Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In mice, H₂ decreases H₂O₂ -induced pro-inflammatory cytokine release in human bronchial epithelial cells Under the exposure of 42% H₂, concentration of H₂ in cell culture medium gradually increased with the exposure time, and H₂ concentration in cell culture medium was saturated…
Read ArticleThe results indicated that 2% H₂ gas treatment increased the survival rates, decreased the W/D weight ratio and the lung injury score, alleviated the injuries caused by oxidative…
Read ArticleIn rabbits, hydrogen gas inhalation markedly improved lung endothelial permeability and decreased both MDA content and MPO activity in lung tissue; these changes were associated with decreases in…
Read ArticleIn rats, low expression of AhR in lung tissues determined by Western Blot was found after CAPs exposure, whereas hydrogen inhibited AhR decline induced by CAPs. These preclinical…
Read ArticleIn rats, as shown in this study, a reduction of TNF-α and IL-1β by 2% hydrogen gas inhalation may ultimately reduce the incidence of lung injury from the…
Read ArticleIn mice, hydrogen decreased malondialdehyde and increased superoxide dismutase activity in lung tissues. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological…
Read ArticleIn mice, hCH Inhalation significantly alleviated LPS-induced pathological alterations of lung, and reduced the protein concentration, the wet/dry weight ratio, and the MPO activity of lung tissue. These…
Read ArticleIn C57BL/6 mice, levels of inflammatory cytokines (interleukin-1β, interleukin-6, and tumor necrosis factor α) and oxidative stress markers (ie, malondialdehyde) were significantly lower, whereas antioxidant enzyme (total superoxide…
Read ArticleIn rats, hRS at a dose of 20 mg/kg, administered intraperitoneally 30 min before ischemia in rats, reduced lipid peroxidation and oxidative stress, while also reducing IR damage…
Read ArticleIn an animal model, aquaporin 1(AQP1) and AQP5 have an important role in eliminating extravascular lung water, an increase of which contributes to lung injury in patients with…
Read ArticleIn rats, combined early fluid resuscitation and hydrogen inhalation may protect the lung and intestine of the septic shock rats from the damage induced by oxidative stress and…
Read ArticleIn rats, hydrogen water ameliorated these alterations, demonstrating that hydrogen water alleviated paraquat-induced acute lung injury possibly by inhibition of oxidative damage. These preclinical findings add evidence supporting…
Read ArticleIn mice, as a result, Apoa2 protein or mRNA was identified as a target biomarker for H₂ with a protective, causal relationship with sepsis. These preclinical findings add…
Read ArticleIn mice, compared with the Sham group, mitochondrial dysfunction was alleviated in hydrogen groups. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and…
Read ArticleIn male C57BL/6 mice, hydrogen inhalation also significantly reduced inflammatory cytokine and chemokine mRNA levels and improved oxygenation. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential…
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