Hydrogen-rich water protects against liver injury in nonalcoholic steatohepatitis through HO-1 enhancement via IL-10 and Sirt 1 signaling.

This in vitro or cellular study examined Hydrogen-rich water protects against liver injury in nonalcoholic steatohepatitis through HO-1 enhancement via IL-10 and Sirt 1 signaling. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effect of hydrogen-rich water against gentamicin-induced nephrotoxicity in rats using blood oxygenation level-dependent MR imaging.

This animal study examined Protective effect of hydrogen-rich water against gentamicin-induced nephrotoxicity in rats using blood oxygenation level-dependent MR imaging. The abstract describes Rat model; hydrogen delivered as hydrogen water and injected or infused hydrogen; reported duration 7 days. The abstract reports: Our findings suggested reduced oxygen utility, mainly in the cortex, in gentamicin-induced nephrotoxicity and an ameliorative effect of hydrogen-rich water against GIN. This is an automated editorial draft based on the abstract and requires source review before publication.

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Dissolved molecular hydrogen (H) in Peritoneal Dialysis (PD) solutions preserves mesothelial cells and peritoneal membrane integrity.

This uncontrolled human study examined Dissolved molecular hydrogen (H) in Peritoneal Dialysis (PD) solutions preserves mesothelial cells and peritoneal membrane integrity. The abstract describes Human participants. The abstract reports: H-dissolved PD solutions could preserve mesothelial cells and peritoneal membrane integrity in PD rats. Clinical application of H in PD could be a novel…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas inhalation ameliorates glomerular enlargement after hypoxic-ischemic insult in asphyxiated piglet model.

This animal study examined Hydrogen gas inhalation ameliorates glomerular enlargement after hypoxic-ischemic insult in asphyxiated piglet model. The abstract describes Porcine model; hydrogen delivered as hydrogen inhalation. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effects of hydrogen-rich saline against renal ischemia-reperfusion injury by increased expression of heme oxygenase-1 in aged rats.

This animal study examined Protective effects of hydrogen-rich saline against renal ischemia-reperfusion injury by increased expression of heme oxygenase-1 in aged rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: HRS improves the renal response to I/R in aged rats, possibly by reducing oxidative stress and upregulating HO-1 gene expression. This is an automated editorial draft based on the abstract and requires source review before publication.

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Prevention of Chronic Rejection of Marginal Kidney Graft by Using a Hydrogen Gas-Containing Preservation Solution and Adequate Immunosuppression in a Miniature Pig Model

This animal study examined Prevention of Chronic Rejection of Marginal Kidney Graft by Using a Hydrogen Gas-Containing Preservation Solution and Adequate Immunosuppression in a Miniature Pig Model. The abstract describes Porcine model. The abstract reports: A few cases showed chronic rejection reaction; however, most were found to be free of chronic rejection such as graft tissue fibrosis or renal…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Organ preservation solution containing dissolved hydrogen gas from a hydrogen-absorbing alloy canister improves function of transplanted ischemic kidneys in miniature pigs.

This animal study examined Organ preservation solution containing dissolved hydrogen gas from a hydrogen-absorbing alloy canister improves function of transplanted ischemic kidneys in miniature pigs. The abstract describes Porcine model; hydrogen delivered as injected or infused hydrogen; reported duration 4 hours. This is an automated editorial draft based on the abstract and requires source review before publication.

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UPLC/MS-Based Metabolomics Investigation of the Protective Effect of Hydrogen Gas Inhalation on Mice with Calcium Oxalate-Induced Renal Injury.

This animal study examined UPLC/MS-Based Metabolomics Investigation of the Protective Effect of Hydrogen Gas Inhalation on Mice with Calcium Oxalate-Induced Renal Injury. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: This study showed the effects of hydrogen on serum and urine metabolites in a renal injury model. This is an automated editorial draft based on the abstract and requires source review before publication.

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Aerosol inhalation of a hydrogen-rich solution restored septic renal function.

This animal study examined Aerosol inhalation of a hydrogen-rich solution restored septic renal function. The abstract describes Mouse model; hydrogen delivered as injected or infused hydrogen. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen protects against chronic intermittent hypoxia induced renal dysfunction by promoting autophagy and alleviating apoptosis.

This animal study examined Hydrogen protects against chronic intermittent hypoxia induced renal dysfunction by promoting autophagy and alleviating apoptosis. The abstract describes Rat model. The abstract reports: We demonstrated that rats who inhale hydrogen gas showed improved renal function, alleviated pathological damage, oxidative stress and apoptosis in CIH rats. Meanwhile, CIH-induced…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-Rich Saline Promotes the Recovery of Renal Function after Ischemia/Reperfusion Injury in Rats via Anti-apoptosis and Anti-inflammation.

This animal study examined Hydrogen-Rich Saline Promotes the Recovery of Renal Function after Ischemia/Reperfusion Injury in Rats via Anti-apoptosis and Anti-inflammation. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: HRSS showed a protective effect in the prevention of renal injury and could promote renal function recovery after I/R injury in rats. HRSS might…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Oral hydrogen water prevents chronic allograft nephropathy in rats.

This animal study examined Oral hydrogen water prevents chronic allograft nephropathy in rats. The abstract describes Rat model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline attenuates acute renal injury in sodium taurocholate-induced severe acute pancreatitis by inhibiting ROS and NF-κB pathway.

This animal study examined Hydrogen-rich saline attenuates acute renal injury in sodium taurocholate-induced severe acute pancreatitis by inhibiting ROS and NF-κB pathway. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Results showed that hydrogen-rich saline attenuated the following: (1) serum Cr and BUN, (2) pancreatic and renal pathological injuries, (3) renal MDA, (4) renal…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen Gas Alleviates Chronic Intermittent Hypoxia-Induced Renal Injury through Reducing Iron Overload.

This in vitro or cellular study examined Hydrogen Gas Alleviates Chronic Intermittent Hypoxia-Induced Renal Injury through Reducing Iron Overload. The abstract describes Epithelial cell model. The abstract reports: Iron-induced oxidative stress has been found to be a central player in the pathogenesis of kidney injury. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline ameliorates renal injury induced by unilateral ureteral obstruction in rats.

This animal study examined Hydrogen-rich saline ameliorates renal injury induced by unilateral ureteral obstruction in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline; reported duration 10 days. The abstract reports: Hydrogen has been demonstrated to have effective protection against tissue injuries caused by oxidative stress, inflammation, and apoptosis. This is an automated editorial draft based on the abstract and requires source review before publication.

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