Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In the iGTE, PMA/LPS significantly reduced the epithelial thickness while causing a decrease in K8/18, E-cadherin, laminin and elastin expression and an increase in COX-2 expression along with ulcer-like lesions. These findings from a laboratory model add evidence supporting molecular hydrogen's biological…
Read ArticleIn mice, by naked eye, the severity of skin lesions in hydrogen-rich water bath group was lower than that in distilled water bath group, and the psoriasis severity…
Read ArticleIn mice, local treatment of hydrogen-rich water shortened wound closure time and reduced the level of proinflammatory cytokines and lipid peroxidation. These preclinical findings add evidence supporting molecular…
Read ArticleIn rats, the Si-based agent was found to effectively suppress I/R injury in skin flaps, and allow for the production of a large amount of hydrogen continuously via…
Read ArticleIn rats, prophylactic instillation of hydrogen suppressed alkali burn-induced oxidative stress of the cornea and promoted wound healing. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential…
Read ArticleIn dogs, HRW treatment promoted skin wound healing in dogs, accelerated wound epithelization, reduced inflammatory reaction, stimulated the expression of cytokines related to wound healing, and shortened wound…
Read ArticleIn Sprague-Dawley rats, repeated HRS injections after trauma increased the viability of skin flap in rat degloving injury model by decreasing local tissue injury, due to its antioxidant,…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. This review synthesises the current evidence on H₂ therapy in SAE and highlights key directions for future research, focusing on…
Read ArticleIn mice, hydrogen treatment upregulated SIRT1 expression and promoted PINK1/Parkin-mediated mitophagy, leading to reduced phosphorylation of STING, decreased levels of pro-inflammatory cytokines (IL-1β, IL-6, and TNF-α), and suppressed…
Read ArticleIn MHY1485, an mTOR activator, abolished the protective effects of hydrogen in vitro, hydrogen treatment decreased the ratio of p-mTOR/mTOR and the expression of p62 and increased the…
Read ArticleThe second hypothesis is that H₂ treatment decreases sepsis-induced neuroinflammation in the hippocampus and prefrontal cortex, important areas related to short and long-term memory processing. This source-grounded publication…
Read ArticleIn The cells were resuspended in DMEM supplemented with 10% (v/v) FBS, 1% (v/v) penicillin and streptomycin to adjust the cell density to 1.5×10 6 /ml, H₂ alleviated…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Meanwhile, combination therapy with H₂ (2%) and hyperoxia (98%) increases the 14-day survival rate of moderate sepsis mice to 100%…
Read ArticleIn mice, therapy with 2% H₂ increased the survival rate, alleviated the injuries caused by oxidative stress and inflammation, reduced HMGB1 levels but increased HO-1 levels in WT…
Read ArticleThis narrative review examined the findings of recent studies on the use of hydrogen in emergency and critical care medicine using different disease models. Hydrogen is a new…
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