Hydrogen-supplemented drinking water protects cardiac allografts from inflammation-associated deterioration.

This in vitro or cellular study examined Hydrogen-supplemented drinking water protects cardiac allografts from inflammation-associated deterioration. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen water. The abstract reports: Recent evidence suggests that molecular hydrogen has therapeutic value for disease states that involve inflammation. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effect of hydrogen-rich saline on pressure overload-induced cardiac hypertrophyin rats: possible role of JAK-STAT signaling.

This animal study examined Protective effect of hydrogen-rich saline on pressure overload-induced cardiac hypertrophyin rats: possible role of JAK-STAT signaling. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Our results showed a protective effect of HRS on pressure overload-induced cardiac hypertrophy in rats, which may be associated to a decreasing in JAK-STAT…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen stabilizes atherosclerotic plaque in low-density lipoprotein receptor-knockout mice.

This animal study examined Molecular hydrogen stabilizes atherosclerotic plaque in low-density lipoprotein receptor-knockout mice. The abstract describes Mouse model. This is an automated editorial draft based on the abstract and requires source review before publication.

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Consumption of hydrogen water prevents atherosclerosis in apolipoprotein E knockout mice.

This in vitro or cellular study examined Consumption of hydrogen water prevents atherosclerosis in apolipoprotein E knockout mice. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen water. The abstract reports: We have found that hydrogen (dihydrogen; H(2)) acts as an effective antioxidant to reduce oxidative stress [I. This is an automated editorial draft based on the abstract and requires source review before publication.

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Administration of hydrogen-rich water prevents vascular aging of the aorta in LDL receptor-deficient mice.

This in vitro or cellular study examined Administration of hydrogen-rich water prevents vascular aging of the aorta in LDL receptor-deficient mice. The abstract describes Endothelial cell model; hydrogen delivered as hydrogen water; reported duration 13 weeks. The abstract reports: Recent studies showed that senescent cells are involved in the development and progression of atherosclerosis, and eliminating senescent cells suppresses the senescence-associated secretory phenotype. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen alleviates myocardial infarction by impeding apoptosis via ROS-mediated mitochondrial endogenous pathway

This animal study examined Hydrogen alleviates myocardial infarction by impeding apoptosis via ROS-mediated mitochondrial endogenous pathway. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: Overall, hydrogen inhalation reduces myocardial infarct size, improves mitochondrial dysfunction, and modulates the levels of apoptosis-related substances. Importantly, Hydrogen reduces acute myocardial infarction damage…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen promotes retinal vascular regeneration and attenuates neovascularization and neuroglial dysfunction in oxygen-induced retinopathy mice.

This animal study examined Molecular hydrogen promotes retinal vascular regeneration and attenuates neovascularization and neuroglial dysfunction in oxygen-induced retinopathy mice. The abstract describes Mouse model; reported duration 5 days. The abstract reports: Collectively, our results indicate that H could be a promising therapeutic agent for POR treatment and that its beneficial effect in human ROP might…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effects of hydrogen rich saline solution in rats with experimental myocardial ischemia reperfusion injury.

This animal study examined Protective effects of hydrogen rich saline solution in rats with experimental myocardial ischemia reperfusion injury. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Our study shows that HRSS is protective in IR injury, with the application of HRSS 5 min before reperfusion, interstitial edema severity, subendocardial haemorrhage are…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen potentiates beneficial anti-infarct effect of hypoxic postconditioning in isolated rat hearts: a novel cardioprotective intervention

This animal study examined Molecular hydrogen potentiates beneficial anti-infarct effect of hypoxic postconditioning in isolated rat hearts: a novel cardioprotective intervention. The abstract describes Rat model. This is an automated editorial draft based on the abstract and requires source review before publication.

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Chronic hydrogen-rich saline treatment attenuates vascular dysfunction in spontaneous hypertensive rats.

This uncontrolled human study examined Chronic hydrogen-rich saline treatment attenuates vascular dysfunction in spontaneous hypertensive rats. The abstract describes Human participants; hydrogen delivered as hydrogen-rich saline; reported duration 3 months. The abstract reports: Recently, it has been suggested that hydrogen exerts a therapeutic antioxidant activity by selectively reducing hydroxyl radical and peroxynitrite, the most cytotoxic chemicals of…. This is an automated editorial draft based on the abstract and requires source review before publication.

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1.2% Hydrogen gas inhalation protects the endothelial glycocalyx during hemorrhagic shock: a prospective laboratory study in rats

This animal study examined 1.2% Hydrogen gas inhalation protects the endothelial glycocalyx during hemorrhagic shock: a prospective laboratory study in rats. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: Inhalation of 1.2% H gas protected the endothelial glycocalyx and prolonged survival time during hemorrhagic shock. Therapeutic efficacy might vary depending on the concentration. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen (H) Inhibits Isoproterenol-Induced Cardiac Hypertrophy via Antioxidative Pathways.

This animal study examined Hydrogen (H) Inhibits Isoproterenol-Induced Cardiac Hypertrophy via Antioxidative Pathways. The abstract describes Mouse model; reported duration 7 days. This is an automated editorial draft based on the abstract and requires source review before publication.

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[Anti-injury effect of hydrogen-enriched water in a rat model of liver injury induced by aflatoxin B].

This animal study examined [Anti-injury effect of hydrogen-enriched water in a rat model of liver injury induced by aflatoxin B]. The abstract describes Rat model. The abstract reports: The results showed that, compared with the AFB group, the AFB+H group exhibited increased body weights, alleviated acute liver injury, decreased activities of serum…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Magnesium galvanic cells produce hydrogen and modulate the tumor microenvironment to inhibit cancer growth.

Hydrogen can be used as an anti-cancer treatment. However, the continuous generation of H molecules within the tumor is challenging. Magnesium (Mg) and its alloys have been extensively used in the clinic as implantable metals.

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Injectable anaerobic hydrogel loading Clostridium butyricum for local hydrogen therapy against colorectal cancer.

This animal study examined Injectable anaerobic hydrogel loading Clostridium butyricum for local hydrogen therapy against colorectal cancer. The abstract describes Animal model; hydrogen delivered as injected or infused hydrogen. The abstract reports: As a result, the encapsulated bacteria can produce H and metabolites throughout tumor regions-including both hypoxic zones and well-vascularized areas. This is an automated editorial draft based on the abstract and requires source review before publication.

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