Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
This narrative review examined the available molecular-hydrogen literature. H₂ has been found to have selective antioxidant properties against the most dangerous oxidants (hydroxyl radicals and peroxynitrite). The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes…
Read ArticleIn participants, the pooled effect sizes of H₂ on RPE (SMDpooled = -0.38, 95%CI -0.65 to -0.11, p = 0.006, I 2 = 33.6%, p = 0.149) and…
Read ArticleIn mice, it was found that the collagen content of the treatment group was comparable to that of the control group and the hydrogen water group at 3…
Read ArticleThe authors concluded that administration of hydrogen-rich water improves lung function and alleviates morphological impairments of lung through alleviating inflammation, reducing oxidative stress and lessening mucus hypersecretion in…
Read ArticleIn male Sprague-Dawley rats, hydrogen-rich saline treatment decreased the neutrophil infiltration, the lipid membrane peroxidation, NF-kappaB activation and the pro-inflammatory cytokine interleukin IL-1beta and TNF-alpha in the lung…
Read ArticleIn mice, inhaled hydrogen gas effectively reduced VILI-associated inflammatory responses, at both a local and systemic level, via its antioxidant, anti-inflammatory and antiapoptotic effects. These preclinical findings add…
Read ArticleIn mice, H₂ decreases H₂O₂ -induced pro-inflammatory cytokine release in human bronchial epithelial cells Under the exposure of 42% H₂, concentration of H₂ in cell culture medium gradually…
Read ArticleThe results indicated that 2% H₂ gas treatment increased the survival rates, decreased the W/D weight ratio and the lung injury score, alleviated the injuries caused by oxidative…
Read ArticleIn rats, low expression of AhR in lung tissues determined by Western Blot was found after CAPs exposure, whereas hydrogen inhibited AhR decline induced by CAPs. These preclinical…
Read ArticleIn rats, as shown in this study, a reduction of TNF-α and IL-1β by 2% hydrogen gas inhalation may ultimately reduce the incidence of lung injury from the…
Read ArticleIn mice, hCH Inhalation significantly alleviated LPS-induced pathological alterations of lung, and reduced the protein concentration, the wet/dry weight ratio, and the MPO activity of lung tissue. These…
Read ArticleIn C57BL/6 mice, levels of inflammatory cytokines (interleukin-1β, interleukin-6, and tumor necrosis factor α) and oxidative stress markers (ie, malondialdehyde) were significantly lower, whereas antioxidant enzyme (total superoxide…
Read ArticleIn the smoking subgroup, IL-6 level and neutrophil count also decreased significantly after hydrogen-oxygen inhalation (both P<0.01), while CRP remained relatively stable. These findings add human evidence supporting…
Read ArticleIn rats, hRS at a dose of 20 mg/kg, administered intraperitoneally 30 min before ischemia in rats, reduced lipid peroxidation and oxidative stress, while also reducing IR damage…
Read ArticleIn rats, combined early fluid resuscitation and hydrogen inhalation may protect the lung and intestine of the septic shock rats from the damage induced by oxidative stress and…
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