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The results demonstrate that HRW significantly increased the average daily feed intake and significantly reduced the diarrhea rate in weaned piglets. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in this model.
Read ArticleIn guinea pigs, by Scanning electron microscopy and succinate dehydrogenase staining, the researchers found that pre-treatment with hydrogen-saturated saline significantly reduced noise-induced hair cell damage and hearing loss.…
Read ArticleIn rats, at 30 and 90 min, no significant difference among the experimental groups in the MAP or HR was observed, suggesting that the hydrogen-rich water had no…
Read ArticleIn mice, a significant increase of t-PA and decrease of TGF-b1 and PAI-1 in the peritoneal fluids were observed in the hydrogen-rich saline-treated groups. hydrogen-rich saline did not…
Read ArticleIn Sprague-Dawley rats, hydrogen-rich saline treatment decreased the blood and placental MDA, proteinuria and the pro-inflammatory cytokine TNF-α, IL-1β in the placental tissues compared with those in L-NAME-treated…
Read ArticleIn mice, these findings suggest that molecular hydrogen attenuates HFHSD-induced metabolic disturbances primarily through suppression of adipose inflammation. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential…
Read ArticleIn an animal model, compared with HRS, ALT and TBIL in ADSCs group were significantly decreased at 3 d, and AST was significantly reduced at 1 d. These…
Read ArticleIn rats, compared with N group, the percentage of time spent in the target quadrant and the frequency of crossing the platform of rats in T group were…
Read ArticleThe results of the H&E, and Nissl staining indicated that the CLP mice had a significant brain injury, which was characterized by aggravated pathological damage and was alleviated…
Read ArticleIn an animal model, HRW prevented the ischemia-induced reduction of parvalbumin and hippocalcin levels in vivo and also reduced the glutamate toxicity-induced death of neurons, including the dose-dependent…
Read ArticleIn rats, expression levels of MIP-1-alpha and ICAM-1 increased in the brains of CO-poisoned rats and H(2) rich saline treatment decreased the levels. These preclinical findings add evidence…
Read ArticleIn Wistar rats, after HS administration, all these parameters were considerably improved, and the characteristics of hSCI testes were similar to those of normal control testes. These preclinical…
Read ArticleIn rats, hydrogen (2.9%) administered concurrently with surgery significantly decreased the formation of cerebral edema (p = 0.028) and improved neurobehavioral score (p = 0.022). These preclinical findings…
Read ArticleIn rats, compared with hydrogen-rich saline treatment, hydrogen inhalation significantly reduced blood glucose levels in diabetic rats in the 4th and 8th weeks. These preclinical findings add evidence…
Read ArticleIn rats, HRW treatment decreased DAPI/PI/β‐PDGFR and β‐PDGFR/ROS‐positive cells while increasing the β‐PDGFR/SOD‐positive cells, indicating that HRW attenuated HI‐induced oxidative stress injury in pericytes (Figure 1B–D ). These…
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