Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In Sprague-Dawley rats, prenatal H₂ administration improved respiratory function by attenuating lung morphology and pulmonary artery thickening in CDH rat models. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in this model.
Read ArticleThis narrative review examined the available molecular-hydrogen literature. The threshold shifts in animals given GeO 2 and hydrogen water showed approximately 20–30 threshold shifts at all frequencies, which…
Read ArticleIn 9 patients with hypercholesterolemia and their underlying mechanisms in a double-blinded, H₂ treatment increased the effective rate in down-regulating plasma levels of total cholesterol (47.06% vs 17.65%)…
Read ArticleIn 52 physically active, healthy participants, intake of HRW significantly increased fasting arterial blood pH by 0.04 (95% confidence interval; 0.01 - 0.08; p < 0.001), and postexercise…
Read ArticleIn 26 participants, these results suggest that HRW may reinforce QOL through effects that increase central nervous system functions involving mood, anxiety, and autonomic nerve function. These findings…
Read ArticleIn mice, cUMS induced elevation in IL-1β protein levels in the hippocampus, and the cortex was significantly attenuated after 4 weeks of feeding the mice hydrogen-rich water. These…
Read ArticleIn mice, post hoc analysis showed that HRW administration in PVS and PVL groups significantly attenuated the increased serum levels of TNF-α of male ( P < 0.05,…
Read ArticleIn mice, treatment with HRW intraperitoneally administered at 2T per day over two consecutive days normalized the increased immobility time observed in CFA-injected animals treated with VEH in…
Read ArticleIn male Wistar rats, HRW treatment consistently reduced MDA levels and substantially restored catalase activity in the liver and testis (p < 0.05, p < 0.01). The combined…
Read ArticleIn mice, the H₂ concentration immediately increased in the liver but not in the kidney after drinking HW. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential…
Read ArticleIn participants, dual-echo MRI revealed that HRW significantly reduced liver fat accumulation in individual liver regions-of-interest at 28-day follow-up, as compared to placebo administration (P < 0.05). These…
Read ArticleIn 30 patients with NAFLD and 15 healthy volunteers were included in this clinical trial, after 8 weeks of adjuvant therapy with HRW, the concentration of CoQ10 in…
Read ArticleIn rats, no significant differences in dissolved H₂ or ORP values were observed in the HRW samples either at 4 °C or at 25 °C within 24 h.…
Read ArticleIn an animal model, mechanistically, the researchers discovered that sustained and ultrahigh H₂ supply by hydrogen nanocapsule increased, among other species, the abundance of Akkermansia muciniphila, highlighting reshaped…
Read ArticleIn mice, compared to RW and L-HRW, H-HRW resulted in a lower increase in fat mass (46% vs 61%), an increase in lean body mass (42% vs 28%),…
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