Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
This narrative review examined the available molecular-hydrogen literature. The authors highlighted early evidence of cytoprotective, antioxidant, and anti-inflammatory effects. The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.
Read ArticleH(2) is a therapeutic antioxidant that can reduce oxidative stress. These findings come from a laboratory model and suggest molecular hydrogen's biological potential. Further research is needed to…
Read ArticleIn male Wistar rats, hW intake may prevent lipid deposition in the rat aorta induced by periodontitis by decreasing serum ox-LDL levels and aortic oxidative stress. These preclinical…
Read ArticleIn male Sprague-Dawley rats, sTZ-diabetic rats were marked by clearly reduced b-wave amplitudes and oscillatory potentials, DM-related BRB breakdown and histological changes in the inner retina, all of…
Read ArticleIn an animal model, inhalation of hydrogen gas protects against myocardial stunning and infarction in swine. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the…
Read ArticleIn rats, using this system, the concentration of H₂ in unit volume can be greatly improved under normal temperature and pressure conditions. These preclinical findings add evidence supporting…
Read ArticleIn male Wistar rats, the apoptosis rate was significantly decreased in the hydrogen-rich water group, as well. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within…
Read ArticleIn rats, nFkB-p65 and c-Fos in the nucleus were unexpectedly unchanged by IRI regardless of H₂ treatment, indicating the absence of inflammation in this model. These preclinical findings…
Read ArticleIn an animal model, the NT, H₂, and H₂ -TH groups showed a significant reduction in HR at 0 h (end of insult), whereas the TH group showed…
Read ArticleIn Pulmonary microvascular endothelial cells were divided into 4 groups: blank, control, oxygen (O₂), and H₂, the pH values in the O₂ (7.17 ± 0.05) and H₂ groups…
Read ArticleIn rats, hydrogen-containing saline (HCS) treatment was observed to improve interstitial fibrosis and cardiac function and to decrease the level of ROS, the oxidative‑stress marker MDA and expression…
Read ArticleIn mice, although treatment of diabetic mice with hydrogen water did not significantly affect blood glucose level, it significantly attenuated cardiac hypertrophy and reduced expression of atrial natriuretic…
Read ArticleIn an animal model, although the W/D ratio in the CPB group significantly increased as compared with that in the SHAM group, such an increase was also suppressed…
Read ArticleIn rats, it also decreased neutrophil infiltration, 3-nitrotyrosine level, expression of intercellular adhesion molecule 1(ICAM-1) and myeloperoxidase (MPO) activity in the area at risk zones (AAR) of rat…
Read ArticleIn a laboratory model, xIE et al: Nrf2/HO-1 PATHWAY MEDIATES H₂ GAS MYOCARDIAL PROTECTION114 8 agent CoCl2, at 400 -1,000 µM for 24 h, reduced cell viability in…
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