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Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In an animal model, hS significantly increased hydrogen concentration in liver and kidney tissues. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in this model.
Read ArticleIn an animal model, however, ALT and AST activity significantly decreased at T3h and T1d and AKP activity significantly decreased at T1d in the IRI + hydrogen-rich saline…
Read ArticleIn C57BL/6 mice, hCH significantly improved liver function, reduced serum inflammatory cytokines, and inhibited hepatocyte apoptosis, and also induced the PI3K-Akt pathway activation. These preclinical findings add evidence…
Read ArticleIn rats, hydrogen gas reduced hepatic reperfusion injury after prolonged cold preservation via the maintenance of portal flow, by protecting mitochondrial function during the early phase of reperfusion,…
Read ArticleIn C57BL/6 mice, culturing in the hydrogen-rich medium selectively suppressed the generation of hydroxyl radicals in hepatocytes and significantly suppressed hepatocyte death induced by antimycin A; however, it…
Read ArticleIn rats, hS appeared to significantly attenuate hepatic I/R-induced ER stress responses, as indicated by the decreased expression of C/EBP homologous protein, protein-kinase-RNA-like ER kinase, and inositol-requiring protein-1α,…
Read ArticleThe researchers found that saturated hydrogen saline treatment efficiently decreased the activation of ERK and JNK, while promoting the activation of p38 (P<0.05 compared with LPS), suggesting the…
Read ArticleThe results demonstrated that 2% H₂ gas inhalation resulted in an increase in the 7-day survival rate, ALT and AST levels, RCR, and P62 and LC3B-II expression but…
Read ArticleIn rats, no significant differences in dissolved H₂ or ORP values were observed in the HRW samples either at 4 °C or at 25 °C within 24 h.…
Read ArticleIn an animal model, mechanistically, the researchers discovered that sustained and ultrahigh H₂ supply by hydrogen nanocapsule increased, among other species, the abundance of Akkermansia muciniphila, highlighting reshaped…
Read ArticleIn rats, gene Ontology analysis revealed that genes for oxidoreduction-related proteins, including hydroxymethylglutaryl CoA reductase, were significantly enriched in the upregulated genes. These preclinical findings add evidence supporting…
Read ArticleIn mice, compared to RW and L-HRW, H-HRW resulted in a lower increase in fat mass (46% vs 61%), an increase in lean body mass (42% vs 28%),…
Read ArticleIn rats, the mechanism of this phenomenon suggests that H₂ may have effectively attenuated AOC‑induced inflammatory and oxidative damage, and decreased matrix metalloproteinase activity. These preclinical findings add…
Read ArticleIn rats, the hydrogen-rich UW solution group also showed less oxidative damage and hepatocyte apoptosis than the control group, and the expression of proinflammatory cytokines tended to be…
Read ArticleIn mice, cCl(4) also significantly decreased the activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px). These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the…
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