Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
This narrative review examined the available molecular-hydrogen literature. Hydrogen is primarily administered via inhalation, drinking hydrogen-rich water, or injection of hydrogen-rich water. The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.
Read ArticleIn an animal model, inhalation of hydrogen gas protects against myocardial stunning and infarction in swine. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the…
Read ArticleIn rats, using this system, the concentration of H₂ in unit volume can be greatly improved under normal temperature and pressure conditions. These preclinical findings add evidence supporting…
Read ArticleIn male Wistar rats, the apoptosis rate was significantly decreased in the hydrogen-rich water group, as well. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within…
Read ArticleIn rats, nFkB-p65 and c-Fos in the nucleus were unexpectedly unchanged by IRI regardless of H₂ treatment, indicating the absence of inflammation in this model. These preclinical findings…
Read ArticleIn rats, hydrogen-containing saline (HCS) treatment was observed to improve interstitial fibrosis and cardiac function and to decrease the level of ROS, the oxidative‐stress marker MDA and expression…
Read ArticleIn mice, although treatment of diabetic mice with hydrogen water did not significantly affect blood glucose level, it significantly attenuated cardiac hypertrophy and reduced expression of atrial natriuretic…
Read ArticleIn rats, it also decreased neutrophil infiltration, 3-nitrotyrosine level, expression of intercellular adhesion molecule 1(ICAM-1) and myeloperoxidase (MPO) activity in the area at risk zones (AAR) of rat…
Read ArticleIn a laboratory model, when the cells were exposed to SGD, levels of intracellular ·OH free radicals were markedly increased; this was mitigated by H₂ gas‐rich medium. The…
Read ArticleIn rats, finally, as a pivotal transcription factor in reactive oxygen species (ROS)-apoptosis signaling pathway, the expression and phosphorylation of p53 were significantly reduced by H₂ treatment in…
Read ArticleIn mice, nO inhalation plus H₂ reduced the infarct size/AAR, with significant interaction between the two, reducing ROS and neutrophil infiltration, and improved the cardiac function to normal…
Read ArticleIn a laboratory model, the OC in the hydrogen group was higher than in the control group, but the difference was not statistically significant (P = 0.0862). The…
Read ArticleIn Sprague Dawley rats, hRS treatment significantly increased the viability of myocardial cells, reduced the rate of myocardial cellular apoptosis and the release of MDA and LDH compared…
Read ArticleThis animal study examined Hydrogen-rich saline protects myocardium against ischemia/reperfusion injury in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen.…
Read ArticleT cell proliferation was significantly inhibited in the presence of hydrogen in vitro, accompanied by less production of interleukin-2 and interferon-γ, hydrogen treatment was also associated with increased…
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