Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In guinea pigs, a HILIC-UHPLC-Q-TOF-MS-based protocol for untargeted metabolomics of perilymph is presented and shown to be fit-for-purpose. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in this model.
Read ArticleIn Twenty, physically active female participants aged 22, compared with placebo (ambient air), molecular hydrogen inhalation significantly decreased respiratory exchange ratio and ventilation across all intervals. These findings…
Read ArticleIn mice, cEO administration and H₂ inhalation alone or in combination positively improved inflammation-induced anxiety, depression, and cognitive memory deficits in the mice. These preclinical findings add evidence…
Read ArticleHydrogen intervention, including drinking and inhaling, significantly alleviated mental disorders induced by METH abuse, and the inhalation of hydrogen also altered gut microbiota profiles in the METH abusers.…
Read ArticleIn an animal model, there was no significant difference in changes of portal vein pressure between two groups at pre-operation, PH 30 min, but in hydrogen gas treated-group…
Read ArticleIn Sprague-Dawley rats, H₂ improved the hepatic histological changes and glucose tolerance, decreased the liver function parameters of plasma alanine aminotransferase and aspartate aminotransferase, and relieved liver inflammation.…
Read ArticleIn mice, inhalation of hydrogen gas (1-4%) during the last 190min suppressed hepatic cell death, and reduced levels of serum alanine aminotransferase and hepatic malondialdehyde. These preclinical findings…
Read ArticleIn rats, inhalation of hydrogen gas at 2% concentration for 1 h significantly reduced the serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) activities, the expression of cytokines,…
Read ArticleThe results demonstrated that 2% H₂ gas inhalation resulted in an increase in the 7-day survival rate, ALT and AST levels, RCR, and P62 and LC3B-II expression but…
Read ArticleIn mice, among these, Acaca, Fasn, and CD36 were decreased ( Figures 2G-I ), while Mttp and Apob were increased by high dose H₂ therapy ( Figures 2N,O…
Read ArticleThis publication examined hydrogen gas using the study design reported by the authoritative source. No study results are reported because this publication is a protocol.
Read ArticleIn rats, rats exposed 2 h daily to H₂ either by drinking HRW (H₂ dissolved in H₂O) or by breathing 4% H₂ gas showed reduced lipogenesis and enhanced…
Read ArticleIn rats, when the hydrogen gas was inhaled, hepatocyte steatosis was reduced, and the UCP2 expression level in liver tissue was increased. These preclinical findings add evidence supporting…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. H₂ gas inhalation has been associated with improved recovery from ischemia-reperfusion injury, which is commonly encountered with kidney transplants and…
Read ArticleIn blood gases, pH, PaO 2, and BE decreased and lactate increased, but recovered to baseline after 3 h, with no difference between the HI and HI-H₂ groups…
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