Exploratory Evaluation of Hydrogen-Rich Water Therapy for Keloid Management: A Double-Blinded Randomized Pilot Trial.
In 21 patients, anti-inflammatory cytokine IL-10 levels significantly increased after hydrogen-rich water therapy, while inflammation-related cytokines VEGF and TGF-β levels significantly decreased. These findings add human evidence supporting molecular hydrogen's therapeutic potential to influence inflammatory regulation.
Read MoreAssociation Between Hydrogen-Rich Water Consumption and Lower Extremity Function in Older Adults Participating in Community Salons: A Prospective Observational Study
In community-dwelling older adults participating in community salons, routine hydrogen-rich water consumption was associated with improved lower extremity function as measured by CS-30 and gait speed. This source-grounded publication contributes evidence relevant to molecular hydrogen and is retained in a transparent general research category when a more specific study design is not supported by the indexed record.
Read MoreHydrogen-Rich Water as a Novel Therapeutic Strategy for the Affective Disorders Linked with Chronic Neuropathic Pain in Mice.
Hydrogen-rich water reduced pain hypersensitivity and anxiety- and depression-like behaviors in mice with chronic neuropathic pain. These results are preclinical and suggest molecular hydrogen's therapeutic potential in the condition studied. Further human research is needed to establish clinical effectiveness.
Read MoreTherapeutic Potential of Hydrogen-Rich Water on Muscle Atrophy Caused by Immobilization in a Mouse Model.
In male Balb/C mice, treatment by HRW increased CSA and muscle fiber size and reduced muscle fibrosis, serum troponin I, IL-6, TNF-α and MDA which was more prominent in the atrophy phase. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in this model.
Read MoreHydrogen-rich water protects against acetaminophen-induced hepatotoxicity in mice.
In mice, the malonyldialdehyde (MDA) contents were significantly reduced in the HRW pretreatment group, but they were increased in the APAP-treated group (10.44 ± 1.339 nmol/mg protein vs 16.70 ± 1.646 nmol/mg protein, P < 0.05). These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in this model.
Read MoreAlleviation of cadmium toxicity in Medicago sativa by hydrogen-rich water.
The addition of HRW at 10% saturation significantly decreased contents of thiobarbituric acid reactive substances (TBARS) caused by Cd, and inhibited the appearance of Cd toxicity symptoms, including the improvement of root elongation and seedling growth. This source-grounded publication contributes evidence relevant to molecular hydrogen and is retained in a transparent general research category when a more specific study design is not supported by the indexed record.
Read MorePotential ghrelin-mediated benefits and risks of hydrogen water.
In mice, a recent study in mice has discovered that orally administered HW provokes increased gastric production of the orexic hormone ghrelin, and that this ghrelin mediates the favorable impact of HW on a mouse model of Parkinson's disease. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in this model.
Read MoreInhibition of streptococcal biofilm by hydrogen water.
In In vitro streptococcal biofilm was quantified using crystal violet staining after culture on a polystyrene plate, the data showed that H-water caused a significant decrease in in vitro streptococcal biofilm formation. The authors concluded that the data suggest that oral rinse with H-water would be helpful in treating dental biofilm-dependent diseases with ease and efficiency. These findings from a laboratory model add evidence supporting molecular hydrogen's biological and therapeutic potential in the model studied.
Read MoreEffect of supplementation with hydrogen-rich water in patients with interstitial cystitis/painful bladder syndrome.
In 30 participants, however, the effect of hydrogen-rich water on symptoms was not significantly different from that of placebo, although supplementation with hydrogen-rich water was extremely effective in improving the bladder pain score in 11% of the patients.
Read MoreEffects of Hydrogen-rich Water on Cariogenic Bacteria.
In a laboratory model, bacterial growth and biofilm formation were inhibited, and the number of CFUs was significantly reduced in the EHW group compared to the control group. The authors concluded that exposing cariogenic bacteria to EHW at neutral pH for one minute can effectively inhibit bacterial growth and biofilm formation in vitro, suggesting that EHW is a promising mouthwash. These findings from a laboratory model add evidence supporting molecular hydrogen's biological and therapeutic potential in the model studied.
Read MoreThe effect of hydrogen-rich water consumption on premenstrual symptoms and quality of life: a randomized controlled trial.
This human study examined the effect of drinking HRW on the severity of premenstrual symptoms and the quality of life of women who suffer from PMS. These findings add human evidence supporting molecular hydrogen's therapeutic potential across the specific human outcomes evaluated in this study.
Read MoreHydrogen-rich water alleviates the toxicities of different stresses to mycelial growth in Hypsizygus marmoreus.
HRW treatment, of which the H₂ concentration was 0.8 mM, significantly reduced the toxicities of CdCl2, NaCl and H₂O₂, leading to significantly improved mycelial growth and biomass. This source-grounded publication contributes evidence relevant to molecular hydrogen and is retained in a transparent general research category when a more specific study design is not supported by the indexed record.
Read MoreHeat-retention effects of hydrogen-rich water bath assessed by thermography for humans.
In 24 healthy participants, the thermograms indicated that, under the same conditions (41 °C, 10-min bathing), hydrogen-rich water bath (hydrogen concentrations: 185-548 μg/L; oxidation-reduction potentials: -167 to -91 mV, versus 0.8 μg/L and +479 mV for normal bath, respectively) brought about the heat-retention being more marked than those of normal water bath for several body-parts in the order as follows. Abdomen > upper legs > arms > hands > feet, for 30- and 60-min post-bathing, being in contrast to scarce heat-retention for head, armpits and lower legs. These findings add human evidence supporting molecular hydrogen's therapeutic potential across the specific human outcomes evaluated in this study.
Read MoreHydrogen-rich water attenuates the radiotoxicity induced by tritium exposure in vitro and in vivo.
In an animal model, showed that intragastric administration of HRW effectively promoted the elimination of urinary tritium, decreased the level of serum tritium and tissue-bound tritium (OBT), and attenuated the genetic damage of blood cells in mice exposed to HTO (18.5 MBq/kg). These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in this model.
Read MoreHydrogen-rich water as a modulator of gut microbiota?
This publication examined hydrogen-rich water using the study design reported by the authoritative source. This source-grounded publication contributes evidence relevant to molecular hydrogen and is retained in a transparent general research category when a more specific study design is not supported by the indexed record.
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