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In mice, the study verified a catalytic strategy of combining PdH nanoparticles and hydrogen inhalation, which exhibited enhanced anti-inflammatory effect for CLD treatment. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in this…
Read ArticleIn rats, when the hydrogen gas was inhaled, hepatocyte steatosis was reduced, and the UCP2 expression level in liver tissue was increased. These preclinical findings add evidence supporting…
Read ArticleIn an animal model, HRW improved hepatic steatosis in the CSAA + HRW group. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and…
Read ArticleIn rats, r(2)* values in the cortex were significantly decreased on Days 2, 4, and 7 compared with those on Day 0 in the GM group but not…
Read ArticleIn male Sprague-Dawley rats, 6d ), although there were statistically significant differences in M30 CytoDeath-positive cells (0.7 ± 0.1 and 0.9 ± 0.2 positive cells/field in the Fe-HD…
Read ArticleIn blood gases, pH, PaO 2, and BE decreased and lactate increased, but recovered to baseline after 3 h, with no difference between the HI and HI-H₂ groups…
Read ArticleIn rats, hRS reversed these changes, with the exception of HO-1 expression, which was increased further, and improved renal morphology. These preclinical findings add evidence supporting molecular hydrogen's…
Read ArticleIn an animal model, marginal kidney processed by hydrogen gas-containing preservation solution has been engrafted for long-term (longer than 100 days). These preclinical findings add evidence supporting molecular…
Read ArticleIn an animal model, after storage of the kidney in hydrogen-free preservation solution for 1 hour before transplantation, no urine production was observed and blood flow was not…
Read ArticleIn an animal model, nineteen serum metabolites and 7 urine metabolites showed significant restoration to normal levels after hydrogen gas (H₂) treatment. These preclinical findings add evidence supporting…
Read ArticleIn mice, however, the proportion of M1-type macrophages was significantly lower and the proportion of M2-type macrophages was significantly higher in the hydrogen-rich-medium-treated LPS/IFN-γ group than in the…
Read ArticleIn male Sprague-Dawley rats, kEY FINDINGS: the researchers demonstrated that rats who inhale hydrogen gas showed improved renal function, alleviated pathological damage, oxidative stress and apoptosis in CIH…
Read ArticleIn rats, after I/R injury, BUN, Cr, Bcl-2, caspase-3, caspase-9, caspase-8, IL-6, and TNF-α were all significantly increased, while Bax expression was decreased. These preclinical findings add evidence…
Read ArticleIn contrast, treatment with HW improved allograft function, slowed the progression of CAN, reduced oxidant injury and inflammatory mediator production, and improved overall survival. These results are preclinical…
Read ArticleIn rats, as shown in Figures 7(d) and 8(c), the expression of I κ B and IL-10 in renal tissues at 12 hours was significantly decreased after SAP…
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