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Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In rats, increased expression of TJ proteins occludin and ZO-1 by reducing various parameters of ERS and ERS-induced apoptosis evidenced by down-regulation of the protein levels of GRP78, XBP1, CHOP and caspase-3 were shown in the HRS and 4-PBA groups. These preclinical…
Read ArticleIn an animal model, HRW treatment increased the hydrogen levels of the stomach and duodenum. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes…
Read ArticleIn rats, hRSS is effective in reducing the intestinal damage caused by an IRI: HRSS has the potential to reduce the detrimental effects of intestinal anastomosis performed after…
Read ArticleIn rats, however, hydrogen-rich saline treatment significantly increased the 24-h survival of rats to 53.33% (8 of 15 rats) in the HRS1 group and 86.67% (13 of 15…
Read ArticleIn Tissue oxidative stress was analyzed with immunostaining for 8-hydroxy-2'-deoxyguanosine (8-OHdG), hydrogen mitigated such apoptosis at the crypt base, and the LGR5 expression of the tissues was higher…
Read ArticleIn This study utilized next-generation sequencing (NGS) to assess mRNA and miRNA expression in EHW-treated Caco-2 cells, eHW treatment significantly decreased the levels of miR-429 and miR-200c-3p and…
Read ArticleIn rats, this study provides biochemical and histomorphological evidence that HRSS prevents intestinal damage in I/R injury caused by volvulus. These preclinical findings add evidence supporting molecular hydrogen's…
Read ArticleIn male C57BL/6 mice, HRW treatment partially ameliorated colitis symptoms, improved histopathological changes, significantly increased glutathione (GSH) concentration and decreased TNF-α level. These preclinical findings add evidence supporting…
Read ArticleIn rats, meanwhile, the increased MPO level in the EHW-administered group significantly reduced 2 ( p = 0.0011) and 4 ( p = 0.0009) days post TNBS treatment…
Read ArticleIn Finally, cells from the macrophage cell line RAW264 were co-cultured with the supernatants of cecal contents, microscopic evaluation revealed that luminal ROS was significantly reduced and that…
Read ArticleIn rats, the authors' present study showed that hydrogen treatment lessened the stress-induced lipid peroxidation, protein carbonyl and DNA oxidant and improved tissue antioxidant potential. These preclinical findings…
Read ArticleIn In conclusion, H₂ could protect IPEC-J2 cells from DON-induced oxidative damage and apoptosis in vitro, however, H₂ efficiently reduced the LDH release ( p < 0.05) and…
Read ArticleIn rats, plasma cytokines concentrations were reduced in H₂ saline-treated TP rats. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways…
Read ArticleIn mice, bowel dysmotility, induced by surgical manipulation and inflammatory events, was significantly attenuated by intra-abdominal administration of hydrogen-rich saline. These preclinical findings add evidence supporting molecular hydrogen's…
Read ArticleIn rats, although enhanced MDA levels were observed in all of the injured animals, the elevation appeared to be significantly inhibited by hydrogen-rich saline treatment ( P <…
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