Protective effect of hydrogen-rich water on spermatogenesis in high-fat diet obese rats.
This publication is an erratum or correction associated with a molecular-hydrogen article. It does not report a new standalone experiment.
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The effect of hydrogen gas on the oxidative stress response in adipose tissue.
In 12 patients, hYDROGEN SOLUTION PREPARATION AND CONCENTRATION MEASUREMENT: The day before the experiment, 500 mL of Dulbecco’s modified Eagle’s medium (low glucose) supplemented with L-glutamine and phenol…
Read ArticleThe Effects of 8-Week Hydrogen-Rich Water Consumption on Appetite, Body Composition, Sleep Quality, and Circulating Glucagon-like Peptide-1 in Obese Men and Women (HYDRAPPET): A Randomized Controlled Trial.
The results demonstrated that hydrogen-rich water significantly mitigated cravings (p = 0.05), improved subjective sleep quality (p = 0.05), reduced total cholesterol (p = 0.02) and LDL cholesterol…
Read ArticleTreatment with hydrogen-rich water protects against thioacetamide-induced hepatic encephalopathy in rats through stabilizing liver-brain disturbance.
In rats, compared with N group, the percentage of time spent in the target quadrant and the frequency of crossing the platform of rats in T group were…
Read ArticleRole of molecular hydrogen in obesity treatment: modulation of GLP-1, irisin, and PGC-1α for improved metabolism.
This narrative review examined the available molecular-hydrogen literature. 2 For example, a 6-month randomized clinical trial involving 1088 patients with type 2 diabetes mellitus (T2DM) receiving standard anti-diabetic…
Read ArticleHydrogen-rich water protects against ischemic brain injury in rats by regulating calcium buffering proteins.
In an animal model, HRW prevented the ischemia-induced reduction of parvalbumin and hippocalcin levels in vivo and also reduced the glutamate toxicity-induced death of neurons, including the dose-dependent…
Read ArticleHydrogen alleviates hypoxic-ischaemic brain damage in neonatal rats by inhibiting injury of brain pericytes.
In rats, HRW treatment decreased DAPI/PI/β‐PDGFR and β‐PDGFR/ROS‐positive cells while increasing the β‐PDGFR/SOD‐positive cells, indicating that HRW attenuated HI‐induced oxidative stress injury in pericytes (Figure 1B–D ). These…
Read ArticleMolecular hydrogen modulates brain glutamate/GABA-glutamine cycle in overweight humans.
The researchers showed a possible hydrogen-driven upregulation of neurotransmitters involved in appetite stimulation leading to hunger suppression and weight loss. This source-grounded publication contributes evidence relevant to molecular…
Read ArticleHydrogen-rich water and caffeine for alertness and brain metabolism in sleep-deprived habitual coffee drinkers.
In 16 apparently healthy, young participants, both HRW and caffeine significantly increased the choline-to-creatine ratio in several brain regions (frontal white and gray matter), while HRW and the…
Read ArticleHydrogen inhalation protects hypoxic-ischemic brain damage by attenuating inflammation and apoptosis in neonatal rats.
In rats, hypoxia–ischemia induced neuronal damage and increased the expression of the apoptotic factors, P-JNK, and p53, which were attenuated by hydrogen inhalation (P < 0.05). These preclinical…
Read ArticleHydrogen-rich water improves sleep consolidation and enhances forebrain neuronal activation in mice.
In mice, HRW increased sleep consolidation in undisturbed mice and increased non-rapid-eye movement and rapid-eye-movement sleep amount in sleep-deprived mice. These preclinical findings add evidence supporting molecular hydrogen's…
Read ArticleTranscriptomic and metabolomic studies on the protective effect of molecular hydrogen against nuclear electromagnetic pulse-induced brain damage.
In rats, the data from the elevated plus maze and the open field test showed that NEMP exposure elicited anxiety-like behavior in rats, which could be alleviated by…
Read ArticleMolecular Hydrogen Reverses Nociplastic Pain and Depressive-like Behaviors via Region- and Sex-Dependent Central Mechanisms.
In female C57BL/6 mice, at the molecular level, HRW reduced spinal oxidative stress and ERK-dependent plasticity without altering spinal NLRP3 expression, whereas it fully reversed NLRP3 upregulation and…
Read ArticleStructural and lipid peroxidation effects of lead on rat hippocampus and its attenuation by hydrogen rich water.
In rats, concluded that HRW protects the neurons against lead-induced oxidative stress and has anti-apoptotic effects without a noticeable change in NO level which already was diminished by…
Read ArticleHydrogen in Transplantation: Potential Applications and Therapeutic Implications.
This narrative review examined the available molecular-hydrogen literature. The authors highlighted early evidence of cytoprotective, antioxidant, and anti-inflammatory effects. The reviewed evidence adds support for molecular hydrogen's therapeutic…
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