Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In Sprague-Dawley rats, the JAK-STAT (Janus Kinase-Signal transducers and activators of transcription) signaling molecule expressions were decreased with hydrogen-rich saline treatment. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in this model.
Read ArticleIn an animal model, h(2) treatment decreased serum ox-LDL level and apoptosis in plaques with concomitant inhibition of endoplasmic reticulum stress (ERS) and reduction of reactive oxygen species…
Read ArticleIn mice, atherosclerotic lesions were significantly reduced by ad libitum drinking of H(2)-water (p=0.0069) as judged by Oil-Red-O staining series of sections of aorta. These preclinical findings add…
Read ArticleIn 8 participants, fMD increased in the high-H₂ group (eight males; eight females) from 6.80%±1.96% to 7.64%±1.68% (mean ± standard deviation) and decreased from 8.07%±2.41% to 6.87%±2.94% in…
Read ArticleIn mice, the numbers of endothelial cells in the atheroma expressing the senescence factors p16INK4a and p21 decreased in HFD-fed mice given HW compared with HFD-fed mice given…
Read ArticleIn Sprague-Dawley rats, mitochondrial ATP content, mitochondrial complex I, and mitochondrial complex III activity were significantly decreased in the MI group, which was improved after hydrogen administration. These…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. This article highlights the dual role of diet in generating molecular hydrogen ( H₂ ) in the gut, and H₂…
Read ArticleIn mice, H₂ prevents the decreased density and reverses the morphologic and functional changes in retinal astrocytes caused by oxygen-induced injury. The authors linked these findings to activation…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. In this review, evidence of the potential benefits of hydrogen molecules obtained from in vitro, in vivo, and clinical investigations…
Read ArticleIn rats, the study shows that HRSS is protective in IR injury, with the application of HRSS 5 min before reperfusion, interstitial edema severity, subendocardial haemorrhage are reduced,…
Read ArticleDrinking HRW increased the maximum power and average power of the 30 s rowing test and decreased the maximum heart rate during the period. This source-grounded publication contributes…
Read ArticleIn this report, the researchers showed a KD patient with an aneurysm over the right coronary artery with a size of 6.08 mm in diameter and 35 mm…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Irradiation of the rats caused a significant increase in lipid peroxidation, which was mitigated by pre-treatment of the animals with…
Read ArticleIn rats, H₂ present in KHB during HPostC further decreased IS/AR compared with the effect of HPostC, attenuated severe arrhythmias, and significantly restored heart function (vs. controls). These…
Read ArticleIn this pilot study, hydrogen inhalation during percutaneous coronary intervention was feasible and safe and may have promoted favorable left-ventricular remodeling six months after STEMI. This small, open-label,…
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