Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In dogs, among all groups, NAD content and the number of apoptotic and 8-OHdG positive cells was not significantly different, indicating that the cardioprotection afforded by H(2) was not due to anti-oxidative actions or effects on the NADH dehydrogenase pathway. These preclinical…
Read ArticleThe results demonstrated that H₂-treated mice showed significantly shorter escape latency, longer target quadrant duration, and higher NOR index compared to controls. These preclinical findings add evidence supporting…
Read ArticleIn male C57BL/6 mice, hydrogen preconditioning significantly reduced MDA levels and enhanced MnSOD activity, which peaked 24 h postinjury. These preclinical findings add evidence supporting molecular hydrogen's therapeutic…
Read ArticleIn male Wistar rats, fluid resuscitation with 2% hydrogen inhalation decreased serum creatinine, blood urea nitrogen, and neutrophil gelatinase-associated lipocalin. These preclinical findings add evidence supporting molecular hydrogen's…
Read ArticleIn mice, this study proved that prophylactic treatment with DULO combined with HRW prevented the mechanical allodynia and muscle strength deficits caused by CIS in mice of both…
Read ArticleIn rats, bOLD MRI may be useful for demonstrating the change in R2 in CP-induced nephrotoxicity in rats. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential…
Read ArticleIn rats, there were no significant differences in the normalised K value between the treatment and control groups on days 2 and 7. These preclinical findings add evidence…
Read ArticleIn Sprague-Dawley rats, compared with the Lop group, the abundance of Firmicutes (86.70% vs 91.77%) increased whereas that of Bacteroidetes (7.50% vs 5.26%) and Actinobacteria (3.03% vs 0.81%)…
Read ArticleIn rats, histopathologically, a decrease in degenerative cells was observed in the treatment group (i.e., HI+H₂). These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the…
Read ArticleThe researchers found that the beneficial effects of HS treatment on SAH-induced CV were associated with decreased levels of lipid peroxidation, increased activity of antioxidant enzymes, and reduced…
Read ArticleIn conclusion, HS may inhibit inflammation in EBI and improve neurobehavioral outcome after SAH, partially via inactivation of NF-κB pathway and NLRP3 inflammasome. These preclinical findings add evidence…
Read ArticleThe results suggest activation of Nrf2/Keap1 pathway as well as increased SOD1 protein expression in the group treated with H₂. These preclinical findings add evidence supporting molecular hydrogen's…
Read ArticleIn rats, hydrogen-rich saline improved acidosis and renal function and reduced the release of inflammatory factors (TNF, IL-1β, and IL-6). These preclinical findings add evidence supporting molecular hydrogen's…
Read ArticleIn rats, compared with controls, the H₂ and Mg groups had significantly reduced total depolarization and hypoperfusion times. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential…
Read ArticleIn mice, hypoxia exposure led to changes in the diversity of gut microbiota, along with a decrease in the abundance of aerobic bacteria and beneficial bacteria (e.g., Lactobacillus),…
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