Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In a laboratory model, this combination therapy may be more effective than separate drug treatment; it decreased the malondialdehyde level and increased the superoxide dismutase activity. The authors concluded that the results further suggested that the combination therapy may reduce cell proliferation…
Read ArticleH2HUBB TAKEAWAY This human study examined the present study was conducted to investigate the protective effect of hydrogen-rich water on the liver function of colorectal cancer (CRC) patients…
Read ArticleIn a laboratory model, electrolyzed reduced water (ERW) produced near the cathode during the electrolysis of water scavenged intracellular H(2)O(2) and decreased the release of H(2)O(2) from a…
Read ArticleIn This study aimed to investigate the role of H₂ incombination with 5-fluorouracil (5-FU) in cancer treatment both in vitro and in vivo using the colon 26 cell…
Read ArticleIn mice, marked aggression of the tumors was found, leading to the possibility that hyperbaric hydrogen therapy might also prove to be of significance in the treatment of…
Read ArticleIn These findings should provide insights into the mechanism of inhibition of H₂-silica on human cancer cells in vitro, apoptosis-inducing effect on KYSE-70 cells was observed in 10,…
Read ArticleIn mice, the expression of Ki-67, VEGF and SMC3 were decreased when mice were treated with H₂ or cis-platinum, especially for cis-platinum. These preclinical findings add evidence supporting…
Read ArticleIn male HR-1 hairless mice, H₂ preserved the GSH/GSSG ratio following acute UVB exposure and reduced nuclear Nrf2 accumulation during chronic exposure. These preclinical findings add evidence supporting…
Read ArticleIn participants with radiotherapy or concurrent chemo-radiotherapy, qoL improved in the HW group (p = 0.03), while OFC scores showed no significant difference between groups (p = 0.74).…
Read ArticleThis preclinical study evaluated hydrogen gas in an animal model. These results are preclinical and suggest molecular hydrogen's therapeutic potential in the condition studied. Further human research is…
Read ArticleIn Balb/c mice, administration of HRW + 5-FU significantly improved tumor weight, tumor size, collagen content and fibrosis as compared to the CRC control group. These preclinical findings…
Read ArticleCombined treatment with H₂ and Pt-nc resulted in an approximately 200-fold increase in intracellular ROS levels compared with the control, whereas the suppressive effect of tumor cell growth…
Read ArticleIn a laboratory model, find that the localized release of hydrogen increases the expression level of P53 tumor suppressor proteins, as demonstrated by the in vitro RNA sequencing…
Read ArticleIn 20 patients, after 2 weeks of hydrogen therapy, the number of exhausted and senescent cytotoxic T cells decreased to within the normal range, and there was an…
Read ArticleIn the authors' previous study, the authors' project group found that H₂ could decrease the expression of CD47 in lung cancer A549 cells via the next-generation sequencing, indicating…
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