Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In mice, the removal of mtROS by H₂ reduced the generation of oxidized mitochondrial DNA and consequently decreased its binding to NLRP3, thereby inhibiting the NLRP3 inflammasome activation. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and…
Read ArticleIn 0 patients with progressive muscular dystrophy (PMD), less prominent effects with the double-blind trial compared to the open-label trial were likely due to a lower amount of…
Read ArticleIn contrast, hydrogen gas may have increased survival of animals that would have died without treatment, thus biasing the neurobehavior scores of the SAH + hydrogen group toward…
Read ArticleIn rats, hydrogen gas reduced brain swelling, improved neurological function, and lowered markers of oxidative stress and neuronal pyroptosis after subarachnoid hemorrhage. These preclinical findings add evidence supporting…
Read ArticleIn mice, the infarct volume of mice in the HRS‑H group decreased significantly compared to that of the distal middle cerebral artery occlusion (dMCAO) group. These preclinical findings…
Read ArticleIn male Wistar rats, however, inhalation of H₂ gas after ROSC significantly decreased the number of abnormal mitochondria and increased the relative mitochondrial mass in rat LVs, and…
Read ArticleThese results show that molecular hydrogen given in drinking water reverses many of the sequelae of CCI and suggests that it could be an easily administered, highly effective…
Read ArticleThe researchers found that a high concentration of H₂ (66% H₂) greatly increased the healing rate (3 times higher than the control group) on day 11 post-wounding. The…
Read ArticleIn 22 patients with PU were recruited in the present study, eLEVATION OF CELL VIABILITY BY PRE-IRRADIATIONAL ADMINISTRATION WITH HYDROGEN-DISSOLVED WATER TO UVA-IRRADIATED HACAT CELLS AS ASSESSED BY…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. This review synthesises the current evidence on H₂ therapy in SAE and highlights key directions for future research, focusing on…
Read ArticleIn The cells were resuspended in DMEM supplemented with 10% (v/v) FBS, 1% (v/v) penicillin and streptomycin to adjust the cell density to 1.5×10 6 /ml, H₂ alleviated…
Read ArticleIn Animal models of SAE were generated by cecal ligation and puncture, and the SAE model was established by in vitro LPS stimulation, finally, hydrogen treatment improved the…
Read ArticleIn mice, inhalation of 67% H₂ improved the 7-day survival rates and recognition memory function of septic mice, alleviated brain antioxidant enzyme activity (SOD and CAT), and reduced…
Read ArticleThe researchers observed that the combined protective effect of hydrogen and oxygen was superior to their respective protective effects, and the specific molecular mechanisms of the two therapies…
Read ArticleIn participants, interestingly, the hydrogen-rich water group had a higher volume of water intake as compared to the control group, with regular water consumption (81.8 ± 5.1 mL/day…
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