Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In mice, all parameters of inflammation (foot volume, infiltration of neutrophils, amount of TNF-α and the level of TNF-α's mRNA) were attenuated by the hydrogen saline treatment. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological…
Read ArticleIn mice, repeated inhalation of hydrogen-oxygen mixed gas [67%:33% (V/V)] significantly decreased both the acute and chronic stress-induced depressive- and anxiety-like behaviors of mice, assessed by tail suspension…
Read ArticleIn mice, the inhalation of H₂ (2%) or hyperoxia (98%) alone improved the 14-day survival rate of ZY-challenged mice from 20 to 70 or 60%, respectively. These preclinical…
Read ArticleIn an animal model, have found an increased survival rate of bacteria-challenged zebrafish subjected to the HRW immersion treatment. These preclinical findings add evidence supporting molecular hydrogen's therapeutic…
Read ArticleIn mice, at day-7, DSS-induced pathogenic outcomes including, loss of body weight, increase of colitis score, pathogenic shortening of colon length, elevated level of IL-12, TNF-alpha and IL-1beta…
Read ArticleThe researchers found that resuscitation by hydrogen-rich saline alleviated inflammation significantly. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured…
Read ArticleIn guinea pigs, both the number and biological activity of CD4+CD25+Foxp3+Treg cells increased with up-regulation of Th1/Th2 after hydrogen-rich saline administration. These preclinical findings add evidence supporting molecular…
Read ArticleIn mice, treatment of ovalbumin-sensitized and challenged mice with hydrogen reversed the energy metabolic pathway switch, and mitigated airway inflammation. These preclinical findings add evidence supporting molecular hydrogen's…
Read ArticleIn mice, 3.3 Immunoblot analysis of the tibialis cranialis muscle showed that Nrf2 protein expression was significantly lower in the HRW group than in the PW group, both…
Read ArticleIn rats, oxidant status in biochemical analyses decreased in the stress + HRW group compared to the stress group. These preclinical findings add evidence supporting molecular hydrogen's therapeutic…
Read ArticleIn an animal model, the cumulative mortality rate of SVCV-infected zebrafish was reduced by 40% after treatment with nano-bubble hydrogen water, and qRT-PCR results showed that SVCV replication…
Read ArticleIn male Sprague Dawley rats, three models showed the same result that hydrogen-rich water had an efficient protective effect on acute peritonitis. These preclinical findings add evidence supporting…
Read ArticleIn mice, enzyme-linked immunosorbent assay performed on day 7 revealed that hydrogen water reduced the level of the pro-inflammatory cytokine interleukin-6 and increased that of forkhead box P3…
Read ArticleIn mice, this study demonstrates new protective actions of H₂ and suggests that treatment with HRW might be an interesting therapeutic strategy for chronic neuropathic pain and its…
Read ArticleIn male Balb/C mice, showed that after 7 days of immobilization, serum troponin I levels in the atrophy group were significantly increased compared to the control and that…
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