Delivery of Molecular Hydrogen for Precision Immunomodulation: Mechanisms, Detection Methods, and Applications
This narrative review examined Delivery of Molecular Hydrogen for Precision Immunomodulation: Mechanisms, Detection Methods, and Applications. The abstract describes Published literature review. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe Effect of Adjuvant Therapy with Molecular Hydrogen on Endogenous Coenzyme Q Levels and Platelet Mitochondrial Bioenergetics in Patients with Non-Alcoholic Fatty Liver Disease.
This uncontrolled human study examined The Effect of Adjuvant Therapy with Molecular Hydrogen on Endogenous Coenzyme Q Levels and Platelet Mitochondrial Bioenergetics in Patients with Non-Alcoholic Fatty Liver Disease. The abstract describes Human participants; sample size 30; hydrogen delivered as hydrogen water; reported duration 8 weeks. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen inhalation ameliorates hepatic inflammation and modulates gut microbiota in rats with high-fat diet-induced non-alcoholic fatty liver disease.
This animal study examined Hydrogen inhalation ameliorates hepatic inflammation and modulates gut microbiota in rats with high-fat diet-induced non-alcoholic fatty liver disease. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation; reported duration 10 weeks. The abstract reports: Liver transcriptomic data suggested that H treatment significantly downregulated inflammatory response genes, and the lipopolysaccharide (LPS)/Toll-like receptor (TLR) 4/nuclear transcription factor kappa B (NF-κB)…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreCombination of Cold Storage in a Heavy Water-Containing Solution and Post-Reperfusion Hydrogen Gas Treatment Reduces Ischemia-Reperfusion Injury in Rat Livers
This animal study examined Combination of Cold Storage in a Heavy Water-Containing Solution and Post-Reperfusion Hydrogen Gas Treatment Reduces Ischemia-Reperfusion Injury in Rat Livers. The abstract describes Rat model. The abstract reports: Multiple comparison tests among the UW, Dsol, UW-H, and Dsol-H groups revealed that both treatments, during CS and after reperfusion, conferred a similar extent…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas alleviates acute alcohol-induced liver injury by inhibiting JNK activation.
This animal study examined Hydrogen gas alleviates acute alcohol-induced liver injury by inhibiting JNK activation. The abstract describes Mouse model; reported duration 4 days. The abstract reports: Therefore, the results of the present study demonstrated that treatment with exogenous H by intraperitoneal injection may alleviate acute alcohol-induced liver injury by inhibiting…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen treatment: a novel option in liver diseases.
This narrative review examined Hydrogen treatment: a novel option in liver diseases. The abstract describes Published literature review. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreConcomitant inhibition of oxidative stress and angiogenesis by chronic hydrogen‐rich saline and N‐acetylcysteine treatments improves systemic, splanchnic and hepatic hemodynamics of cirrhotic rats
This animal study examined Concomitant inhibition of oxidative stress and angiogenesis by chronic hydrogen‐rich saline and N‐acetylcysteine treatments improves systemic, splanchnic and hepatic hemodynamics of cirrhotic rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline; reported duration 1 month. The abstract reports: Both hydrogen-rich saline and N-acetylcysteine alleviate portal hypertension, the severity of portosystemic collaterals, mesenteric angiogenesis, hepatic endothelial dysfunction and intrahepatic resistance in cirrhotic rats.…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhalation of hydrogen gas suppresses hepatic injury caused by ischemia/reperfusion through reducing oxidative stress.
This animal study examined Inhalation of hydrogen gas suppresses hepatic injury caused by ischemia/reperfusion through reducing oxidative stress. The abstract describes Mouse model; reported duration 90 min. The abstract reports: We have recently showed that molecular hydrogen has great potential for selectively reducing cytotoxic reactive oxygen species, such as hydroxyl radicals, and that inhalation…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas inhalation protects against liver ischemia/reperfusion injury by activating the NF-κB signaling pathway.
This animal study examined Hydrogen gas inhalation protects against liver ischemia/reperfusion injury by activating the NF-κB signaling pathway. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation; reported duration 90 min. The abstract reports: Hydrogen has been demonstrated to function as a novel antioxidant and exert therapeutic antioxidant activity in a number of diseases. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline protects against hepatic injury induced by ischemia-reperfusion and laparoscopic hepatectomy in swine.
This animal study examined Hydrogen-rich saline protects against hepatic injury induced by ischemia-reperfusion and laparoscopic hepatectomy in swine. The abstract describes Porcine model; hydrogen delivered as hydrogen-rich saline. The abstract reports: HRS treatment may exert a protective effect against I/R and hepatectomy-induced hepatic damage by reducing oxidative stress, suppressing the inflammatory response and promoting liver…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHyperoxygenated hydrogen-rich solution suppresses shock- and resuscitation-induced liver injury.
This animal study examined Hyperoxygenated hydrogen-rich solution suppresses shock- and resuscitation-induced liver injury. The abstract describes Rat model; hydrogen delivered as injected or infused hydrogen. The abstract reports: HHOS has protective effects against liver injury in a rat model of HSR. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline protects against liver injury in rats with obstructive jaundice.
This animal study examined Hydrogen-rich saline protects against liver injury in rats with obstructive jaundice. The abstract describes Rat model; sample size 56; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Hydrogen-rich saline attenuates BDL-induced liver damage, possibly by the reduction of inflammation and oxidative stress and the inhibition of the ERK1/2 pathway. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHigh-content hydrogen water-induced downregulation of miR-136 alleviates non-alcoholic fatty liver disease by regulating Nrf2 via targeting MEG3.
This animal study examined High-content hydrogen water-induced downregulation of miR-136 alleviates non-alcoholic fatty liver disease by regulating Nrf2 via targeting MEG3. The abstract describes Mouse model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline protects against small-scale liver ischemia-reperfusion injury by inhibiting endoplasmic reticulum stress.
This animal study examined Hydrogen-rich saline protects against small-scale liver ischemia-reperfusion injury by inhibiting endoplasmic reticulum stress. The abstract describes Animal model; hydrogen delivered as hydrogen-rich saline. The abstract reports: We observed that HRS visibly improved ischemia-reperfusion injury (IRI) by reducing various parameters of ERS stress as evidenced by down-regulation of the mRNA as…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effects of hydrogen enriched saline on liver ischemia reperfusion injury by reducing oxidative stress and HMGB1 release.
This animal study examined Protective effects of hydrogen enriched saline on liver ischemia reperfusion injury by reducing oxidative stress and HMGB1 release. The abstract describes Rat model; hydrogen delivered as injected or infused hydrogen. The abstract reports: These results suggest that, in our model, hydrogen enriched saline treatment is protective against liver ischemia-reperfusion injury. This effect may be mediated by both…. This is an automated editorial draft based on the abstract and requires source review before publication.
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