A preliminary therapeutic study of the effects of molecular hydrogen on intestinal dysbiosis and small intestinal injury in high-fat diet-loaded senescence-accelerated mice.
This animal study examined A preliminary therapeutic study of the effects of molecular hydrogen on intestinal dysbiosis and small intestinal injury in high-fat diet-loaded senescence-accelerated mice. The abstract describes Mouse model; sample size 10. The abstract reports: Our findings suggest that treatment with molecular hydrogen may affect microbiota profiling and suppress intestinal injury in HFD-loaded SAMP8. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-Rich Water Mitigates LPS-Induced Chronic Intestinal Inflammatory Response in Rats via Nrf-2 and NF-κB Signaling Pathways.
This animal study examined Hydrogen-Rich Water Mitigates LPS-Induced Chronic Intestinal Inflammatory Response in Rats via Nrf-2 and NF-κB Signaling Pathways. The abstract describes Rat model; hydrogen delivered as hydrogen water and injected or infused hydrogen. The abstract reports: The obtained results show that hydrogen-rich water significantly increased the levels of superoxide dismutase and structural proteins; activated the Nrf-2 signaling pathway; downregulated the…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen is comparable to sulfasalazine as a treatment for DSS-induced colitis in mice.
This animal study examined Molecular hydrogen is comparable to sulfasalazine as a treatment for DSS-induced colitis in mice. The abstract describes Mouse model; sample size 6; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreSirtuin Type 1 Mediates the Retinal Protective Effect of Hydrogen-Rich Saline Against Light-Induced Damage in Rats.
This animal study examined Sirtuin Type 1 Mediates the Retinal Protective Effect of Hydrogen-Rich Saline Against Light-Induced Damage in Rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen; reported duration 5 days. The abstract reports: Sirt1 mediates light-induced damage mitigation by HRS through inhibition of apoptosis and oxidant-stress. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe effect of Hydrogen-rich water on retinal degeneration in the outer nuclear layer of simulated weightlessness rats.
This animal study examined The effect of Hydrogen-rich water on retinal degeneration in the outer nuclear layer of simulated weightlessness rats. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: Oxidative stress has been identified as one of the contributing mechanisms of spaceflight-associated neuro-ocular syndrome (SANS), and hydrogen (H) has demonstrated significant antioxidant and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen postconditioning promotes survival of rat retinal ganglion cells against ischemia/reperfusion injury through the PI3K/Akt pathway.
This animal study examined Hydrogen postconditioning promotes survival of rat retinal ganglion cells against ischemia/reperfusion injury through the PI3K/Akt pathway. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: The results showed that administration of HPC significantly inhibited the apoptosis of RGCs and protected the visual function. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreDrinking hydrogen water improves photoreceptor structure and function in retinal degeneration 6 mice.
This animal study examined Drinking hydrogen water improves photoreceptor structure and function in retinal degeneration 6 mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: Given the known contributions of oxidative stress caused by reactive oxygen species (ROS) and selective inhibition of potent ROS peroxynitrite and OH·by H gas…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreSirt3 mediates the protective effect of hydrogen in inhibiting ROS-induced retinal senescence.
This animal study examined Sirt3 mediates the protective effect of hydrogen in inhibiting ROS-induced retinal senescence. The abstract describes Mouse model. The abstract reports: Moreover, this result was consistent with the downregulation of expression of the oxidative stress hallmark OGG1. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effects of hydrogen gas in a rat model of branch retinal vein occlusion via decreasing VEGF-α expression
This animal study examined Protective effects of hydrogen gas in a rat model of branch retinal vein occlusion via decreasing VEGF-α expression. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: Our findings demonstrate that inhalation of hydrogen gas could alleviate retinal oedema, shorten reopen time and improve retinal function, and the potential mechanism might…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline protects retina against glutamate-induced excitotoxic injury in guinea pig.
This in vitro or cellular study examined Hydrogen-rich saline protects retina against glutamate-induced excitotoxic injury in guinea pig. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: This result likely occurs by inhibiting the activation of glial cells, decreasing the production of the iNOS and GRP78 and promoting glutamate clearance. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effect of molecular hydrogen against oxidative stress caused by peroxynitrite derived from nitric oxide in rat retina.
This animal study examined Protective effect of molecular hydrogen against oxidative stress caused by peroxynitrite derived from nitric oxide in rat retina. The abstract describes Rat model. The abstract reports: H2 reduces cellular peroxynitrite, a highly toxic reactive nitrogen species. Thus, H2 may be an effective and novel clinical tool for treating glaucoma and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtection of the retina by rapid diffusion of hydrogen: administration of hydrogen-loaded eye drops in retinal ischemia-reperfusion injury.
This animal study examined Protection of the retina by rapid diffusion of hydrogen: administration of hydrogen-loaded eye drops in retinal ischemia-reperfusion injury. The abstract describes Rat model; reported duration 60 minutes. The abstract reports: H(2) has no known toxic effects on the human body. Thus, the results suggest that H(2)-loaded eye drops are a highly useful neuroprotective and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe Comparative Efficiency of Intraperitoneal and Intravitreous Injection of Hydrogen Rich Saline against -Methyl–Nitrosourea Induced Retinal Degeneration: A Topographic Study.
This animal study examined The Comparative Efficiency of Intraperitoneal and Intravitreous Injection of Hydrogen Rich Saline against -Methyl–Nitrosourea Induced Retinal Degeneration: A Topographic Study. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Particularly, the topographic measurements suggested that the IV delivery of HRS could alleviate MNU induced photoreceptor degeneration in the posterior retina. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of Post-Treatment Hydrogen Gas Inhalation on Uveitis Induced by Endotoxin in Rats.
This animal study examined Effects of Post-Treatment Hydrogen Gas Inhalation on Uveitis Induced by Endotoxin in Rats. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation and oxyhydrogen. The abstract reports: RESULTS No statistically significant differences existed in the graded score of uveitis and the b-wave peak time in the Dark-adapted 3.0 ERG among the…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effect of saturated hydrogen saline against blue light-induced retinal damage in rats.
This animal study examined Protective effect of saturated hydrogen saline against blue light-induced retinal damage in rats. The abstract describes Rat model; sample size 30; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen; reported duration 6 hours. The abstract reports: Saturated hydrogen saline could protect the retina from light-induced damage by attenuating oxidative stress. This is an automated editorial draft based on the abstract and requires source review before publication.
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