Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In a laboratory model, specifically, post systemic transplantation, H₂ generators-laden MSCs home to OA joints, and upon stimulation in acidic OA environment, H₂ produced from the generators remodels articular redox balance, thereby relieving the loss of mitochondrial membrane potential, decreasing cellular apoptosis…
Read ArticleIn a laboratory model, beyond its role in providing physical support for vessel ingrowth, the researchers found that Mg/Gel secures its localized and sustained H₂ release due to…
Read ArticleIn rats, the contents of proinflammatory factors tumor necrosis factor alpha (TNF‐ α ), interleukin‐1 beta (IL‐1 β ), and interleukin‐6 (IL‐6) in PB serum and gingival crevicular…
Read ArticleIn male Sprague-Dawley rats, during partial CPB in rats, administration of 4% hydrogen via artificial and autologous lungs attenuated endothelial glycocalyx damage caused by CPB. These preclinical findings…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. During HD with an H₂-enriched solution (approximately 50 ppb H₂), markers of increased oxidative stress (such as interleukin-6, myeloperoxidase, methemoglobin,…
Read ArticleIn Of these antioxidants, the effects of alkaline reduced water (ARW) in oxidative stress of intestinal epithelial cells and its immunokine modulation in vitro is unknown, of these…
Read ArticleThe researchers found that a high concentration of H₂ (66% H₂ ) greatly increased the healing rate (3 times higher than the control group) on day 11 post…
Read ArticleIn participants, compared to baseline, the levels of lipoprotein(a) was decreased, the malondialdehyde content was reduced, the superoxide dismutase activity was increased, and the expression of intercellular cell…
Read ArticleIn this study, the researchers found that HRW treatment significantly improved CAT and SOD activities of the brain, liver, and gill origin exposed to microplastic damage. The authors…
Read ArticleIn 1 patients with laboratory-confirmed COVID-19 from seven hospitals in China demonstrated, a two-way mixed ANOVA (treatment vs. time interaction) revealed no significant differences for patient-reported outcomes (e.g.,…
Read ArticleIn In vitro, the generated hydrogen mitigates oxidative stress and inflammation, report a hybrid peptide–nanocluster hydrogel that establishes a self‐sustained anaerobic microenvironment, enabling hydrogenase‐catalyzed hydrogen therapy under aerobic…
Read ArticleThis narrative review examined the aim of this narrative review was to synthesize and critically evaluate current evidence on the physiological effects, recovery mechanisms, and performance outcomes associated…
Read ArticleIn B-cells are a keystone of the adaptive immune response and are essential for the presentation of tumor-associated antigens to various types of T-cells, analysis details a significant…
Read ArticleIn a laboratory model, demonstrate marked alleviation of psoriasis-like pathologies with this local hydrogen treatment in vitro and in vivo, revealing superior efficacy compared to both Imiquimod-induced mice…
Read ArticleIn a rat model of myocardial I/R injury, inhalation of 2% H₂ at the onset of ischemia, and for 60 min after reperfusion, reduced infarct size, lowered LV-end-diastolic…
Read Article