Hydrogen inhalation ameliorates ventilator-induced lung injury.
This uncontrolled human study examined Hydrogen inhalation ameliorates ventilator-induced lung injury. The abstract describes Human participants; sample size 8; hydrogen delivered as hydrogen inhalation; reported duration 2 hours. The abstract reports: Inhaled hydrogen gas effectively reduced VILI-associated inflammatory responses, at both a local and systemic level, via its antioxidant, anti-inflammatory and antiapoptotic effects. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas inhalation protects against cigarette smoke-induced COPD development in mice.
This animal study examined Hydrogen gas inhalation protects against cigarette smoke-induced COPD development in mice. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: These findings demonstrated that H inhalation could inhibit CS-induced COPD development in mice, which is associated with reduced ERK1/2 and NF-κB-dependent inflammatory responses. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas reduces HMGB1 release in lung tissues of septic mice in an Nrf2/HO-1-dependent pathway.
This uncontrolled human study examined Hydrogen gas reduces HMGB1 release in lung tissues of septic mice in an Nrf2/HO-1-dependent pathway. The abstract describes Human participants. The abstract reports: The results indicated that 2% H gas treatment increased the survival rates, decreased the W/D weight ratio and the lung injury score, alleviated the…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Gas Inhalation Attenuates Seawater Instillation-Induced Acute Lung Injury via the Nrf2 Pathway in Rabbits.
This animal study examined Hydrogen Gas Inhalation Attenuates Seawater Instillation-Induced Acute Lung Injury via the Nrf2 Pathway in Rabbits. The abstract describes Rabbit model; hydrogen delivered as hydrogen inhalation. The abstract reports: These results demonstrate that hydrogen gas inhalation attenuates seawater instillation-induced acute lung injury in rabbits and that the protective effects observed may be related…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen ameliorates lung injury in a rat model of subacute exposure to concentrated ambient PM2.5 via Aryl hydrocarbon receptor.
This animal study examined Hydrogen ameliorates lung injury in a rat model of subacute exposure to concentrated ambient PM2.5 via Aryl hydrocarbon receptor. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: High concentrations of hydrogen could ameliorate pulmonary dysfunction, airway mucus hypersecretion, oxidation damage, and inflammation response in rats exposed to concentrated ambient PM2.5. Additionally,…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas inhalation ameliorates lung injury after hemorrhagic shock and resuscitation.
This animal study examined Hydrogen gas inhalation ameliorates lung injury after hemorrhagic shock and resuscitation. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: Inhalation of 2% hydrogen gas after HSR minimized the extent of lung injury by decreasing MPO activity and reducing infiltration of inflammatory cells into…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen alleviates acute lung injury induced by limb ischaemia/reperfusion in mice.
This animal study examined Hydrogen alleviates acute lung injury induced by limb ischaemia/reperfusion in mice. The abstract describes Mouse model; hydrogen delivered as injected or infused hydrogen. The abstract reports: Molecular hydrogen exhibited a protective effect on the LIR-induced ALI model. Hydrogen decreased malondialdehyde and increased superoxide dismutase activity in lung tissues. Additionally, hydrogen…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHigh concentration of hydrogen gas alleviates Lipopolysaccharide-induced lung injury via activating Nrf2 signaling pathway in mice.
This animal study examined High concentration of hydrogen gas alleviates Lipopolysaccharide-induced lung injury via activating Nrf2 signaling pathway in mice. The abstract describes Mouse model. The abstract reports: HCH can effectively alleviate LPS-induced ALI, which may be related to activation of Nrf2 signaling pathway and inhibition of inflammatory response and cell apoptosis…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEvaluation of the therapeutic effects of nebulized inhalation of hydrogen-rich water on primary blast lung injury in C57BL/6 mice.
This animal study examined Evaluation of the therapeutic effects of nebulized inhalation of hydrogen-rich water on primary blast lung injury in C57BL/6 mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water and injected or infused hydrogen. The abstract reports: The overpressure generated by blasts leads to alveolar and capillary damage, resulting in ventilation-perfusion mismatch and increased intrapulmonary shunting. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEvaluation of the effect of enriched hydrogen saline solution on distant organ (lung) damage in skeletal muscle ischemia reperfusion in rats.
This animal study examined Evaluation of the effect of enriched hydrogen saline solution on distant organ (lung) damage in skeletal muscle ischemia reperfusion in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: HRS at a dose of 20 mg/kg, administered intraperitoneally 30 min before ischemia in rats, reduced lipid peroxidation and oxidative stress, while also reducing IR damage…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of hydrogen-rich saline on aquaporin 1, 5 in septic rat lungs.
This uncontrolled human study examined Effects of hydrogen-rich saline on aquaporin 1, 5 in septic rat lungs. The abstract describes Human participants; hydrogen delivered as hydrogen-rich saline. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreCombined early fluid resuscitation and hydrogen inhalation attenuates lung and intestine injury.
This animal study examined Combined early fluid resuscitation and hydrogen inhalation attenuates lung and intestine injury. The abstract describes Rat model; sample size 15; hydrogen delivered as hydrogen inhalation. The abstract reports: Combined early fluid resuscitation and hydrogen inhalation may protect the lung and intestine of the septic shock rats from the damage induced by oxidative…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreConsumption of hydrogen water reduces paraquat-induced acute lung injury in rats.
This animal study examined Consumption of hydrogen water reduces paraquat-induced acute lung injury in rats. The abstract describes Rat model; hydrogen delivered as hydrogen water and hydrogen-rich saline and injected or infused hydrogen. The abstract reports: The results showed that hydrogen water ameliorated these alterations, demonstrating that hydrogen water alleviated paraquat-induced acute lung injury possibly by inhibition of oxidative damage. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreAPOA2: New Target for Molecular Hydrogen Therapy in Sepsis-Related Lung Injury Based on Proteomic and Genomic Analysis.
This animal study examined APOA2: New Target for Molecular Hydrogen Therapy in Sepsis-Related Lung Injury Based on Proteomic and Genomic Analysis. The abstract describes Mouse model. The abstract reports: Animal experiments helped validate these results. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHigh Concentration Hydrogen Mitigates Sepsis-Induced Acute Lung Injury in Mice by Alleviating Mitochondrial Fission and Dysfunction.
This animal study examined High Concentration Hydrogen Mitigates Sepsis-Induced Acute Lung Injury in Mice by Alleviating Mitochondrial Fission and Dysfunction. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: Lungs are among the organs that are affected in MOF, resulting in acute lung injury. This is an automated editorial draft based on the abstract and requires source review before publication.
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