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In rats, at 24 hours, 48 hours, 1 week and 2 weeks after injury showed that hydrogen-rich saline markedly reduced cell death, inflammatory cell infiltration, serum malondialdehyde content, and caspase-3 immunoreactivity, elevated serum superoxide dismutase activity and calcitonin gene-related peptide immunoreactivity, and…
Read ArticleHydrogen Inhalation during Ex Vivo Lung Perfusion Ameliorates the Quality of Lung Grafts in Rats is classified as Animal study using Preclinical animal evidence. The primary model is…
Read ArticleIn contrast, treatment with HW improved allograft function, slowed the progression of CAN, reduced oxidant injury and inflammatory mediator production, and improved overall survival. These results are preclinical…
Read ArticleIn rats, reduced cytokine expression by FOS feeding might be dependent on increased colonic H₂. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes…
Read ArticleIn rats, they demonstrate that the addition of hydrogen to the drinking water In a decrease in the severity of CAN and increased graft survival, and they provide…
Read ArticleThese preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in this model.
Read ArticleIn male Sprague-Dawley rats, both HBO and HRS treatments increase the rate of flap survival, while the synergistic application of HBO and HRS showed a higher survival rate…
Read ArticleIn rats, compared with rats with I/R only, hydrogen-rich saline treatment significantly improved the amount of surviving cells. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential…
Read ArticleThe researchers showed that irrigation of the cornea with hydrogen (H₂) solution significantly reduced angiogenesis after alkali-burn injury (P<0.01). These preclinical findings add evidence supporting molecular hydrogen's therapeutic…
Read ArticleIn mice, infarct zone and area with loss of tissue structure and marked cellular infiltration were significantly decreased in groups treated by hydrogen gas inhalation during ischemia-reperfusion; however,…
Read ArticleIn Sprague-Dawley rats, the cell viability was significantly decreased after irradiation (P= 0.001), but pre-treatment with hydrogen before irradiation increased the cell viability (P= 0.025). These preclinical findings…
Read ArticleCg-Leprcp/NDmcr rats treated with HRW showed a 34% decrease in ROS production. These results are preclinical and suggest molecular hydrogen's therapeutic potential in the condition studied. Further human…
Read ArticleSerum cardiac troponin T and S100B measured during earlier post-resuscitation period were markedly reduced in both H₂ inhalation and hypothermic groups. These results are preclinical and suggest molecular…
Read ArticleIn female Sprague Dawley rats, hydrogen-rich saline attenuated the FSH release, elevated the level of E2, improved the development of follicles, and reduced the damage to the ovarian…
Read ArticleIn rats, rats in the H₂ group displayed a reduced degree of myocardial neutrophilic infiltrate, necrosis, hemorrhage, and spindle‐shaped interstitial cells as compared with rats in the Control…
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