Molecular hydrogen protects mice against polymicrobial sepsis by ameliorating endothelial dysfunction via an Nrf2/HO-1 signaling pathway.
The researchers found that both 0.3 mmol/L and 0.6 mmol/L (i.e., saturated) H₂-rich media improved cell viability and cellular apoptosis in LPS-activated HUVECs and that 0.6mmol/L (i.e., saturated) H₂-rich medium exerted an optimal effect. These preclinical findings add evidence supporting molecular hydrogen's…
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