Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In an animal model, HRW treatment increased the hydrogen levels of the stomach and duodenum. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in this model.
Read ArticleIn male C57BL/6 mice, HRW treatment partially ameliorated colitis symptoms, improved histopathological changes, significantly increased glutathione (GSH) concentration and decreased TNF-α level. These preclinical findings add evidence supporting…
Read ArticleIn Finally, cells from the macrophage cell line RAW264 were co-cultured with the supernatants of cecal contents, microscopic evaluation revealed that luminal ROS was significantly reduced and that…
Read ArticleIn Sprague-Dawley rats, the serum tumor necrosis factor-α content increased significantly in I/R + saline group, but HRW treatment reduced serum tumor necrosis factor-α content as compared to…
Read ArticleThe researchers showed that 8-OHdG, but not MDA, significantly increased by 149% and 145% in HU-NW and HU-AEW, respectively, when compared with CONT. These preclinical findings add evidence…
Read ArticleIn mice, the pivotal proteins involved in endoplasmic reticulum (ER) stress, including p-eIF2α, ATF4, XBP1s and CHOP, were dramatically reduced after HRW treatment in contrast to the control…
Read ArticleIn rats, the oxidative stress levels of MDA and MPO in the gastric tissues increased significantly in the aspirin-treated group compared with the HRW group (2.43 ± 0.145…
Read ArticleIn the intestinal tissue, compared with the LPS group, the HRW + LPS group had decreased the levels of IL-1β and TNF-α ( Figure 2 B, p <…
Read ArticleIn mice, although sulfasalazine significantly reduced MDA levels compared to the colitis model (P < 0.001), H₂ with and without sulfasalazine was significantly more effective compared to sulfasalazine…
Read ArticleIn rats, HRW treatment effectively alleviated the degenerative changes in the retinal outer nuclear layer, improved retinal function, and reduced retinal inflammation in treated rats. These preclinical findings…
Read ArticleIn male Sprague-Dawley rats, these results indicated that peritoneal injection of HRS provides protection and treatment against light-induced retinal degeneration in rats. These preclinical findings add evidence supporting…
Read ArticleHowever, no significant difference in mean IOP was observed before and after HRW consumption (t = 1.115, P = 0.276) ( Table 2 ). These findings add human…
Read ArticleIn participants, these findings suggest that acute intermittent hydration with HRW enhances muscle function, mitigates the lactate response, and alleviates delayed-onset muscle soreness [ 23 ]. These findings…
Read ArticleIn a laboratory model, either administered as an inhalational gas, enteral hydrogen-rich water, or intravenous hydrogen-rich water, H₂ seems to favorably affect various exercise performance outcomes and biomarkers…
Read ArticleIn 128 participants, self-selected hydrogen-rich water consumption was associated with better chair-stand performance and gait speed in this pragmatic community setting, but residual confounding remains possible. These findings…
Read Article