Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In male Sprague-Dawley rats, saturated hydrogen saline prevents the degradation of elastin in vessel wall and ameliorates the formation and development of AAA, which may be associated with its anti-inflammatory effects, thereby reduces the MMP-2 and 9 mRNA and protein expression. These…
Read ArticleIn rats, the cytotoxicity, the levels of ONOO(-) and 8-OHdG, and PAR expression in HG+H₂ group were significantly lower than those of the HG group (all P <…
Read ArticleIn mice, evidence is growing that hydrogen-rich saline may be an effective drug for the prevention and treatment of ALI. These preclinical findings add evidence supporting molecular hydrogen's…
Read ArticleThe researchers found that ARW-fed mice significantly ameliorated adiposity: controlled body weight gain, reduced the accumulation of epididymal fats and decreased liver fats as compared to control mice.…
Read ArticleIn male Sprague-Dawley rats,, the researchers found that Pec or HAS, which enhance H₂ generation in the large intestine, alleviated hepatic IR injury. These preclinical findings add evidence…
Read ArticleIn an animal model, kRAS, YWHAE, SP1 and MSRA might be regarded as focused biomarkers to assess the prognosis of EC. These preclinical findings add evidence supporting molecular…
Read ArticleIn mice, the daily administration of HRW also progressively reduced the thermal allodynia induced by PTX injection ( p < 0.001; one-way ANOVA, against vehicle plus vehicle-treated animals;…
Read ArticleIn rats, by scavenging ROS and inflammation via active hydrogen, the oxidative stress is relieved and the levels of inflammation cytokines are reduced by the authors' micromotors, showing…
Read ArticleIn mice, filtered water treatment suppressed proinflammatory cytokines and decreased the mRNA expression of TNF-α, IL-6, IL-1β, and NF-κB P65. These preclinical findings add evidence supporting molecular hydrogen's…
Read ArticleIn contrast, H₂ treatment markedly increased NF-κB activity and the expression of Bcl-xL and decreased the level of cleaved caspase-3. These preclinical findings add evidence supporting molecular hydrogen's…
Read ArticleIn an animal model, here, the researchers found that HS treatment significantly reduced infarct volume and improved neurobehavioral outcomes at 24h, 48h and 72h after pMCAO operation in…
Read ArticleIn an animal model, ninety-six hours survival rates were significantly higher in the H₂ (80.0%) and H₂+TH (90.0%) groups than TH (30.0%) and to Ctrl (30.0%). These preclinical…
Read ArticleIn Sprague-Dawley rats, intragastric administration of lactulose substantially increased breath hydrogen concentration. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways…
Read ArticleIn an animal model, ninety-six hours survival rate was significantly higher in the H₂ inhalation group (75.0%), either compared with TH (45.8%) or compared with Control (33.3%). These…
Read ArticleIn male C57BL/6 mice, intriguingly, hydrogen alleviated the endoplasmic reticulum stress via the autophagy pathway and also mitigated inflammation and organ injury. These preclinical findings add evidence supporting…
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