease the pulmonary mobility associated with inflammation in premature infants. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential…
Read ArticleIn mice, the light microscope findings showed that saturated hydrogen saline reduced the impairment when compared with the saline group: Saturated hydrogen saline decreased lung edema, reduced LDH…
Read ArticleIn an animal model, hydrogen treatment during exposure to hyperoxia significantly improved blood oxygenation, reduced inflammatory events, and induced HO-1 expression. These preclinical findings add evidence supporting molecular…
Read ArticleIn mice, hydrogen gas did not alleviate LPS-induced liver injury under the conditions tested. These results are preclinical and suggest that molecular hydrogen did not improve the measured…
Read ArticleIn rats, after IRI, pulmonary function (pulmonary compliance and oxygenation levels) was significantly higher in the hydrogen-rich saline group than in the normal saline group ( P <…
Read ArticleIn an animal model, sepsis-challenged animals had decreased survival rate, as well as had increased bacterial burden in blood, peritoneal lavage, and lung sample, which were significantly ameliorated…
Read ArticleIn mice, hydrogen gas inhalation increased NFκB DNA binding after 1h of ventilation and decreased NFκB DNA binding after 2h of ventilation, as compared with controls. These preclinical…
Read ArticleIn mice, however, H₂ did not substantially affect the H/R-induced increase in erythropoietin or pulmonary artery remodeling. These preclinical findings add evidence about the molecular-hydrogen effects, outcomes, and…
Read ArticleIn male Sprague-Dawley rats, hRS administration significantly reduced the serum high-mobility group box, alanine aminotransferase, creatinine, and blood urea nitrogen levels. The pulmonary interleukin 6, high-mobility group box,…
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