Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In mice, molecular hydrogen is produced as a fermentation by-product in the large intestine of animals and its production can be correlated with the digestibility of the carbohydrates consumed. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes…
Read ArticleBody weight and number of peripheral blood cells were significantly improved for mice in the H₂-rich solution treated groups as compared with those with AA. These results are…
Read ArticleIn mice, there are several mechanisms of how H₂ protects neuronal damage. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways…
Read ArticleIn female C57BL/6 mice, at the molecular level, HRW reduced spinal oxidative stress and ERK-dependent plasticity without altering spinal NLRP3 expression, whereas it fully reversed NLRP3 upregulation and…
Read ArticleIn an animal model, consumption of hydrogen water ad libitum throughout the whole period suppressed the increase in the oxidative stress markers and prevented cognitive impairment, as judged…
Read ArticleIn pregnant mice fed a diet containing the Si-based agent, lipopolysaccharide (LPS)-induced miscarriage due to mother-to-child transmission was reduced and inflammation and neutrophil infiltration in the placenta were…
Read ArticleIn rats, H₂ significantly attenuated hydrogen peroxide-induced sFlt-1 expression, but could not reduce the expression induced by hypoxia in BeWo cells. These preclinical findings add evidence supporting molecular…
Read ArticleIn rats, concluded that HRW protects the neurons against lead-induced oxidative stress and has anti-apoptotic effects without a noticeable change in NO level which already was diminished by…
Read ArticleIn mice, plasma creatine kinase activities were decreased by hydrogen at ages 10 and 24 weeks. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the…
Read ArticleIn mice, the authors' recent studies provided evidence that hydrogen inhalation can selectively reduce cytotoxic oxygen radicals and exert antioxidant effects. These preclinical findings add evidence supporting molecular…
Read ArticleIn male Wistar rats, each hydrogen-rich liquid resuscitation preparation could protect the lung against acute injury secondary to UHS. These preclinical findings add evidence supporting molecular hydrogen's therapeutic…
Read ArticleIn an animal model, aBR thresholds were significantly lower in H₂-treated animals at 2 weeks after exposure, with significant preservation of outer hair cells in the entire cochlea.…
Read ArticleThe researchers found that hydrogen is available in the gastric mucosa of mice and that its use greatly increased the stomach colonization by H. pylori. These preclinical findings…
Read ArticleIn Sprague-Dawley rats, prenatal H₂ administration improved respiratory function by attenuating lung morphology and pulmonary artery thickening in CDH rat models. These preclinical findings add evidence supporting molecular…
Read ArticleIn guinea pigs, a HILIC-UHPLC-Q-TOF-MS-based protocol for untargeted metabolomics of perilymph is presented and shown to be fit-for-purpose. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential…
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