Hydrogen-rich saline protects rat from oxygen glucose deprivation and reperusion-induced apoptosis through VDAC1 via Bcl-2.
This animal study examined Hydrogen-rich saline protects rat from oxygen glucose deprivation and reperusion-induced apoptosis through VDAC1 via Bcl-2. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: HRS ameliorated OGD/RP-induced PC-12 cell apoptosis and provided a novel treatment option for ischemia. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen improves obesity and diabetes by inducing hepatic FGF21 and stimulating energy metabolism in db/db mice.
This in vitro or cellular study examined Molecular hydrogen improves obesity and diabetes by inducing hepatic FGF21 and stimulating energy metabolism in db/db mice. The abstract describes Fibroblast model. The abstract reports: To examine how drinking H(2)-water improves obesity and metabolic parameters at the molecular level, we examined gene-expression profiles, and found enhanced expression of a…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffect of hydrogen-rich water on the lactic acid level in metformin-treated diabetic rats under hypoxia.
This uncontrolled human study examined Effect of hydrogen-rich water on the lactic acid level in metformin-treated diabetic rats under hypoxia. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: We found that the levels of lactic acid, pyruvate and lactate dehydrogenase were significantly lower in the blood of DMMHR group than DMMH group. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreSuppressive effects of electrolyzed reduced water on alloxan-induced apoptosis and type 1 diabetes mellitus.
This animal study examined Suppressive effects of electrolyzed reduced water on alloxan-induced apoptosis and type 1 diabetes mellitus. The abstract describes Mouse model. The abstract reports: Here, we showed that electrolyzed reduced water prevented alloxan-induced DNA fragmentation and the production of cells in sub-G1 phase in HIT-T15 pancreatic β-cells. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline improves non‑alcoholic fatty liver disease by alleviating oxidative stress and activating hepatic PPARα and PPARγ.
This animal study examined Hydrogen-rich saline improves non‑alcoholic fatty liver disease by alleviating oxidative stress and activating hepatic PPARα and PPARγ. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The present study evaluated the effects of H2 on NAFLD in rats and concluded that H2‑rich saline had significant therapeutic effects on NAFLD induced…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePreservative effect of electrolyzed reduced water on pancreatic beta-cell mass in diabetic db/db mice.
This animal study examined Preservative effect of electrolyzed reduced water on pancreatic beta-cell mass in diabetic db/db mice. The abstract describes Mouse model. The abstract reports: The present data suggest that ERW may protects beta-cell damage and would be useful for antidiabetic agent. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effects of hydrogen-rich saline against erectile dysfunction in a streptozotocin induced diabetic rat model.
This animal study examined Protective effects of hydrogen-rich saline against erectile dysfunction in a streptozotocin induced diabetic rat model. The abstract describes Rat model; sample size 8; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen; reported duration 8 weeks. The abstract reports: Hydrogen-rich saline effectively improved erectile function in a streptozotocin induced diabetic rat model of erectile dysfunction. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreAnti-diabetic effects of electrolyzed reduced water in streptozotocin-induced and genetic diabetic mice.
This animal study examined Anti-diabetic effects of electrolyzed reduced water in streptozotocin-induced and genetic diabetic mice. The abstract describes Mouse model. The abstract reports: Oxidative stress is produced under diabetic conditions and is likely involved in progression of pancreatic beta-cell dysfunction found in diabetes. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreTherapeutic effects of hydrogen saturated saline on rat diabetic model and insulin resistant model via reduction of oxidative stress.
This animal study examined Therapeutic effects of hydrogen saturated saline on rat diabetic model and insulin resistant model via reduction of oxidative stress. The abstract describes Rat model; hydrogen delivered as injected or infused hydrogen. The abstract reports: Hydrogen saturated saline may improve the insulin resistance and alleviate the symptoms of diabetes mellitus by reducing the oxidative stress and enhancing the anti-oxidant…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreOral Intake of Hydrogen Water Improves Retinal Blood Flow Dysregulation in Response to Flicker Stimulation and Systemic Hyperoxia in Diabetic Mice.
This animal study examined Oral Intake of Hydrogen Water Improves Retinal Blood Flow Dysregulation in Response to Flicker Stimulation and Systemic Hyperoxia in Diabetic Mice. The abstract describes Mouse model; sample size 6; hydrogen delivered as hydrogen water. The abstract reports: Hydrogen-rich water intake significantly improved RBF dysregulation in diabetic mice. Hydrogen may improve impaired neurovascular coupling function in diabetic mice by suppressing gliosis and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline prevents bone loss in diabetic rats induced by streptozotocin.
This animal study examined Hydrogen-rich saline prevents bone loss in diabetic rats induced by streptozotocin. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The results indicate that the systemic delivery of hydrogen saline water, which is safe and well tolerated, preserves bone volume and decreases fracture risks…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen improves type 2 diabetes through inhibiting oxidative stress.
This animal study examined Molecular hydrogen improves type 2 diabetes through inhibiting oxidative stress. The abstract describes Rat model; hydrogen delivered as injected or infused hydrogen; reported duration 4 weeks. The abstract reports: The results showed that in rats with T2DM, molecular hydrogen treatment decreased fasting blood glucose levels, increased hepatic glycogen synthesis and improved insulin sensitivity. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreSilicon nanoparticles for oral administration of molecular hydrogen.
This animal study examined Silicon nanoparticles for oral administration of molecular hydrogen. The abstract describes Animal model. The abstract reports: Silicon particles are suggested for oral administration with the ability to undergo a redox reaction with water to produce Hin vivo. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreSimultaneous oral and inhalational intake of molecular hydrogen additively suppresses signaling pathways in rodents.
This animal study examined Simultaneous oral and inhalational intake of molecular hydrogen additively suppresses signaling pathways in rodents. The abstract describes Mouse model. The abstract reports: We first examined the H2 concentrations in blood and organs after its administration and found that oral intake of HRW rapidly but transiently increased…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreOral intake of hydrogen-rich water inhibits intimal hyperplasia in arterialized vein grafts in rats.
This animal study examined Oral intake of hydrogen-rich water inhibits intimal hyperplasia in arterialized vein grafts in rats. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: Drinking HW significantly reduced neointima formation after vein grafting in rats. Drinking HW may have therapeutic value as a novel therapy for intimal hyperplasia…. This is an automated editorial draft based on the abstract and requires source review before publication.
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