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In guinea pigs, strong immunoreactivities against 8-OHdG were observed of the non-treated group, the H₂-treated group showed decreased immunoreactivity for 8-OHdG. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in this model.
Read ArticleThese findings add human evidence supporting molecular hydrogen's therapeutic potential to influence oxidative-stress regulation.
Read ArticleThe results of the H&E, and Nissl staining indicated that the CLP mice had a significant brain injury, which was characterized by aggravated pathological damage and was alleviated…
Read ArticleIn rats, hydrogen (2.9%) administered concurrently with surgery significantly decreased the formation of cerebral edema (p = 0.028) and improved neurobehavioral score (p = 0.022). These preclinical findings…
Read ArticleIn Both groups received standard treatment plus 4 daily 1-h interventions for 14 consecutive days, although it is generally safe and feasible, its potential effects on myocardial, liver…
Read ArticleThis narrative review examined metabolomic and phosphoproteomic analyses were utilized to explore the therapeutic mechanism of H₂. The WB and IF results revealed that DGKζ expression increased in…
Read ArticleThe researchers administered hydrogen capsules as a novel adjunct therapy, beginning daily treatment immediately upon admission. These findings add human evidence supporting molecular hydrogen's therapeutic potential to influence…
Read ArticleThis publication is an erratum or correction associated with a molecular-hydrogen article. It does not report a new standalone experiment.
Read ArticleIn conclusion, combined H₂ gas ventilation and TH increased CBV and decreased ScO2, which may reflect elevated cerebral blood flow to meet greater oxygen demand for the surviving…
Read ArticleIn an animal model, this study used a swine model of mildly hypothermic prolonged circulatory arrest and found that the addition of 2.4% inhaled hydrogen gas to inspiratory…
Read ArticleIn rats, pretreatment with H₂ inhalation significantly attenuated seizure intensity; prevented neuronal loss; decreased microglial and astrocytic activation; decreased ROS, TNF-α, IL-1β, IL-6, CCL2 and CCL3 levels; and…
Read ArticleThis publication is an erratum or correction associated with a molecular-hydrogen article. It does not report a new standalone experiment.
Read ArticleIn mice, 5 In the present study, the researchers quantitatively assessed the changes in protein phosphorylation in the H₂ ‐treated CLP model mice and identified functions and signalling…
Read ArticleIn mice, the authors' recent studies provided evidence that hydrogen inhalation can selectively reduce cytotoxic oxygen radicals and exert antioxidant effects. These preclinical findings add evidence supporting molecular…
Read ArticleIn guinea pigs, aBR thresholds were significantly lower in H₂-treated animals at 2 weeks after exposure, with significant preservation of outer hair cells in the entire cochlea. These…
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