Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In rats, the mRNA and protein expressions of AQP1 in cerebral cortex were significantly decreased after hydrogen-rich water treatment [24-hour AQP1 mRNA (2-△△Ct):5.40±0.21 vs.7.50±0.26, 24-hour AQP1 protein (gray value): 1.246±0.137 vs.1.986±0.110, both P < 0.05]. These preclinical findings add evidence supporting molecular…
Read ArticleIn rats, compared with the model group, the inflammatory response of pregnancy gingivitis in HW group was significantly suppressed along with decreased NFκB and TNF-α. These preclinical findings…
Read ArticleIn Sprague Dawley rats, compared with those in burn group, the protein expressions of HMGB1 of rats in hydrogen-rich saline group at PIH 6, 24, and 72 were…
Read ArticleIn rats, nSS scores in TBI and TBI+HW groups showed a decreased tendency with time prolongation after TBI. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential…
Read ArticleIn rats, hydrogen inhalation decreased the expression of p-p38 MAPK in the lung tissue, and significantly reduced TNF-α content in the lung tissue and serum of rats with…
Read ArticleIn rats, resuscitation with HS could protect liver of severely scalded rats with delayed resuscitation possibly by reducing infiltration of neutrophils, thus lowering the content of inflammatory cytokines,…
Read ArticleIn female Wistar rats, hRS eyedrops group and HRS intraperitoneal injection group can relieve the signs of dry eye, improve the pathological damage of cornea and conjunctiva, and…
Read ArticleIn rats, hydrogen rich water can up-regulate the expression of Nrf2, and reduce oxidative damage of traumatic brain injury in rats. These preclinical findings add evidence supporting molecular…
Read ArticleIn male Sprague Dawley rats, hydrogen-rich saline can attenuate global cerebral I/R injure through inhibiting JNK, reducing the expression of FOXO3a. These preclinical findings add evidence supporting molecular…
Read ArticleIn male Sprague-Dawley rats, hydrogen-rich saline can reduce myocardial reperfusion injury and improve heart function. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes…
Read ArticleIn male Sprague-Dawley rats, hydrogen-rich saline may decrease cellular apoptosis and attenuate myocardial reperfusion injury through inhibiting endoplasmic reticulum stress. These preclinical findings add evidence supporting molecular hydrogen's…
Read ArticleIn mice, compared with sepsis group, neurological function significantly improved and damaged neurons in hippocampal CA1 region significantly reduced. The activities of SOD and CAT markedly increased and…
Read ArticleIn mice, hE staining showed that there was significantly aggravated intestinal pathological injury in the mice of sepsis group; compared with sepsis group, the pathology was significantly less…
Read ArticleIn mice, the 7-day survival rate of severe sepsis mice was 0; the 7-day survival rate was increased to 60% in hydrogen treatment group, with statistical significance in…
Read ArticleIn male C57BL/6 mice, the survival rate of animals increased significantly after propofol or hydrogen-rich treatment, and the combined treatment can further increase survival rate to 90%, 75%,…
Read Article