Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In vitro results showed that PDA@ZIF-8@AB nanoparticles can release H₂ continuously for up to 5 days in an acidic microenvironment, while the photothermal properties of PDA facilitated controlled release of QX-314 through 6 cycles of near-infrared (NIR) exposure. The authors concluded that…
Read ArticleIn Sprague-Dawley rats, hS treatment attenuated increases in apoptosis and autophagy postburn in wounds, according to the TUNEL staining results and the expression analysis of Bax, Bcl-2, caspase-3,…
Read ArticleIn male Sprague-Dawley rats, hydrogen-rich saline ameliorated inflammatory infiltration and decreased cellular apoptosis. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological…
Read ArticleIn rats, hRS treatment also reduced inflammatory cell infiltration induced by I/R injury. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological…
Read ArticleIn male Sprague Dawley rats, preconditioning with one-time inhaled hydrogen does not attenuate skin flap IR injuries in rat models. These preclinical findings add evidence about the molecular-hydrogen…
Read ArticleAt week 8, the authors' parallel-controlled trial revealed 24.4% of patients (10/41) receiving hydrogen-water bathing achieved at least 75% improvement in Psoriasis Area Severity Index (PASI) score compared…
Read ArticleIn rats, the mRNA expression of iNOS in rats with hydrogen-rich water intake was lower than that in the control group at both 3 and 7 days after…
Read ArticleIn mice, hydrogen water (HW) produced by electrolysis of water has characteristics of extremely low oxidation-reduction potential (ORP) value and high dissolved hydrogen (DH). These preclinical findings add…
Read ArticleIn mice, the levels of Th2 cytokine, interleukin-5 (IL-5), and proinflammatory cytokines such as tumor necrosis factor-α and IL-6 in HW-fed mice were significantly lower than in control…
Read ArticleIn mice, hydrogen water treatment decreased serum TARC levels from 73.3±27.9 pg/mL at baseline to 53.2±18.3 pg/mL at week 4 ( p =0.0107); however, no differences were detected…
Read ArticleIn 15 participants, the hypothesis was that H₂, through its selective antioxidant and anti-inflammatory properties, would reduce oxidative stress, modulate inflammatory pathways, and enhance skin barrier integrity, leading…
Read ArticleIn an animal model, consistently, hydrogen decreased proliferative marker expression, including BCL2, BAX, and Ki-67, and significantly reduced ROS and inflammatory cytokines production. These preclinical findings add evidence…
Read ArticleIn a study on a squamous cell carcinoma model in mice, Dole et al 68 conducted a high-pressure hydrogen treatment and found that mice with skin squamous cell…
Read ArticleIn mice, HRW significantly reduced plasma triglyceride and total cholesterol levels, increased high-density lipoprotein cholesterol levels, and alleviated skin lesions in mice. These preclinical findings add evidence supporting…
Read ArticleIn the iGTE, PMA/LPS significantly reduced the epithelial thickness while causing a decrease in K8/18, E-cadherin, laminin and elastin expression and an increase in COX-2 expression along with…
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