Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
Ohta's group indicated that cells cultured in H₂-rich medium were protected against oxidative stress by the hydroxyl radical-scavenging activity of H₂; however, recent evidence clearly shows that the scavenging property is not the only explanation for the potent beneficial effects of hydrogen.…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.
Read ArticleThis narrative review examined the available molecular-hydrogen literature. The search strategy included combinations of keywords such as “chronic kidney disease,” “oxidative stress,” “inflammation,” “antioxidant therapy,” “molecular hydrogen,” “H₂…
Read ArticleThe results demonstrate that H(2) treatment is beneficial to ouabain-induced AN via reducing apoptosis. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and…
Read ArticleIn an animal model, the mechanism by which hydrogen gas alleviates TBI may be related to inhibiting NLRP3 inflammasomes in the cerebral cortex of rats. These preclinical findings…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. H₂ has been reported to mitigate the side effects of anticancer drugs in animal studies and clinical trials, the authors'…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Accumulating evidence suggest that H₂ is protective against multiple ophthalmic diseases, including cataracts, dry eye disease, diabetic retinopathy (DR) and…
Read ArticleIn rats, compared with CIH group, the pathology of liver microstructure were significantly improved and the serum levels of ALT, AST were significantly lower in H₂+CIH group (P<0.05);…
Read ArticleIn 100 healthy participants with no sleep disorders, no significant difference in the percent change of HRV paraments (i.e., LF/HF, RMSSD, SDNN, LF average, HF average, VLF average)…
Read ArticleIn mice, exogenous H₂ reprograms colonocyte metabolism by regulating the H₂-gut microbiota-SCFAs axis and strengthens the intestinal barrier by modulating specific mucosa-associated mucolytic bacteria, wherein improved microbial hydrogen…
Read ArticleIn mice, it was also found that compared with the HRS group, overexpression of calpain1 increased caspase-3 activities, promoted cleaved-caspase3 and Bax protein expressions, and correspondingly decreased Bcl-2,…
Read ArticleIn participants, molecular hydrogen (H₂) has the potential to be a radioprotective agent because it can selectively scavenge •OH, a reactive oxygen species with strong oxidizing power. These…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. In recent years, several studies have provided preliminary evidence for the protective effects of hydrogen on spinal cord injury (SCI).…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Recently, it has been reported that molecular hydrogen (H₂) functions as an antioxidant and anti-inflammatory agent. The reviewed evidence adds…
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