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Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In mice, the renal expressions of osteopontin (OPN), CD44, monocyte chemoattractant protein-1 (MCP-1) and interleukin-10 (IL-10) were markedly increased in glyoxylate-treated mice, and H₂ significantly attenuated the increase of OPN, CD44 and MCP-1 but upregulated the expression of IL-10. These results are…
Read ArticleIn Balb/c mice, renal function was also impaired in the experimental group with UUO, with an increase of Scr and BUN in serum. These preclinical findings add evidence…
Read ArticleIn the early phases, HRUW solution decreased oxidative stress, tubular apoptosis, and interstitial macrophage infiltration in the kidney grafts. These preclinical findings add evidence supporting molecular hydrogen's therapeutic…
Read ArticleIn mice, however, the levels of a-SMA and Col I expression were sharply decreased in the IR+HRS group (P < 0.05). These preclinical findings add evidence supporting molecular…
Read ArticleIn rats, one day after the injection, serum levels of urea nitrogen were significantly lower in H₂ gas-inhaling CIAKI rats (17.6 ± 2.3 mg/dl) than those in control…
Read ArticleIn rats, of scores for kidney appearance showed that for 4% H₂ inhalation, morphological lesions were alleviated in about 70% rats of this group, while for 67% H₂…
Read ArticleIn conclusion, HRW restored the balance of redox status, suppressed oxidative stress damage, and improved kidney function induced by CsA via activation of the Keap1/Nrf2 signaling pathway. The…
Read ArticleIn mice, crystal deposition, tubular injury, fibrosis and increased ROS production in kidneys of mice induced by oxalate diet were improved with HRW administration. These preclinical findings add…
Read ArticleIn rats, this experiment showed that the effect of drinking large volumes of hydrogen-rich water was not significantly different from that of normal water, in terms of preventing…
Read ArticleIn mice, here, the researchers demonstrate that hydrogen nanobubble water (HNW), an improved and stabilized oral formulation of molecular hydrogen, reduces cochlear injury induced by noise exposure. These…
Read ArticleIn guinea pigs, hRS reduced the ROS and MDA levels and increased SOD level in guinea pigs of AR-HRS group accompanied with decreased frequency of sneezing and scratches.…
Read ArticleThe researchers found that the beneficial effects of H₂ treatment on ZY-induced organ damage were associated with the decreased levels of oxidative product, increased activities of antioxidant enzyme,…
Read ArticleIn mice, H₂ administration also resulted in significantly higher progesterone levels compared with LPS treatment alone (P=0.002). These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within…
Read ArticleIn rats, H₂ improved HO-1 mRNA and protein expression and activities in the process of pain. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the…
Read ArticleIn the case of infected groups, the group fed ERW (ERW+E. hortense group) showed the result that IL-4, IL-5, IL-10 and Ig A expression increased, but IL-1beta and…
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