Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In Sprague-Dawley rats, hRS treatment maintained the body weight, reduced the incidence of NEC from 85% (17/20) to 54.5% (12/22), increased the survival rate from 25% (5/20) to 68.2% (15/22), and attenuated the severity of NEC. These preclinical findings add evidence about…
Read ArticleIn rats, treatment with hydrogen-rich saline reduced the weight loss and diarrhea and alleviated the colonic mucosal damage in the UC rats. These preclinical findings add evidence supporting…
Read ArticleIn participants, the effect of reducing oxidative stress, thus allowing for improved sleep, was exhibited by drinking AEW containing hydrogen, which is considered to be an antioxidant substance.…
Read ArticleThe researchers showed that 8-OHdG, but not MDA, significantly increased by 149% and 145% in HU-NW and HU-AEW, respectively, when compared with CONT. These preclinical findings add evidence…
Read ArticleIn in vitro experiment, HRS treatment reduced miR-199a-3p level, increase IGF-1, PI3K and mTOR mRNA expression, restore IEC-6 cells viability, and this protective effects were reversed under miR-199a-3p…
Read ArticleIn mice, table 1 Effects of molecular hydrogen-dissolved alkaline electrolyzed water on physical parameters at 4 weeks of treatment Biochemical parameters of the serum obtained from mice administered…
Read ArticleIn a laboratory model, molecular hydrogen treatment promoted PKM2 lactylation without affecting total PKM2 expression. The authors concluded that molecular hydrogen can promote PKM2 lactylation to restrain NLRP3…
Read ArticleIn mice, the pivotal proteins involved in endoplasmic reticulum (ER) stress, including p-eIF2α, ATF4, XBP1s and CHOP, were dramatically reduced after HRW treatment in contrast to the control…
Read ArticleIn rats, the oxidative stress levels of MDA and MPO in the gastric tissues increased significantly in the aspirin-treated group compared with the HRW group (2.43 ± 0.145…
Read ArticleIn vitro analysis of cytokine levels after LPS treatment of cultured macrophages showed an increase of interleukin-10 by hydrogen regardless of the presence of nitric oxide. The authors…
Read ArticleIn an animal model, body mass was 36.4 (35.1–37.9) and 36.9 (34.4–38.4) kg in the control and hydrogen groups, respectively ( p = 0.89). These preclinical findings add…
Read ArticleThe findings suggest that treatment with molecular hydrogen may affect microbiota profiling and suppress intestinal injury in HFD-loaded SAMP8. These preclinical findings add evidence supporting molecular hydrogen's therapeutic…
Read ArticleThese findings add human evidence that helps define the outcomes that did and did not change with molecular hydrogen in this study.
Read ArticleIn the intestinal tissue, compared with the LPS group, the HRW + LPS group had decreased the levels of IL-1β and TNF-α ( Figure 2 B, p <…
Read ArticleIn mice, although sulfasalazine significantly reduced MDA levels compared to the colitis model (P < 0.001), H₂ with and without sulfasalazine was significantly more effective compared to sulfasalazine…
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