Hydrogen gas inhalation during ex vivo lung perfusion of donor lungs recovered after cardiac death.
This animal study examined Hydrogen gas inhalation during ex vivo lung perfusion of donor lungs recovered after cardiac death. The abstract describes Animal model; hydrogen delivered as hydrogen inhalation; reported duration 1 hour. The abstract reports: Hydrogen gas inhalation during EVLP improved donation after cardiac death lung function via reduction of inflammation and apoptosis, and this effect persisted after LTx. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreCombination of Hydrogen Inhalation and Hypothermic Temperature Control After Out-of-Hospital Cardiac Arrest: A Post hoc Analysis of the Efficacy of Inhaled Hydrogen on Neurologic Outcome Following Brain Ischemia During PostCardiac Arrest Care II Trial.
This randomized controlled trial examined Combination of Hydrogen Inhalation and Hypothermic Temperature Control After Out-of-Hospital Cardiac Arrest: A Post hoc Analysis of the Efficacy of Inhaled Hydrogen on Neurologic Outcome Following Brain Ischemia During PostCardiac Arrest Care II Trial. The abstract describes Human participants; sample size 39; hydrogen delivered as hydrogen inhalation. The abstract reports: The Efficacy of Inhaled Hydrogen on Neurologic Outcome Following Brain Ischemia During Post-Cardiac Arrest Care (HYBRID) II trial (jRCTs031180352) suggested that hydrogen inhalation may…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline attenuates hippocampus endoplasmic reticulum stress after cardiac arrest in rats
This animal study examined Hydrogen-rich saline attenuates hippocampus endoplasmic reticulum stress after cardiac arrest in rats. The abstract describes Rat model; sample size 30; hydrogen delivered as hydrogen-rich saline. The abstract reports: Hydrogen-rich saline attenuates brain I/R injury may through inhibiting hippocampus ERS after cardiac arrest in rats. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInfluence of oxygen concentration on the neuroprotective effect of hydrogen inhalation in a rat model of cardiac arrest
This uncontrolled human study examined Influence of oxygen concentration on the neuroprotective effect of hydrogen inhalation in a rat model of cardiac arrest. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: In this CA rat model, inhaling 2% hydrogen combined with a high concentration of oxygen improved 96-h survival, either under normothermia or under hypothermia. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline improves survival and neurological outcome after cardiac arrest and cardiopulmonary resuscitation in rats.
This uncontrolled human study examined Hydrogen-rich saline improves survival and neurological outcome after cardiac arrest and cardiopulmonary resuscitation in rats. The abstract describes Human participants; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Hydrogen-rich saline treatment improved survival and neurological outcome after cardiac arrest/resuscitation in rats, which was partially mediated by reducing oxidative stress, inflammation, and apoptosis. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEfficacy of inhaled HYdrogen on neurological outcome following BRain Ischemia During post-cardiac arrest care (HYBRID II trial): study protocol for a randomized controlled trial.
This study protocol examined Efficacy of inhaled HYdrogen on neurological outcome following BRain Ischemia During post-cardiac arrest care (HYBRID II trial): study protocol for a randomized controlled trial. The abstract describes Planned or registered research population; hydrogen delivered as hydrogen inhalation. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe neuroprotective effects of intraperitoneal injection of hydrogen in rabbits with cardiac arrest.
This animal study examined The neuroprotective effects of intraperitoneal injection of hydrogen in rabbits with cardiac arrest. The abstract describes Rabbit model; hydrogen delivered as injected or infused hydrogen. The abstract reports: Intraperitoneal injection of H2 is a novel hydrogen administration method and can reduce cerebral ischemia-reperfusion injury and improve the prognosis of cardiopulmonary cerebral resuscitation…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas with extracorporeal cardiopulmonary resuscitation improves survival after prolonged cardiac arrest in rats.
This uncontrolled human study examined Hydrogen gas with extracorporeal cardiopulmonary resuscitation improves survival after prolonged cardiac arrest in rats. The abstract describes Human participants. The abstract reports: H therapy improved mortality in highly lethal CA rats rescued by ECPR and helped recover brain electrical activity. The underlying mechanism might be linked…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Inhalation During Normoxic Resuscitation Improves Neurological Outcome in a Rat Model of Cardiac Arrest Independently of Targeted Temperature Management
This animal study examined Hydrogen Inhalation During Normoxic Resuscitation Improves Neurological Outcome in a Rat Model of Cardiac Arrest Independently of Targeted Temperature Management. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: H2 inhalation was beneficial when begun after ROSC, even when delivered in the absence of hyperoxia. Combined TTM and H2 inhalation was more effective…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreAssociation between hydrogen gas inhalation and cardiac output in an asphyxiated piglet model
This animal study examined Association between hydrogen gas inhalation and cardiac output in an asphyxiated piglet model. The abstract describes Porcine model; hydrogen delivered as hydrogen inhalation. The abstract reports: The HI group (n = 10) showed a transient increase in SV and CO followed by a decline. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtection of the endothelium and endothelial glycocalyx by hydrogen against ischaemia-reperfusion injury in a porcine model of cardiac arrest.
This animal study examined Protection of the endothelium and endothelial glycocalyx by hydrogen against ischaemia-reperfusion injury in a porcine model of cardiac arrest. The abstract describes Porcine model; hydrogen delivered as hydrogen inhalation. The abstract reports: In pigs, hydrogen gas inhalation during CPR and post-resuscitation care was associated with less pronounced metabolic acidosis compared to controls. However, we could not…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhalation of high concentration hydrogen gas improves short-term outcomes in a rat model of asphyxia induced-cardiac arrest
This animal study examined Inhalation of high concentration hydrogen gas improves short-term outcomes in a rat model of asphyxia induced-cardiac arrest. The abstract describes Rat model; reported duration 1 hour. The abstract reports: Findings of this preclinical study suggest that water electrolysis-derived 60% hydrogen gas may improve short-term outcomes in cardiogenic global brain hypoxia-ischemia. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreFeasibility and Safety of Hydrogen Gas Inhalation for Post-Cardiac Arrest Syndrome - First-in-Human Pilot Study.
This uncontrolled human study examined Feasibility and Safety of Hydrogen Gas Inhalation for Post-Cardiac Arrest Syndrome - First-in-Human Pilot Study. The abstract describes Human participants; sample size 107; hydrogen delivered as hydrogen inhalation. The abstract reports: HI in combination with TTM is a feasible therapy for patients with PCAS. (Circ J 2016; 80: 1870-1873). This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEvaluation of the effect of enriched hydrogen saline solution on distant organ (lung) damage in skeletal muscle ischemia reperfusion in rats.
This animal study examined Evaluation of the effect of enriched hydrogen saline solution on distant organ (lung) damage in skeletal muscle ischemia reperfusion in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: HRS at a dose of 20 mg/kg, administered intraperitoneally 30 min before ischemia in rats, reduced lipid peroxidation and oxidative stress, while also reducing IR damage…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreA case of lung injury due to a hydrogen explosion caused by the simultaneous use of two home folk remedies devices.
This uncontrolled human study examined A case of lung injury due to a hydrogen explosion caused by the simultaneous use of two home folk remedies devices. The abstract describes Human participants. The abstract reports: Arterial blood gas analysis showed no deterioration, and computed tomography revealed no worsening of pulmonary findings or oxygen demand. This is an automated editorial draft based on the abstract and requires source review before publication.
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