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755 Articles

Comprehensive brain tissue metabolomics and biological network technology to decipher the mechanism of hydrogen-rich water on Radiation-induced cognitive impairment in rats.

By H2HUBB Jul 22, 2026 0 Comments

In rats, the study has systematically elucidated the molecular mechanism of HRW against ionizing radiation, which can be mediated by modulating targets, pathways and metabolite levels. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways…

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Effect of Hydrogen-Rich Water on Radiation-Induced Cognitive Dysfunction in Rats.

By H2HUBB Jul 22, 2026 0 Comments

In rats, compared to the radiation treated group, the radiation-HRW treated group showed significantly decreased escape latency (P < 0.05), but increased retention time, swimming distance of original…

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Drinking Hydrogen-Rich Water Alleviates Chemotherapy-Induced Neuropathic Pain Through the Regulation of Gut Microbiota.

By H2HUBB Jul 22, 2026 0 Comments

In mice, following treatment with oxaliplatin, the expression of inflammatory cytokines TNF-α and IL-6 was significantly increased (P<0.05, H₂O + OXA vs H₂O + Saline; P<0.05, HW +…

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Nephroprotective effect of electrolyzed reduced water against cisplatin-induced kidney toxicity and oxidative damage in mice.

By H2HUBB Jul 22, 2026 0 Comments

In an animal model, after administration of ERW, the reduced urinary osmolality was increased and elevated Na+, K+, Mg2+ and Ca2+ levels in urine were significantly decreased in…

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Hydrogen-rich saline protects against ultraviolet B radiation injury in rats.

By H2HUBB Jul 22, 2026 0 Comments

In female C57BL/6 rats, the group that received H₂-rich saline treatment showed a significant increased in SOD activities compared to the untreated irradiated group (51.81±5.67 vs 33.48±4.28, P…

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Protective effect of inhalation of hydrogen gas on radiation-induced dermatitis and skin injury in rats.

By H2HUBB Jul 22, 2026 0 Comments

In rats, it has previously been demonstrated that hydrogen gas selectively reduces cytotoxic ROS such as the hydroxyl radical [ 11, 16 ]. These preclinical findings add evidence…

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Hydrogen protects rats from dermatitis caused by local radiation.

By H2HUBB Jul 22, 2026 0 Comments

In rats, hydrogen significantly reduced the severity of dermatitis, accelerated tissue recovery, and reduced the extent of radiation-induced weight loss in rats after a single dose of 15…

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Regulation of microRNAs by molecular hydrogen contributes to the prevention of radiation-induced damage in the rat myocardium.

By H2HUBB Jul 22, 2026 0 Comments

In rats, treatment with molecular hydrogen-rich water (HRW) reduced these values to the level of non-irradiated controls. miRNA-1 is known to be involved in cardiac hypertrophy, and was…

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Hydrogen therapy attenuates irradiation-induced lung damage by reducing oxidative stress.

By H2HUBB Jul 22, 2026 0 Comments

In mice, within 1 wk after whole thorax irradiation, immunohistochemistry and immunoblotting showed that H(2) treatment reduced oxidative stress and apoptosis, measures of acute damage, in the lungs…

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The healing effect of hydrogen-rich water on acute radiation-induced skin injury in rats.

By H2HUBB Jul 22, 2026 0 Comments

In rats, the healing time was shortened in the two HRW-treated groups (P < 0.05). These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes…

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Hydrogen-water ameliorates radiation-induced gastrointestinal toxicity via MyD88’s effects on the gut microbiota.

By H2HUBB Jul 22, 2026 0 Comments

In mice, after exposure to 15 Gy TAI, the animal survival rate was decreased by 50% in the control vehicle group, but it was decreased by only 10%…

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Histological study on the effect of electrolyzed reduced water-bathing on UVB radiation-induced skin injury in hairless mice.

By H2HUBB Jul 22, 2026 0 Comments

In mice, further, the level of interleukin (IL)-1β, tumor necrosis factor (TNF)-α and IL-12p70 in ERW group decreased whereas those of IL-10 increased. These preclinical findings add evidence…

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Hydrogen Inhalation Protects against Ototoxicity Induced by Intravenous Cisplatin in the Guinea Pig.

By H2HUBB Jul 22, 2026 0 Comments

In guinea pigs, H₂ inhalation mitigated all these effects. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in this…

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Hydrogen-rich saline attenuates chemotherapy-induced ovarian injury via regulation of oxidative stress.

By H2HUBB Jul 22, 2026 0 Comments

In female Sprague Dawley rats, hydrogen-rich saline attenuated the FSH release, elevated the level of E2, improved the development of follicles, and reduced the damage to the ovarian…

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Mitigating radiation-induced brain injury via NLRP3/NLRC4/Caspase-1 pyroptosis pathway: Efficacy of memantine and hydrogen-rich water.

By H2HUBB Jul 22, 2026 0 Comments

In an animal model, particularly, hydrogen-rich water showed a promising reduction in these symptoms. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and…

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