Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In rats, treatment with HRS had no significant effect on blood pressure, but it significantly improved baroreflex function in SHR. Although treatment with HRS had no significant effect on nitric oxide amount in circulating or aorta, it suppressed endothelial nitric oxide synthase…
Read ArticleIn Sprague-Dawley rats, inhalation of 1.2% H₂ gas protected the endothelial glycocalyx and prolonged survival time during hemorrhagic shock. These preclinical findings add evidence supporting molecular hydrogen's therapeutic…
Read ArticleIn mice, intraperitoneal injection of H₂ prevented cardiac hypertrophy and improved cardiac function in ISO-infused mice. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the…
Read ArticleThe results showed that, compared with the AFB1 group, the AFB1+H₂ group exhibited increased body weights, alleviated acute liver injury, decreased activities of serum glutamic-pyruvic transaminase and glutamic…
Read ArticleIn The authors' research suggests that the galvanic cells for hydrogen therapy based on implantable metals may be a safe and effective cancer treatment, the authors' research suggests…
Read ArticleIn vitro studies confirmed that H₂ released from CB@Anaerobic-Gel disrupts redox homeostasis and suppresses mitochondrial respiration in colon cancer cells. These findings from a laboratory model add evidence…
Read ArticleThis in vitro or cellular study examined Hydrogen peroxide inhibits the growth of lung cancer cells via the induction of cell death and G1‑phase arrest. The abstract describes…
Read ArticleIn 42 patients with lung cancer treated with nivolumab, the 42 patients treated with hydrogen gas and nivolumab (HGN) indicated a significantly longer overall survival (OS) compared with…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Growing evidence has shown that hydrogen gas can either alleviate the side effects caused by conventional chemotherapeutics, or suppress the…
Read ArticleIn a laboratory model, due to puncture positioning, the acidic tumor microenvironment and gas diffusion effect, the developed H₂ generation electrochemotherapy (H₂-ECT) strategy enables precise and large-scale tumor…
Read ArticleIn vivo, it achieves efficient tumor homing, suppresses tumor growth in both immunodeficient and immunocompetent models, and reprograms the TME by lowering Tregs and M2 macrophages while enhancing…
Read ArticleIn These data show that, after standard treatments had failed, hydrogen-gas monotherapy elicited significant effective control of tumors (especially those in the brain), and survival time was lengthened,…
Read ArticleIn However, by providing tolerance to various stressors, autophagy promotes the survival and proliferation of cancer cells and confers resistance to chemotherapy, the combination of EHW with anticancer…
Read ArticleIn a laboratory model, here, targeting gastric cancer, a 2D magnesium boride nanosheet (MBN) is synthesized as a new type of acid-responsive hydrogen-releasing prodrug by an ultrasound-assisted chemical…
Read ArticleIn The effect of H₂ on the proliferation and apoptosis of RKO, SW480, and HCT116 CRC cell lines was assayed by CCK-8, colony formation, and flow cytometry assays,…
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