A narrative review of hydrogen therapy for COPD: aging-related insights.

This narrative review examined A narrative review of hydrogen therapy for COPD: aging-related insights. The abstract describes Published literature review. The abstract reports: H therapy shows consistent antioxidative, anti-inflammatory, and anti-senescence effects across preclinical and clinical settings, suggesting potential as an adjunctive treatment for COPD in aging…. This is an automated editorial draft based on the abstract and requires source review before publication.

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High Concentration Hydrogen Mitigates Sepsis-Induced Acute Lung Injury in Mice by Alleviating Mitochondrial Fission and Dysfunction.

This animal study examined High Concentration Hydrogen Mitigates Sepsis-Induced Acute Lung Injury in Mice by Alleviating Mitochondrial Fission and Dysfunction. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: Lungs are among the organs that are affected in MOF, resulting in acute lung injury. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen inhalation attenuates lung contusion after blunt chest trauma in mice.

This animal study examined Hydrogen inhalation attenuates lung contusion after blunt chest trauma in mice. The abstract describes Mouse model; sample size 6; hydrogen delivered as hydrogen inhalation. The abstract reports: Hydrogen inhalation therapy significantly mitigated inflammatory responses associated with lung contusion in mice. Hydrogen inhalation therapy may be a supplemental therapeutic strategy for treating…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas alleviates lipopolysaccharide-induced acute lung injury and inflammatory response in mice.

This animal study examined Hydrogen gas alleviates lipopolysaccharide-induced acute lung injury and inflammatory response in mice. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: Hydrogen gas alleviates lipopolysaccharide-induced acute lung injury and inflammatory response most probably through the TLR4-NF-κB pathway. This is an automated editorial draft based on the abstract and requires source review before publication.

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The use of ultrapure molecular hydrogen enriched with atomic hydrogen in apparatuses of artificial lung ventilation in the fight against virus COVID-19.

This uncontrolled human study examined The use of ultrapure molecular hydrogen enriched with atomic hydrogen in apparatuses of artificial lung ventilation in the fight against virus COVID-19. The abstract describes Human participants; hydrogen delivered as oxyhydrogen. The abstract reports: Many studies have been carried out that have demonstrated that hydrogen has strong anti-inflammatory properties. This is an automated editorial draft based on the abstract and requires source review before publication.

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The effects of inhaling hydrogen gas on macrophage polarization, fibrosis, and lung function in mice with bleomycin-induced lung injury.

This animal study examined The effects of inhaling hydrogen gas on macrophage polarization, fibrosis, and lung function in mice with bleomycin-induced lung injury. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: The results suggest that hydrogen inhalation inhibits the deterioration of respiratory physiological function and alveolar fibrosis in this model of lung injury. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effects of molecular hydrogen on lung injury from lung transplantation

This narrative review examined Protective effects of molecular hydrogen on lung injury from lung transplantation. The abstract describes Published literature review; hydrogen delivered as hydrogen water and hydrogen-rich saline and injected or infused hydrogen. The abstract reports: The reviewed studies showed that H improved the outcomes of lung transplantation by decreasing oxidative stress and inflammation at the donor and recipient phases. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas (XEN) inhalation ameliorates airway inflammation in asthma and COPD patients.

This observational study examined Hydrogen gas (XEN) inhalation ameliorates airway inflammation in asthma and COPD patients. The abstract describes Human participants; sample size 10; hydrogen delivered as hydrogen inhalation; reported duration 45 min. The abstract reports: A single inhalation of hydrogen for 45 min attenuated inflammatory status in airways in patients with asthma and COPD. This is an automated editorial draft based on the abstract and requires source review before publication.

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Attenuation of pulmonary damage in aged lipopolysaccharide-induced inflammation mice through continuous 2 % hydrogen gas inhalation: A potential therapeutic strategy for geriatric inflammation and survival.

This animal study examined Attenuation of pulmonary damage in aged lipopolysaccharide-induced inflammation mice through continuous 2 % hydrogen gas inhalation: A potential therapeutic strategy for geriatric inflammation and survival. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation and hydrogen-rich saline and injected or infused hydrogen. The abstract reports: The study highlights that continuous inhalation of hydrogen gas at a 2 % concentration for 24 h can be a potent intervention in the geriatric population…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Itraq-Based Quantitative Proteomic Analysis of Lungs in Murine Polymicrobial Sepsis with Hydrogen Gas Treatment.

This uncontrolled human study examined Itraq-Based Quantitative Proteomic Analysis of Lungs in Murine Polymicrobial Sepsis with Hydrogen Gas Treatment. The abstract describes Human participants. The abstract reports: Functional enrichment analysis showed that H2-related differential proteins could be related to muscle contraction, oxygen transport, protein synthesis, collagen barrier membranes, cell adhesion, and…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen protects lung from hypoxia/re-oxygenation injury by reducing hydroxyl radical production and inhibiting inflammatory responses.

This animal study examined Hydrogen protects lung from hypoxia/re-oxygenation injury by reducing hydroxyl radical production and inhibiting inflammatory responses. The abstract describes Mouse model. The abstract reports: We found that H/R-induced injury in our mouse model was associated with production of hydroxyl radicals as well as increased levels of colony-stimulating factors…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effects of hydrogen-rich saline treatment on polymicrobial sepsis.

This animal study examined Effects of hydrogen-rich saline treatment on polymicrobial sepsis. The abstract describes Rat model; sample size 8; hydrogen delivered as hydrogen-rich saline. The abstract reports: HRS has potential protective effects against sepsis by decreasing proinflammatory responses, oxidative stress, and apoptosis in a rat model of polymicrobial sepsis. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline provides protection against hyperoxic lung injury.

This animal study examined Hydrogen-rich saline provides protection against hyperoxic lung injury. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: The results of this study demonstrate that hydrogen-rich saline ameliorated hyperoxia-induced acute lung injury by reducing oxidative stress and inflammatory cascades in lung tissue. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen ameliorates lipopolysaccharide-induced acute lung injury in mice through reducing inflammation and apoptosis.

This uncontrolled human study examined Molecular hydrogen ameliorates lipopolysaccharide-induced acute lung injury in mice through reducing inflammation and apoptosis. The abstract describes Human participants; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Recently, our and other studies have found that hydrogen gas (H₂) treatment can ameliorate the lung injury induced by sepsis, ventilator, hyperoxia, and ischemia-reperfusion. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline ameliorates lung injury associated with cecal ligation and puncture-induced sepsis in rats.

This animal study examined Hydrogen-rich saline ameliorates lung injury associated with cecal ligation and puncture-induced sepsis in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: This observation indicated that hydrogen-rich saline peritoneal injection improves histological and functional assessment in rat model of CLP-induced ALI. The therapeutic effects of hydrogen-rich…. This is an automated editorial draft based on the abstract and requires source review before publication.

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